Editors: Deepak Kaushik, Ravinder Verma

A Comprehensive Text Book on Self-emulsifying Drug Delivery Systems

eBook: US $69 Special Offer (PDF + Printed Copy): US $117
Printed Copy: US $83
Library License: US $276
ISBN: 978-981-4998-01-7 (Print)
ISBN: 978-981-4998-00-0 (Online)
Year of Publication: 2021
DOI: 10.2174/97898149980001210101

Introduction

This text book is a guide for pharmaceutical academics (students and teachers) as well as industry professionals learning about drug delivery and formulation. Chapters presents comprehensive information about self-emulsifying formulations by providing an in-depth understanding of the basic concepts and formulation mechanisms. This information is supplemented by details about current research and development in this field. Readers will learn about the types of self-emulsifying drug delivery systems, evaluation parameters and digestion models, among other topics.

Key Features:

- 9 chapters organized in a reader-friendly layout

- complete guide on self-emulsifying drug delivery formulations, including lipid based systems, SMEDOs, surfactants, and oral dosage forms

- includes basic concepts and current developments in research and industrial applications

- presents information on conventional and herbal formulations

- references for further reading

Foreword

Self-emulsifying drug delivery system (SEDDS) is a significant approach for improving the rate and extent of absorption of hydrophobic or lipophilic drugs that come under class II and IV of the Biopharmaceutical Classification System (with low solubility), and exhibits a dissolution rate-limited absorption. SEDDS formulations lead to increased drug solubility and bioavailability, avoidance of food effect, and enhanced environmental degradation stability. Enhanced oral bioavailability allows dose reductions and high efficiency of drug release. In the gastrointestinal tract (GIT), self-emulsifying formulations spread readily, and the digestive motility of the stomach and intestine provides the stimulation required for self-emulsification.

This reference book on SEDDS specifically addresses the basic aspects and current research going on in this field. In the following nine chapters, various authors give a comprehensive review of SEDDS, covering the basic components and latest advances such as solid-SMEDDS, herbal SEDDS formulations along with discussions on pharmacokinetic and in vitro digestion models for estimation of SEDDS.

The book is an excellent reference work for academicians, students, pharmaceutical industry professionals as well as research scientists involved in the investigation and development of SEDDS.


Arun Nanda
Department of Pharmaceutical Science
M.D.University, Rohtak
India

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