Sex Steroids and Apoptosis In Skeletal Muscle: Molecular Mechanisms


Andrea Vasconsuelo

DOI: 10.2174/97898114123631190101
eISBN: 978-981-14-1236-3, 2019
ISBN: 978-981-14-1235-6

This monograph focuses on the actions exerted by sex hormones, 17β-estradiol and testosterone, in skeletal muscle tissue. An important co...[view complete introduction]
US $
Buy Personal Book
Order Library Book
Order Printed Copy
Order PDF + Printed Copy (Special Offer)

*(Excluding Mailing and Handling)

🔒Secure Checkout Personal information is secured with SSL technology

Apoptosis As Cause Of Sarcopenia: Hormonal Regulation

- Pp. 127-143 (17)

Andrea Vasconsuelo


The muscle mass declines with age, affecting the independence in the elderly. This process known as sarcopenia and the acceleration of myocytes loss through apoptosis might signify the main causative. Skeletal muscle tissue increases its size and shows a notable capacity to adapt to injury, due the existence of an undifferentiated group of myogenic-specific precursor cells, called satellite cells. The knowledge of mechanism that driven the apoptosis in satellite cells represents an important base to understand the etiology of sarcopenia. This chapter centers on the potential impact that the estrogen- and testosteroneregulation of satellite cell function has in elderly skeletal muscle, highlighting in the role that both steroids have on apoptotic signaling in myoblasts.

Purchase Chapter  Book Details


Webmaster Contact: Copyright © 2019 Bentham Science