Editors: Atta-ur-Rahman, M. Iqbal Choudhary

Applications of NMR Spectroscopy

Volume 8

eBook: US $69 Special Offer (PDF + Printed Copy): US $153.5
Printed Copy: US $119
Library License: US $276
ISSN: 2405-4674 (Print)
ISSN: 2405-4682 (Online)
ISBN: 978-981-14-3383-2 (Print)
ISBN: 978-981-14-3997-1 (Online)
Year of Publication: 2020
DOI: 10.2174/97898114399711200801


Applications of NMR Spectroscopy is a book series devoted to publishing the latest advances in the applications of nuclear magnetic resonance (NMR) spectroscopy in various fields of organic chemistry, biochemistry, health and agriculture.

The eighth volume of the series features six reviews focusing on NMR spectroscopic techniques in food science, molecular biology and medical diagnosis. The reviews in this volume are:

- qNMR as a Tool for Determination of Six Common Sugars in Foods

- Correlation of VIP Scores and 1H NMR to Extract Information of Psychological Attention Tests Applied Before and After Coffee Intake

- NMR Spectroscopy for Probing the Structural Determinants of Aptamer Optimization and Riboswitch Engineering

- Applications of NMR Spectroscopy in Medical Diagnosis

- Applications of NMR Spectroscopy in Cancer Diagnosis

- NMR as a Tool for Exploring Protein Interactions and Dynamics


Nuclear Magnetic Resonance (NMR) spectroscopy has emerged as one of the most powerful techniques for the identification of materials, and for the study of their dynamic properties. As a result, the technique has found tremendous uses in almost all fields of physical, natural, and health sciences.

Volume 8 of the book series entitled Applications of NMR Spectroscopy is mainly focussed on the practical uses of NMR spectroscopy in solving various key problems in biomedical, health, and food sciences. The contents include NMR based analysis of common sugars, plant based constituents, nucleic acids and proteins, as well as NMR- based metabolomics and MRI for the diagnosis of chronic and acute health disorders.

The review contributed by Yang et al. provides an overview of the use of quantitative NMR (qNMR) techniques for the analysis of six common sugars in complex food matrices, after derivatization with naphthimidazole (NAIM). Coffee plants contain many constituents which effect cognitive functions. Valderrama et al. have analysed the constituents of various coffee types, and correlated them through the use of the psychological attention test. Evran et al. have reviewed the recent literature on the NMR-based structures of aptamers (single stranded DNA and RNA molecules) selected via an iterative process called Systematic Evolution of Ligands by Exponential Enrichment (SELEX). The applications of NMR for the identification of the ligand binding mechanisms are discussed. The review contributed by Ibrahim and Gopalsamy describes various NMR techniques used in metabolomics-based diagnosis of common diseases. The next chapter by Asmaa and Mansour provides a critical analysis of various MRI-based diagnostic approaches to study diverse human cancers. Proteins are fascinating molecules, both because of their complex structures and their interactions with other biomolecules. NMR techniques have evolved over the years to determine the structures and functions of protein molecules. This is the key theme of chapter 6 by Bashir and Rashid.

We wish to thank all the eminent scientists for their scholarly contributions. The editorial team of Bentham Science Publishers, particularly Ms. Fariya Zulfiqar (Manager Publications) and team leader Mr. Mahmood Alam (Director Publications), deserves our deepest appreciation for compiling an excellent volume in a time efficient manner. We are confident that like the previous volumes of this book series, the current treatise will also receive wide appreciation for both the readers and practitioners of NMR spectroscopy.

Prof. Dr. Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Prof. Dr. M. Iqbal Choudhary
H.E.J. Research Institute of Chemistry
International Center for Chemical and Biological Sciences
University of Karachi


.Indicator Displacement Assays (IDAs): An Innovative Molecular Sensing Approach.
.Recent Advances in Analytical Techniques.
.Applications of NMR Spectroscopy.
.Advanced Techniques of Analytical Chemistry.