Editors: Sanket Kaushik, Nagendra Singh

Current Developments in the Detection and Control of Multi Drug Resistance

eBook: US $49 Special Offer (PDF + Printed Copy): US $83
Printed Copy: US $59
Library License: US $196
ISBN: 978-981-5049-88-6 (Print)
ISBN: 978-981-5049-87-9 (Online)
Year of Publication: 2022
DOI: 10.2174/97898150498791220101


The rise in the incidence of infections is caused by multi drug resistant (MDR) bacteria, it is essential to elucidate the basic mechanism of antibiotic resistance to discover effective methods for diagnosis and treatment of infections.

The use of pathogen-specific probes offers a faster alternative for pathogen detection and could improve the diagnosis of infection. High resolution melting analysis techniques are useful for the detection of multi drug resistant pathogens. Rational Structural Based Drug Design is a common method to identify a lead compound and take it forward for further developments.

This book provides information about recent strategies involved in the diagnosis and treatment of infections caused by MDR bacteria. The volume covers the use of molecular probes for the quantification of pathogenic bacteria, along with other techniques mentioned above. Chapters also cover the use of identification of novel drug targets from the Lipid A biosynthesis and also from quorum sensing mediated biofilm formation in MDR bacteria.

Chapters also cover herbal alternatives for the treatment of MDR bacteria like the use of Cassia aungustifolia in treatment of various diseases. The reference is suitable for biomedical students, cellular and molecular biologists.

Audience: Pharmaceutical Scientists, Students of microbiology and pharmacology


The ability of different species of bacteria to resist the antimicrobial agent has become a global problem. Despite the development of so many antibiotic molecules during the last fifty years, increasing antibiotic resistance worldwide may lead to therapeutic dead-end. The disease burden from multidrug-resistant strains of organisms causing AIDS, tuberculosis, gonorrhoea, malaria, influenza, pneumonia, and diarrhoea is being felt in both the developed and the developing countries alike. This book summarizes the emerging trends in the field of antibiotic resistance of various MDR bacterial species.

Current strategies of detection and control of multidrug resistant bacteria provides the clear and recent information regarding strategies involved in diagnosis and treatment of MDR bacteria. Over the past decades, due to the exponential rise in the infections caused by MDR bacteria, it is necessary to elucidate the basic mechanism of antibiotic resistance to find out the effective methods for treatment and control. Primary goal of this book is to elaborate and enhance the theoretical knowledge of bacterial pathogenesis, diagnosis and treatment. It concentrates on further elaboration of current strategies of detection and control of MDR bacteria, Quantification of pathogenic bacteria, High Resolution Melting Analysis techniques, Biosynthesis pathways and Rational structure based drug design for MDR infections.

We have attempted to provide large amount of information in each chapter supplemented with in- depth knowledge of current strategies of detection and control of MDR bacteria. This book enhances the knowledge of Microbiology, Biotechnology and Life sciences in field area of MDR pathogenesis and control. The idea to encompass knowledge spanning from what is known to what is unknown in the writings from the experts in the field will result in a rigorous effort to justify the various topics.

We strongly believe that this book will be reader’s delight providing comprehensive understanding of diagnosis and treatment of MDR bacteria. It will be an ideal resource for student’s better understanding of MDR bacteria biology and useful for biomedical students, cellular and molecular biologists. I hope you will find this book interesting and relevant.

Sanket Kaushik
Amity Institute of Biotechnology
Amity University Rajasthan
Jaipur- 303002, India


Nagendra Singh
School of Biotechnology
Gautam Buddha University
Greater Noida- 201308, India