Editors: Tilak Saha, Manab Deb Adhikari, Bipransh Kumar Tiwary

Recent Trends and The Future of Antimicrobial Agents - Part 2

eBook: US $69 Special Offer (PDF + Printed Copy): US $110
Printed Copy: US $76
Library License: US $276
ISBN: 978-981-5123-98-2 (Print)
ISBN: 978-981-5123-97-5 (Online)
Year of Publication: 2023
DOI: 10.2174/97898151239751230101


Recent Trends and the Future of Antimicrobial Agents provides a significantly expanded overview of the topic with updated research in a broader context on the development of alternative approaches against microbial infections.

This part primarily describes the use of probiotics, chemically synthesized compounds and nanomaterials as antimicrobial agents. The first chapter describes the potential of probiotics for the restoration of gut microbiomes. Amongst various antimicrobial agents, the use of antibodies has recently been investigated as a potential remedy. A chapter on antibody-based therapy as an alternative to antibiotics has been included. Chemical synthesis has eased the development of target-based prospective drug molecules against microorganisms. Chemically synthesized cationic amphiphiles and amphiphilic nanocarriers as antimicrobial agents have been discussed with sufficient detail in two different chapters. Research and progress in Schiff Base-Metal Complexes and Metal-Organic Frameworks for their antimicrobial applications have also been described in two separate chapters. Independent chapters discussing the design, synthesis and antimicrobial applications of biogenic metal or metalloid nanoparticles, bactericidal QDs and MoS2-based antibacterial nanocomposites have fulfilled the aim of incorporating cutting-edge research in the areas of alternative antimicrobials. Also, a new-age approach to combat microbes, antimicrobial photodynamic therapy (aPDT), is discussed in the final chapter of the edited volume. This part intends to provide the readers with an updated and broad view of research and development in alternative remedial approaches against microbial infections.

The contents cater to the information needs of professionals and learners in academia, industry and health services who aim to learn the most significant experimental and practical approaches towards finding alternatives to existing antimicrobial therapies.


Researchers at the graduate and postgraduate levels, healthcare professionals


The book “Recent Trends and The Future of Antimicrobial Agents” tries to explore various alternatives of multi drug resistant bacteria which are the major causes of therapeutic failure. The book provides various approaches to the solution and each section describes and analyses the approach towards the problem. Research is going on globally on various alternatives to treatment like Plant based antimicrobials, Photodynamic therapies, enzyme based and antibody based antimicrobial approaches, chemical compounds that act as antimicrobial agents, nano-materials which act as antimicrobial agents, probiotic, prebiotic and peptides compounds or agents. The writers have taken up each scenario to make the readers understand about the macro and micro factors associated with the approach.

The book attempts to throw light on the various aspects of the pathogenic multi drug resistant bacteria and takes a wide horizon on the impact of antibiotics on them. The discovery of penicillin paved the way for the antibiotics to become popular but as the bacteria can accumulate on multiple genes making them resistant to a particular drug, similarly the resistance can also be caused by an increased expression of genes responsible for multi-drug efflux pumps forcing out a lot many drugs. Hence the need to develop an alternative strategy is very critical for therapeutic success. The book describes all these scenarios in two subsequent volumes of the title. Volume-1 includes the naturally derived antimicrobial remedies/strategies. The Volume-2 of the same title incorporates the chemical and advanced nanomaterial based strategies along with sustainable antimicrobial strategies viz. use of probiotics and photodynamic therapy. I would like to thank the authors for their dedicated effort and the publishers in converting that effort into a reality. I am sure that the information will be very useful for Clinicians as well as Microbiologists.

Dhrubajyoti Chattopadhyay
PhD, F.A.Sc , F.Na.Sc , F.A.Sc.T
Vice Chancellor
Sister Nivedita University