Editors: Sanket Kaushik, Nagendra Singh

Current Developments in the Detection and Control of Multi Drug Resistance

eBook: US $49 Special Offer (PDF + Printed Copy): US $83
Printed Copy: US $59
Library License: US $196
ISBN: 978-981-5049-88-6 (Print)
ISBN: 978-981-5049-87-9 (Online)
Year of Publication: 2022
DOI: 10.2174/97898150498791220101


The rise in the incidence of infections is caused by multi drug resistant (MDR) bacteria, it is essential to elucidate the basic mechanism of antibiotic resistance to discover effective methods for diagnosis and treatment of infections.

The use of pathogen-specific probes offers a faster alternative for pathogen detection and could improve the diagnosis of infection. High resolution melting analysis techniques are useful for the detection of multi drug resistant pathogens. Rational Structural Based Drug Design is a common method to identify a lead compound and take it forward for further developments.

This book provides information about recent strategies involved in the diagnosis and treatment of infections caused by MDR bacteria. The volume covers the use of molecular probes for the quantification of pathogenic bacteria, along with other techniques mentioned above. Chapters also cover the use of identification of novel drug targets from the Lipid A biosynthesis and also from quorum sensing mediated biofilm formation in MDR bacteria.

Chapters also cover herbal alternatives for the treatment of MDR bacteria like the use of Cassia aungustifolia in treatment of various diseases. The reference is suitable for biomedical students, cellular and molecular biologists.

Audience: Pharmaceutical Scientists, Students of microbiology and pharmacology


- Pp. i
Sanket Kaushik, Nagendra Singh
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List of Contributors

- Pp. ii-iii (2)

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- Pp. 1-5 (5)
Sanket Kaushik, Nagendra Singh*
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Development of Drug Resistance

- Pp. 6-12 (7)
Divyapriya Karthikeyan, Mukesh Kumar, Jyoti Yadav, Amit Alok, Kishore K. R. Tetala, Sanjit Kumar*
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Current Challenges in Treating MDR

- Pp. 13-32 (20)
Vaishali Gurjar, Ayushi Khurana, Gunjan Shaily, Sanket Kaushik, Nagendra Singh*
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Methods of Detection of MDR

- Pp. 33-42 (10)
Monish Bisen, Anupam Jyoti, Juhi Saxena*
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Molecular Probes as Diagnostic Tools

- Pp. 43-49 (7)
Anurag Jyoti*, Rajesh Singh Tomar
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Real-Time PCR High-Resolution Melting Analysis

- Pp. 50-65 (16)
Ena Gupta, Sanket Kaushik, Vijay Kumar Srivastava, Juhi Saxena, Anupam Jyoti*
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Current Therapeutic Options and Challenges for MDR

- Pp. 66-78 (13)
Aakanksha Kalra, Sakshi Piplani, Ravi Ranjan Kumar Niraj*
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Phytomedicines for Bacterial Infections

- Pp. 79-88 (10)
Vijay Pal, Ravneet Chug, Kumar Sambhav Verma, Priyal Sharma, Vinod Singh Gour*
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Molecular Mechanisms of Antimicrobial Resistance and New Targets to Address Current Drug Resistance

- Pp. 89-125 (37)
Divyapriya Karthikeyan, Sudhir Kumar Pal, Mukesh Kumar, Kali Kishore Reddy Tetala, Punit Kaur, Sanjit Kumar*
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Drug Discovery for MDR

- Pp. 126-140 (15)
Jyoti Yadav, Nagendra Singh, Anupam Jyoti, Vijay Kumar Srivastava, Vinay Sharma, Sanket Kaushik*
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Recent Developments to Fight Multidrug Resistance (MDR) in Protozoa

- Pp. 141-156 (16)
Mrinalini Roy, Sanket Kaushik, Anupam Jyoti, Vijay Kumar Srivastava*
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Subject Index

- Pp. 157-167 (11)

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