Foreword

Drug discovery and drug development nowadays are growing very fast by using new tools and advanced techniques of modern science. Drugs are being synthesized or obtained from natural sources, including marine sources, to get lead molecules. Every such molecule needs to be evaluated in terms of safety and efficacy before it is actually being used for mankind.

Animal models are a basic essential tool to prove the safety and efficacy of any drug molecule in experimental neuroscience. Therefore, the selection of a suitable and reliable experimental model becomes essential. Every experimental model has its own potential advantages and limitations in order to study disease pathologies, and therefore, increasingly, various emerging tools and techniques are being used in addition to it. It becomes imperative for every researcher to be able to select suitable animal models and have an in-depth knowledge of their advantages or limitations while studying disease pathologies.

I am confident that the present book serves the purpose of various researchers working in the areas of neurological problems, in particular Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, depression, autism, etc., to understand the various aspects of these experimental models and their potential use to study disease pathologies. The present book has been written with a purpose to provide various key insights related to pathophysiology, experimental (invivo and invitro) techniques, advantages, disadvantages, limitations, including future prospective of various experimental models such as Alzheimer, depression, psychosis, Parkinson, vascular dementia, multiple sclerosis, schizophrenia, autism, Huntington disease and brain tumor model based on researcher’s laboratory experience. Biomedical researchers will further benefit from the rich research experiences of the authors working in the areas of neurological problems. Lastly, I would like to commend Prof. Anil Kumar on this brilliant effort.