Editors: Dilvani Oliveira Santos, Paulo Renato Zuquim Antas

Series Title: Frontiers in Inflammation

Mitochondrial DNA and the Immuno-inflammatory Response: New Frontiers to Control Specific Microbial Diseases

Volume 3

eBook: US $39 Special Offer (PDF + Printed Copy): US $72
Printed Copy: US $52
Library License: US $156
ISSN: 2468-1466 (Print)
ISSN: 2468-1474 (Online)
ISBN: 978-981-5051-70-4 (Print)
ISBN: 978-981-5051-69-8 (Online)
Year of Publication: 2022
DOI: 10.2174/97898150516981220301

Introduction

Mitochondria are multifunctional organelles that actively participate in the immune-inflammatory response in various pathologies. This volume updates readers on knowledge about mitochondria function. The editors have compiled six chapters about inflammation in its broadest sense, with contributions from active groups of cell biologists, infectologists and pathologists.

The chapters in this volume focus on research related to five notable diseases:

(1) two diseases (one bacterial and one viral) in which the exacerbation of the inflammatory response can lead to neuropathies: leprosy (one of the oldest diseases in the world) and Zika fever (a disease relatively new in Brazil)

(2) three diseases (two bacterial and one viral) in which the exacerbation of the inflammatory response can lead to irreversible lung damage that can cause rapid death: tuberculosis, pneumonia and the most recent global disease, COVID- 19.

New information about mitochondrial biology is presented, such as the effect of aerobic physical exercise as a stimulator for mitochondria multiplication, and the role of mitochondrial damage in inducing immune-inflammatory responses to pathogens. The contents shed light on mitochondrial biochemical pathways that could serve as potential therapeutic targets.

This is an important reference for scholars (cell biologists, microbiologists) in universities, hospitals and scientific research centers working on biological and biomedical problems, and for health professionals involved in infection control.

Audience: Scholars (cell biologists, microbiologists) in universities, hospitals and scientific research centers working on biological and biomedical problems; health professionals involved in infection control.

Contributors

Editor(s):
Dilvani Oliveira Santos
Postgraduate Program in Applied Microbiology and Parasitology of the University and Postgraduate Program in Science and Biotechnology University Federal Fluminense (UFF)
Niterói, RJ
Brazil


Paulo Renato Zuquim Antas
Clinical Immunology Laboratory/ Postgraduate Program in Tropical Medicine/ Oswaldo Cruz Foundation
Manguinhos, RJ
Brazil




Contributor(s):
Alessandra D' Almeida Filardy
Department of Immunology
Institute of Microbiology Paulo de Góes, Federal University of Rio de Janeiro
Rio de Janeiro, RJ
Brazil


Analúcia Rampazzo Xavier
Multiuser Laboratory for Research Support in Nephrology and Medical Sciences
Faculty of Medicine, University Federal Fluminense, Niterói
Rio de Janeiro, RJ
Brazil
/
Department of Pathology
Faculty of Medicine, University Federal Fluminense, Niterói
Rio de Janeiro
Brazil


Andrea Alice Silva
Multiuser Laboratory for Research Support in Nephrology and Medical Sciences
Faculty of Medicine, University Federal Fluminense, Niterói
Rio de Janeiro, RJ
Brazil
/
Department of Pathology
Faculty of Medicine, University Federal Fluminense, Niterói
Rio de Janeiro
Brazil


Anna Fernandes Silva Chagas do Nascimento
Postgraduate Program in Applied Microbiology and Parasitology of the University Federal Fluminense (UFF)
Niterói
Rio de Janeiro
Brazil


Arthur Willkomm Kazniakowski
Faculty of Pharmacy, University Federal Fluminense (UFF)
Niterói
Rio de Janeiro
Brazil


Débora Familiar-Macedo
Laboratory of Viral Immunology
Oswaldo Cruz Foundation
Rio de Janeiro
Brazil


Dilvani Oliveira Santos
Postgraduate Program in Applied Microbiology and Parasitology of the University Federal Fluminense (UFF)
Niterói
Rio de Janeiro
Brazil
/
Postgraduate Program in Science and Biotechnology (PPBI)/Institute of Biology
Federal Fluminense University (UFF)
Niterói, Rio de Janeiro
Brazil


Fabiana Rabe Carvalho
Multiuser Laboratory for Research Support in Nephrology and Medical Sciences
Faculty of Medicine, University Federal Fluminense, Niterói
Rio de Janeiro, RJ
Brazil


Felipe Piedade Gonçalves Neves
Department of Microbiology and Parasitology, Biomedical Institute
University Federal Fluminense
Niterói
RJ, Brazil


Laura Brandão Martins
Biomedical Institute, University Federal Fluminense (UFF)
Niterói
Rio de Janeiro
Brazil


Maria Elena Samar
Department of Oral Biology, Faculty of Dentistry
National University of Cordoba
Cordoba
Argentina


Paulo Renato Zuquim Antas
Clinical Immunology Laboratory
Oswaldo Cruz Foundation
Manguinhos, RJ
Brazil
/
Postgraduate Program in Tropical Medicine
Oswaldo Cruz Foundation
Manguinhos, RJ
Brazil


Rodolfo Avila
Department of Cell Biology and Histology, Faculty of Medical Sciences
National University of Cordoba
Cordoba
Argentina


Sourou Credo Francisco Justus Zinsou
Biomedical Institute, University Federal Fluminense (UFF)
Niterói
Rio de Janeiro
Brazil


Tatiana de Castro Abreu Pinto
Department of Medical Microbiology
Institute of Microbiology Paulo de Góes, Federal University of Rio de Janeiro
Rio de Janeiro, RJ
Brazil


Thalia Medeiros
Multiuser Laboratory for Research Support in Nephrology and Medical Sciences
Faculty of Medicine, University Federal Fluminense, Niterói
Rio de Janeiro, RJ
Brazil