Editor: Satish Ramalingam

Cancer Genes

Volume 2

eBook: US $89 Special Offer (PDF + Printed Copy): US $153
Printed Copy: US $108
Library License: US $356
ISBN: 978-981-5136-51-7 (Print)
ISBN: 978-981-5136-50-0 (Online)
Year of Publication: 2023
DOI: 10.2174/97898151365001230201

Introduction

Cancer Genes is a comprehensive list of the most critical genes known to contribute to cancer imitation and progression. The book delves into their location on each chromosome, providing valuable insights into the mechanisms of cancer gene dysregulation and genetic mutations which provide cancer cells with an advantage during each stage of tumorigenesis. The reference will familiarize readers with the location of cancer genes and equip them with the necessary information to identify relevant gene expression targets for research aimed at preventing the disease.

The book is divided into two volumes focusing on cancer-causing genes found in chromosome pairs 1-12 (volume 1), and chromosomes 13-23 (volume 2). A key features of the book is a detailed reference list for advanced readers. The compilation is therefore a quick and handy reference on cancer causing genes for researchers, medical professionals, and anyone interested in understanding the genetic basis of cancer.

Audience:

Researchers (genetics, molecular biology and life sciences), medical professionals (oncologists), and anyone interested in understanding the genetic basis of cancer.

Foreword

The collection of diseases known as cancer has been recognized as a deadly disease for more than 4000 years. Amazing improvements in the treatment of cancer have occurred in the past century. Still, however, understanding of the molecular basis of cancers’ origins remains incomplete. Neoplasms are complex diseases that involve mutations or aberrant expression of dozens of genes. The pace of cancer genetics research has expanded exponentially following the sequencing of the human genome. While a tremendous boon for cancer researchers, there have been numerous missed opportunities because the overwhelming numbers of papers published make it nearly impossible for any cancer researcher to keep up.

Dr. Satish Ramalingam and colleagues provide this extensive compendium of cancer genes. The catalog summarizes key data which implicates each gene in one or more cancers and summarizes key studies that explore each mechanism of action. The organization, by the chromosomes on which the genes are encoded, allows both experts and neophytes to cross-reference and facilitate their research objective(s).

The monograph is a compendious primer that will be a valuable resource for cancer biologists, clinical oncologists and students engaging in basic discovery, translational research, or clinical treatment of cancer.

Danny R. Welch, PhD
University of Kansas Cancer Center