Preface

Breast cancer is the most frequent malignancy in women worldwide. It is associated with several risk factors including mutations, inheritance, and environmental factors. The heterogeneity in breast cancer cells shows the complexity of this disease. Despite newer day-to-day developments in cancer research, advanced breast cancer is still challenging to manage. The scientific innovation in breast cancer research has led to an increase in patient's overall survival in the last few decades. For example- the discovery of sensitive screening tools enhanced early-stage detection of breast cancer and further novel treatment regimens improved therapeutic benefits. The current research is also focused on developing new surgical modalities that are minimally invasive, and new radiation modalities with minimal side effects. This book is intended to target a broad audience who has an interest in breast cancer research and therapy. We have incorporated chapters delineating the recent studies on breast cancer with an emphasis on etiology, diagnosis, and therapy. Chapters uncover the new updated information on breast cancer signaling, immune-response, DNA damage, and epigenetic modifications with bioinformatics resources. The book will allow readers to review the data of numerous studies on immunotherapy and gene therapy as well. The latest concept on the use of nanotechnology in breast cancer, has also been reviewed in detail as nanotechnology has opened a paradigm shift in targeted drug delivery in breast cancer. The specific chapter also shows the importance of dietary polyphenol and its role in breast cancer. The application of radiotherapy in breast cancer is also well described, which will be helpful to gain the concept of clinical radiotherapy. In overall, chapters are organized to give the readers a practical and efficient way to familiarize themselves with the newest ongoing research in the field of breast cancer.