Editors: Shankar Suman, Garima Suman, Sanjay Mishra

Current Advances in Breast Cancer Research: A Molecular Approach

eBook: US $99 Special Offer (PDF + Printed Copy): US $168.5
Printed Copy: US $119
Library License: US $396
ISBN: 978-981-14-5142-3 (Print)
ISBN: 978-981-14-5144-7 (Online)
Year of Publication: 2020
DOI: 10.2174/97898114514471200101

Introduction

Breast cancer is a recognized disease around the world with varying patient outcomes based on the type of breast cancer, access to healthcare and other factors. Survival rates for breast cancer are significantly lower in metastatic cases than localized cases. Early diagnosis and effective treatments for the efficient management of breast cancer are now in demand , as they help to prolong patient life. There have been many breakthrough developments in the molecular biology of breast cancer research in recent times. Advancements in diagnostic techniques (imaging and biomarker detection) for breast cancer have improved the screening of the disease and have improved patient outcomes. Despite these enhancements, the disease is still lethal for patients and the search for a cure requires a complete understanding of the disease.

Current Advances in Breast Cancer Research: A Molecular Approach presents a comprehensive overview of current basic and translational research on the subject. The 14 chapters of the book give emphasis to current knowledge about breast cancer, ongoing challenges, and innovative research findings by different research groups. Readers will find detailed information about breast cancer biology, genetics, clinical diagnostics and treatments. Additional information for advanced readers in life sciences, such as techniques relevant to genomics (including genetic fingerprinting), proteomics, metabolomics and medicine (such as imaging and molecular diagnostics) is also provided. The combination of both basic and advanced information makes this book a useful reference to the student and researcher, alike, seeking an understanding about breast cancer at a molecular level.

Foreword

- Pp. i
Smita Misra
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Preface

- Pp. ii
Shankar Suman, Garima Suman and Sanjay Mishra
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List of Contributors

- Pp. iii-iv (2)
Shankar Suman, Garima Suman and Sanjay Mishra
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Breast Cancer: A Global Burden

- Pp. 1-29 (29)
Brij Nath Tewari and Sanjay Mishra

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Current Imaging Techniques in Breast Cancer: An Overview

- Pp. 30-60 (31)
Garima Suman and Anurima Patra

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An Overview of Genetic, Proteomic and Metabolomic Biomarkers in Breast Cancer

- Pp. 61-103 (43)
Tarjani Agrawal

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Recent Proteomics Development for Biomarker Detection in Breast Cancer

- Pp. 104-122 (19)
Gatha Thacker

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Deregulation of Enzymatic Post-Translational Modifications in Breast Cancer

- Pp. 123-138 (16)
Lokesh Baweja, Neha Rajoria and Shankar Suman

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Genomic Fingerprint of Molecular Mechanisms of Breast Carcinogenesis

- Pp. 139-177 (39)
Akanksha Nigam and Shivam Priya

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Perspectives of Deregulated Metabolism in Breast Cancer

- Pp. 178-207 (30)
Shankar Suman

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Oxidative Stress and Lifestyle-based Changes in Breast Cancer Progression

- Pp. 208-235 (28)
Vipendra K. Singh and Pradeep K. Sharma

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Epithelial-Mesenchymal Transition (EMT) in Breast Cancer: An Overview

- Pp. 236-253 (18)
Manish Charan, Bhavana Kushwaha, Sanjay Mishra and Ramesh K Ganju

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miRNA Biology in Breast Cancer Progression

- Pp. 254-277 (24)
Sanjay Mishra, Manish Charan, Swati Misri, Dinesh Ahirwar and Ramesh K. Ganju

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Calcium Signaling in Breast Cancer: Current Perspective

- Pp. 278-304 (27)
Manuraj Pandey, Akanksha Nigam and Rajendra Mehta

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Role of Mitochondrial-mediated Pathways in Breast Cancer: An Overview

- Pp. 305-327 (23)
Nabanita Chatterjee, Debangshi Das, Ashna Jha and Sraddhya Roy

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Advances of the Current Therapeutic Approach for the Management of Breast Cancer

- Pp. 328-345 (18)
Saroj Kumar Amar, Ajeet Kumar Srivastav and Swayam Prakash Srivastava

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Micro and Nano-scale Technologies for Breast Cancer Detection and Destruction

- Pp. 346-368 (23)
Pranay Agarwal

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Subject Index

- Pp. 369-382 (14)
Shankar Suman, Garima Suman and Sanjay Mishra
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