Editors: Ashita Sharma, Manish Kumar, Satwinderjeet Kaur, Avinash Kaur Nagpal

Evaluation of Environmental Contaminants and Natural Products: A Human Health Perspective

eBook: US $69 Special Offer (PDF + Printed Copy): US $153
Printed Copy: US $119
Library License: US $276
ISBN: 978-981-14-1095-6 (Print)
ISBN: 978-981-14-1096-3 (Online)
Year of Publication: 2019
DOI: 10.2174/97898114109631190101

Introduction

Unbridled urbanization and development of natural land resources has led to the degradation of our surrounding environment. The air that we breathe, the water we drink and the food we eat is at risk of being contaminated with a plethora of chemical pollutants, some of them being potentially carcinogenic. This presents a challenge to human health. This book attempts to address this challenge in two parts which represent two different approaches. The first part of the book summarizes the alarming effects of environmental contaminants. Various studies depicting the direct relationship of environmental contaminants with cancer incidence have been referenced. Scientific studies have established an inverse relation between cancer and ingestion of dietary phytoconstituents (phytochemicals) in the form of fruits, vegetables and botanical herbs. Plant products as dietary supplements can suppress contaminant toxicity by regulating the resulting reactive species and also by assisting their bodily excretion through Phase 1 and Phase 2 enzyme metabolism. The second part of the book, shifts focus to phytoconstituents which, if included in diet, can prevent the harmful effects of pollutants. The text references numerous studies showing the anti-mutagenic, anti-genotoxic and anti-carcinogenic potential of many plant products. The combination of information about contemporary issues of carcinogenic contaminants in the environment coupled with the references to relevant studies in this handbook will enlighten readers studying courses in environmental chemistry, toxicology, botany, and ecology about environmental toxins and help them understand specific dietary measures known to reduce the toxic impact. Researchers in the field of nutrition can also benefit from the information provided.

Preface

- Pp. i-ii (2)
Ashita Sharma and Manish Kumar
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Foreword

- Pp. iii
Renu Wadhwa
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List of Contributors

- Pp. vi-v (2)
Ashita Sharma and Manish Kumar
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Environmental Contaminants: Sources and Effects

- Pp. 1-23 (23)
Savita, Vivek Chopra and Anuradha Sharma

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Environmental Pollutants and Risk of Cancer

- Pp. 24-46 (23)
Indranil Chattopadhyay

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Toxicity of Environmental Contaminants: Use of Battery of Standard Biological Assays

- Pp. 47-64 (18)
Tajinder Kaur, Sneh Rajput, Gurpreet Kaur, Renu Bhardwaj and Saroj Arora

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Allium cepa Root Chromosomal Aberration Assay: A Tool to Assess Genotoxicity of Environmental Contaminants

- Pp. 65-93 (29)
Mandeep Kaur, Ashita Sharma, Rajneet Kour Soodan, Vanita Chahal, Vaneet Kumar, Jatinder Kaur Katnoria and Avinash Kaur Nagpal

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Pesticides: Problems and Remedial Measures

- Pp. 94-115 (22)
Sonal Yadav and Satyawati Sharma

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Biphenyls: Health Impacts and Toxicity Evaluation

- Pp. 116-137 (22)
Sakshi Sharma, Avinash Kaur Nagpal and Inderpreet Kaur

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Actinomycete Enabled Remediation Strategies: Potential Tool for Pollutant Removal from Diverse Niches

- Pp. 138-159 (22)
Anu Kalia, Sukhjinder Kaur and Madhurama Gangwar

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Role of Phytoconstituents in Modulating Xenobiotic Metabolism

- Pp. 160-192 (33)
Harsimran Kaur, Sandeep Kaur, Satwinderjeet Kaur and Paramjeet Kaur

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Potential Health Benefits of Nutraceuticals for Human Health

- Pp. 193-209 (17)
Sandeep Kaur, Manish Kumar, Kritika Pandit, Ajay Kumar and Satwinderjeet Kaur

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Caspases and Phytochemicals: An Important Link in Cancer Chemoprevention

- Pp. 210-243 (34)
Manish Kumar, Sandeep Kaur, Varinder Kaur and Satwinderjeet Kaur

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Understanding Molecular Diagnosis in Cancer

- Pp. 244-264 (21)
Trupti N. Patel and Priyanjali Bhattacharya

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Subject Index

- Pp. 265-276 (12)
Ashita Sharma and Manish Kumar
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