Editor: Tabish Qidwai

Neurodegenerative Diseases: Multifactorial Degenerative Processes, Biomarkers and Therapeutic Approaches

eBook: US $79 Special Offer (PDF + Printed Copy): US $126
Printed Copy: US $87
Library License: US $316
ISBN: 978-981-5040-92-0 (Print)
ISBN: 978-981-5040-91-3 (Online)
Year of Publication: 2022
DOI: 10.2174/97898150409131220101


This reference is the definitive guide to common neurodegenerative diseases that affect humans. The book covers mechanisms of some of the most well-known neurodegenerative diseases, their biomarkers, neuropharmacology, and emerging treatment strategies.

The book introduces the subject of neurodegeneration by outlining the biochemistry, pathophysiology and multifactorial neurological mechanisms (the role of genetics, environmental factors and mitochondrial damage, for example). Next, it explains some of the most studied diseases, namely, Parkinson’s Disease, Alzheimer’s Disease, Huntington’s Disease, and Multiple Sclerosis. Subsequent chapters delve into current knowledge about diagnostic and immunological biomarkers, followed by a summary of novel therapeutic strategies.

Special attention has been given to the role of medicinal plants in attempting to treat neurodegenerative diseases, as well as the public health burden posed by these conditions.

Key Features:

  • - give readers an overview of multifactorial disease mechanisms in neurodegeneration
  • - covers some major neurodegenerative diseases in detail
  • - covers diagnostic and immunological biomarkers
  • - explores current therapeutic strategies and drug targets in common neurodegenerative diseases
  • - offers a simple presentation with references for advanced readers

The book is a suitable reference for all readers, including students, research scholars, and physicians who are interested in the mechanisms and treatment of neurodegenerative diseases.

Audience: Students, research scholars, and physicians who are interested in the mechanisms and treatment of neurodegenerative diseases.


- Pp. i
Tabish Qidwai*
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List of Contributors

- Pp. ii-iii (2)

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Neurodegenerative Diseases Involve Multifactorial Interplay of Genetics and Environmental Factors

- Pp. 1-12 (12)
Tabish Qidwai*
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Colligation of Mitochondria Dysfunction and Neurodegeneration: Parkinson’s Disease

- Pp. 13-25 (13)
K Amrutha, Neelam Yadav, Sarika Singh*
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Protein Aggregation in Neurodegenerative Diseases

- Pp. 26-58 (33)
Rishabh Chaudhary, Mujeeba Rehman, Vipul Agarwal, Arjun Singh Kaushik, Vikas Mishra*
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Role of Reactive Oxygen Species in Neurodegenerative Diseases

- Pp. 59-70 (12)
Sukanya Tripathy, Sanjay Singh, Monisha Banerjee, Anand Prakash*
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Parkinson Disease: Molecular Biology, Pathophysiology and Biomarkers

- Pp. 71-87 (17)
Sarfraj Ahmad Siddiqui, Habiba, Md Arshad*
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Alzheimer’s Disease: Molecular Biology, Pathophysiology and Biomarkers

- Pp. 88-98 (11)
Yoganchal Mishra, Sarika Singh, Neelam Yadav*
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Huntington's Disease: Molecular Basis, Pathophysiology and Biomarker

- Pp. 99-114 (16)
Sarfraj Ahmad Siddiqui*, Anand Prakash
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Multiple Sclerosis: Molecular Biology, Pathophysiology and Biomarkers

- Pp. 115-124 (10)
Sanjay Singh*, Sukanya Tripathy, Anand Prakash
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Molecular Diagnostics and Immunological Markers of Neurodegenerative Disorders

- Pp. 125-142 (18)
Subhadip Chakraborty*
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Omics for Biomarker Investigation in Neurodegenerative Diseases

- Pp. 143-160 (18)
Aiman Tanveer*, Dinesh Yadav
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Emerging Therapeutic Approaches for Neurodegenerative Diseases

- Pp. 161-198 (38)
Rajesh R. Ugale*, Lopmudra Sarode
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Medicinal Plants and Natural Compounds as Antiparkinsonian Agents

- Pp. 199-217 (19)
Walia Zahra, Hareram Birla, Saumitra Sen Singh, Aaina Singh Rathore, Hagera Dilnashin, Richa Singh, Priyanka Kumari Keshri, Surya Pratap Singh*
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Neuropharmacology in Alzheimer and Huntington Disease

- Pp. 218-260 (43)
Bandna Gupta*, Kopal Rohatgi
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Brief Description of Public Health and Burden of Neurodegenerative Diseases

- Pp. 261-272 (12)
Vandana Ranjan*, Aisha, Kalpna Verma
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Subject Index

- Pp. 273-289 (17)

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.Frontiers in Clinical Drug Research - CNS and Neurological Disorders.
.Frontiers in Clinical Drug Research - CNS and Neurological Disorders.
.Frontiers in Clinical Drug Research - CNS and Neurological Disorders.