Preface

In recent times, research on drugs for burn wounds is considered an emerging area of interest in modern healthcare domain. Researchers who are seeking to discover novel therapeutics from natural supplies are looking towards herbal medicine. Injuries due to burning are notable causes of death and morbidity and burn therapy normally expects prolonged hospitalization and rehabilitation, which may lead to higher health care costs. Therefore, burn wounds are one of the global health problems and socio-economic factors. An infection has continually been one of the important concerns of burn wound management. Burn wound infections can create severe difficulties, such as the production of wound exudates, retardation and delayed wound healing and deposition of inappropriate collagen. The purpose of burn wound care management is speedy wound healing and epithelization to limit the infection. The topical application of burn therapy is quintessential for the longevity of patients with significant burns by reducing the risks of burn wound sepsis in these cases.

Moreover, in the current epoch, the approaches for the treatment of burns employing the available drug delivery tools have been highly thwarted. With the involvement of intricate etiology and progression of the burn wound, the reliance on the available therapy as well as delivery systems is therapeutically less effective. In recent times, the research on herbal medicine has vastly increased because of their safe toxicological profiles in contrast to synthetic medicines. Natural products and their derivatives represent more than 50% of all the drugs in modern therapeutics. Over the past few decades, scientists have focused on drug discovery from plant medicines. Despite the promising therapeutic potential of herbal medicines, poor biopharmaceutical characteristics, including solubility, permeability, stability, lack of targetability, a high degree of off-target side effects, etc., hamper their clinical application. In this regard, the nanotechnology-based smart drug delivery approach can help to overcome these biopharmaceutical challenges. The current research reports are a witness of the verity of versatile applications of minuscule size nanocarriers to become the next generation treatment tools.

The objectives of the present book are to provide readers an abridged set of information on plant-mediated metallic nanoparticulate systems and nanophytomedicine based therapeutic treatment modalities for burn wound lesions. This book will be expected to deliver an updated piece of recent information and know-how to the scientists and researchers working in the field of nanomedicines based burn wound therapy. The book has been divided into nine chapters.

The first chapter provides an update on the current and future outlook of nanomedicine based treatment modalities for burn wound lesions. The second chapter highlights the importance of nanotechnology in the development of nanocarrier based phytmoedicines for burn wound treatment, including burn wound healing. The third and fourth chapters enlighten the “phyto-assisted synthesis of silver nanoparticles and its role in the management of burn wound infection. The fifth chapter describes the phytochemical-assisted gold nanoparticles potential in burn wound management. The sixth chapter provides an overview of the phytochemical-assisted zinc oxide nanoparticles synthesis approach and its potential in burns. The seventh chapter focuses on plant mediated synthesis of Titanium dioxide Nanoparticles for burn wound management. The eighth chapter provides a brief outline on phytochemical-assisted metallic nanoparticles toxicity in burn wound therapy. The last chapter discusses a novel herbal informatics approach for the management of skin burn injury.