Editors: Ipek Suntar, Davide Barreca, Luigi Milella

Methods for Preclinical Evaluation of Bioactive Natural Products

eBook: US $69 Special Offer (PDF + Printed Copy): US $110
Printed Copy: US $76
Library License: US $276
ISBN: 978-981-5123-05-0 (Print)
ISBN: 978-981-5123-04-3 (Online)
Year of Publication: 2023
DOI: 10.2174/97898151230431230101

Introduction

Natural products have dominated our lives since ancient times. Today, they are an inexhaustible source of new medications for disease treatment. The practice of evaluating bioactive compounds extracted from natural sources has also advanced significantly, prompting a need to understand current methods to identify and evaluate them.

This book covers basic scientific aspects of preclinical research on natural products for specific conditions and diseases. These include aging, gynecological disorders, inflammatory disorders, renal disorders and cardiovascular disorders. Each of the 10 book chapters give a structured overview on preclinical methods on the etiology of diseases, natural products as the materials for the bioassays, extract types, concentration of the extracts/compounds for in vitro and in vivo assays, preparation of the test materials, application of the test materials, step-by-step methods and related calculations.

The book is intended as a quick reference for natural product researchers, pharmacists and postgraduate students in pharmacognosy. Medical doctors working in preclinical research on natural products will also benefit from the information provided.

Audience

Natural product researchers, pharmacists and postgraduate students in pharmacognosy. Medical doctors working in preclinical research on natural products.

Preface

- Pp. i
Ipek Suntar, Davide Barreca, Luigi Milella
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List of Contributors

- Pp. ii-iii (2)

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Antioxidant Activity Methods

- Pp. 1-69 (69)
Immacolata Faraone, Daniela Russo, Fabiana Labanca, Ludovica Lela, Maria Ponticelli, Chiara Sinisgalli, Luigi Milella*

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Antidiabetic Activity Methods

- Pp. 70-100 (31)
Cigdem Kahraman, Iffet Irem Tatli Cankaya*

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Anti-inflammatory Activity Methods

- Pp. 101-126 (26)
Giovanni Enrico Lombardo, Alessandro Maugeri, Caterina Russo, Laura Musumeci, Santa Cirmi*, Michele Navarra*

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Antimicrobial Activity Methods

- Pp. 127-148 (22)
Teresa Gervasi, Giuseppina Mandalari*

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Cytotoxic Activity Methods

- Pp. 149-176 (28)
Esra Emerce*, Kevser Taban Akça

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Activity Methods for Endometriosis

- Pp. 177-199 (23)
Murside Ayse Demirel, Ipek Süntar*

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Activity Methods for Polycystic Ovary Syndrome

- Pp. 200-228 (29)
Murside Ayse Demirel, Kevser Taban Akça, Sümeyra Çetinkaya, Ipek Süntar*

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Methods for Studying the Activity of Natural Extracts on Renal Transporters İnvolved in the Regulation of Blood Pressure

- Pp. 229-244 (16)
Andrea Gerbino*, Monica Carmosino*

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Activity Methods for Cardiovascular System Diseases

- Pp. 245-279 (35)
Rosangela Montanaro, Emma Mitidieri, Roberta d’ Emmanuele di Villa Bianca, Vincenzo Brancaleone*

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Activity Methods For Animal Pharmacokinetic and Pharmacodynamic Studies

- Pp. 280-292 (13)
Rosangela Montanaro, Francesco Maione, Vincenzo Brancaleone*

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Subject Index

- Pp. 293-297 (5)
Ipek Suntar, Davide Barreca, Luigi Milella
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