Bioactive Phytochemicals: Drug Discovery to Product Development

Editors: Javed Ahmad, Javed Ahamad

Bioactive Phytochemicals: Drug Discovery to Product Development

ISBN: 978-981-14-6446-1
eISBN: 978-981-14-6448-5 (Online)

Introduction

Natural bioactive compounds from medicinal plants are inexplicably diverse in chemical structure and biological properties. The unmet therapeutic requirements for various diseases serve as a guide for researchers to study natural compounds. These studies are intended to isolate, identify the structural characterization and eventually discover the pharmacological activity of natural compounds from their plant sources with the goal of treating specific diseases.

Bioactive Phytochemicals: Drug Discovery to Product Development explores the scope and approaches of drug discovery from natural products. Chapters in the book cover information about the cultivation, collection and processing of medicinal plants, the methods and high throughput techniques for isolation and characterization of bioactive phytochemicals and pharmacological screening for activity, formulation and quality control. Information about the regulations specified for natural medicinal products in different region of the world is also presented, followed by a concluding chapter devoted to the role of natural herbal products for treatment of human diseases such as cancer, cardiovascular diseases, diabetes, obesity, inflammation and neurological disorders. Each chapter concludes with a general reference section, which is a bibliographic guide to more advanced texts. The contributing authors for this volume are drawn from a rich blend of experts in various areas of herbal medicine which encompass herbal drug discovery to product development.

The concise and organized layout along with a broad coverage of phytochemistry and drug discovery makes this book a suitable reference for students of medicinal chemistry, researchers and industry professionals interested in herbal product development.

Foreword

Plants have always considered been as ‘Nature’s Library’ for new chemical entities and one of the major resources in drug discovery and new drug development. Medicinal plants that have been used in traditional systems of medicine are being studied more than a fine decade for scientific evaluation and validation of the application, which provides rational and evidence-based alternative medicines and eventually a backbone of modern day’s herbal drug, herbal bioactives, semisynthetic and to some extent in synthetic drug and pharmaceutical industries.

In the light of the foregoing, this Book, "Bioactive Phytochemicals: Drug Discovery to Product Development" is a tremendously important and in-depth contribution to the subject of ’Phyto-pharmaceuticals from drug discovery to product development’. The book has brought together diverse works in the scientific literature under an umbrella on the use of therapeutically active phytochemicals in the treatment of various chronic disorders. An excellent effort has been made in this frankly speaking 'a much-needed book' to address the challenges in plant and plant bioactive based drug development to its transition to the phytopharmaceutical product comprehensively and sequentially. I am confident that the book is capable of centering the attention of the reader on the limitless potentials of bioactive phytochemicals. It does particularly well too in highlighting several current areas of interest in extraction, isolation, structural characterization, pharmacological screening, product development and regulatory perspectives of herbal drugs and bioactive phytochemicals

I have, no doubt, that this book will be well-received (equally) by the researchers in the phytopharmaceutical industry and academia. Moreover, this book is really good at offering a vast knowledge on this subject to the chemist and pharmacy students.

Dr. Sohail Akhter
Global R & D
Teva Pharmaceuticals
Runcorn
United Kingdom


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