The Evolution of Radionanotargeting towards Clinical Precision Oncology: A Festschrift in Honor of Kalevi Kairemo

The Evolution of Radionanotargeting towards Clinical Precision Oncology is a remarkable book honoring Professor Kalevi Kairemo, who is known among academic and medical circles as a pioneer in novel radiolabeled therapeutics. This festschrift provides an overview of key advances in the field of radionanotargeting, and the directions for future development in patient care. Prof Kairemo’s research is based on multiomics, which involves multiple elements: genomics, transcriptomics, proteomics, metabolomics, microbiomics, epigenomics, exposome, imaging, and precision medicine, which is reflected by the unique collection of articles presented. The articles start from the angle of radionanotargeting and theragnostics leading to imaging and therapy, which includes sections for thyroid cancer, head and neck cancer, genitourinary cancers and neuroendocrine neoplasms. Theragnostics, nanoparticles and precision oncology have also been covered in their own segments, while also giving a glimpse of research in metabolic imaging, cardiovascular radionuclide imaging, and bone therapies. The sequence of chapters demonstrates how, through Professor Kairemo’s efforts, radionanotargeting has evolved to a practice changing therapeutic approach in the clinic, particularly in oncology. Finally, Professor Kairemo’s own memoir, “Seven decades in health care” and memoirs from colleagues including a personal introduction to him with a photographic cavalcade reveals the world of a multitasking person with a multidisciplinary approach to science, that ushered his development of significant expertise across the fields of chemistry, biology, engineering, physics and clinical medicine. This book is excellent for medical historians, trainees and specialists in clinical and radiological oncology in expanding their understanding of the role of radionuclide imaging over the years, making it an ideal tribute that belongs in the library of anyone involved in the field.

Editor(s):

Antti Jekunen

Contributor(s):

Aisyah Elliyanti
Medical Physics Department of Faculty of Medicine Universitas Andalas
Kampus Limau Manis, Padang, West Sumatra
Indonesia
/
Nuclear Medicine Installation of the Radiology Department of Dr.M.Djamil Hospital
Padang
Indonesia

Akseli Hemminki
Professor of Oncology, Cancer Gene Therapy Group, Translational Immunology Research Program
University of Helsinki
Helsinki
Finland
/
Helsinki University Hospital Comprehensive Cancer Center
Helsinki
Finland

Alexandra Nikaki
Department of Clinical Physiology and Isotope
Kanta-Häme Central Hospital
Hämeenlinna
Finland
/
Nuclear Medicine Department
University Hospital of Larissa
Larissa, Thessaly
Greece
/
PET/CT Department
Hygeia Hospital
Athens
Greece

Andrew M. Scott
Tumour Targeting Laboratory
Olivia Newton-John Cancer Research Institute
Melbourne
Australia
/
Department of Molecular Imaging and Therapy
Austin Health
Melbourne
Australia
/
School of Cancer Medicine
La Trobe University
Melbourne
Australia
/
Department of Medicine
University of Melbourne
Melbourne
Australia

Antti Jekunen
Professor in Clinical Oncology
Turku University
Finland
/
Chief Physician
Vaasa Oncology Clinic
Finland

Anne-Ségolène Cottereau
Médecine Nucléaire, Hôpital Tenon
AP-HP Sorbonne Université
Paris
France

Barbara Hertz

Dr. Saul Hertz Archives
Greenwich, CT
USA

Ben L. Feringa
Stratingh Institute for Chemistry
University of Groningen
Groningen
The Netherlands

Clare Senko
Tumour Targeting Laboratory
Olivia Newton-John Cancer Research Institute
Melbourne
Australia
/
Department of Molecular Imaging and Therapy
Austin Health
Melbourne
Australia

Erkki Hopsu
Chief Physician, ENT - Department
Kymenlaakso Central Hospital
Kotka
Finland

Erkki Koivunen
Professor, Molecular and Integrative Biosciences
University of Helsinki
Helsinki
Finland

Eve Kelk
Chief Physician in Nuclear Medicine, Clinic of Diagnostics Nuclear Medicine Centre
East Tallinn Central Hospital
Estonia

Finn Edler von Eyben
Center of Tobacco Control Research
Odense
Denmark

Françoise Montravers
Médecine Nucléaire, Hôpital Tenon
AP-HP Sorbonne Université
Paris
France

Georgios S. Limouris
Professor in Nuclear Medicine
National and Kapodistrian University
Athens-Hellas
Greece

Gert Luurtsema
Department of Nuclear Medicine and Molecular Imaging, Medical Imaging Center
University of Groningen, University Medical Center Groningen
Groningen
The Netherlands

Guus van Dongen
VUMC Imaging Center Amsterdam
Radiology & Nuclear Medicine
Amsterdam
The Netherlands

Hee-Seung Henry Bom
Professor, Chonnam National University Hwasun Hospital
Jeonnam
South Korea

Homer A. Macapinlac
Chair & Professor, Department of Nuclear Medicine
The University of Texas MD Anderson Cancer Center
Houston, Texas
USA

Hossein Jadvar
Associate Professor of Radiology, Urology, and Biomedical Engineering (Tenure)
Division of Nuclear Medicine and Molecular Imaging Center, Keck School of Medicine & Viterbi School of Engineering, University of Southern California
Los Angeles, CA,
USA

Hui K. Gan
Tumour Targeting Laboratory
Olivia Newton-John Cancer Research Institute
Melbourne
Australia
/
Department of Medical Oncology
Austin Health
Melbourne
Australia
/
School of Cancer Medicine
La Trobe University
Melbourne
Australia

Hugo Helbert
Department of Nuclear Medicine and Molecular Imaging, Medical Imaging Center
University of Groningen, University Medical Center Groningen
Groningen
The Netherlands
/
Stratingh Institute for Chemistry
University of Groningen
Groningen
The Netherlands

Ilya V. Sleptsov
North-West Centre of Endocrinology & Endocrine Surgery
St.Petersburg
Russia

Irene Virgolini
Department of Nuclear Medicine
Medical University of Innsbruck
Austria

Jean-Noël Talbot
Médecine Nucléaire, Hôpital Tenon
AP-HP Sorbonne Université
Paris
France

J Harvey Turner
The University of Western Australia
Fremantle
Australia

Jeja-Pekka Roos
Faculty of Common Matters
University of Helsinki
Helsinki
Finland

Joao M. Santos
Cancer Gene Therapy Group, Translational Immunology Research Program
University of Helsinki
Helsinki
Finland

Josh Mailman
Patient Advocate
NET
San Francisco, CA
USA

Jun Hatazawa
Department of Quantum Cancer Therapy
Research Center for Nuclear Physics, Osaka University
Osaka
Japan
/
Department of Nuclear Medicine and Tracer Kinetics
Osaka University Graduate School of Medicine
Osaka
Japan
/
Department of Nuclear Medicine in Osaka University Hospital
Osaka
Japan

Kalevi Kairemo
Department of Molecular Radiotherapy
Docrates Cancer Center
Helsinki
Finland
/
Department of Nuclear Medicine
The University of TexasMD Anderson Cancer Center
Houston, Texas
USA

Kishore Pillarsetty
Larson Lab, Molecular Pharmacology Program
Sloan Kettering Institutes, Memorial Sloan Kettering Cancer Center
New York, NY
USA

Linda Jorgov
Médecine Nucléaire, Hôpital Tenon
AP-HP Sorbonne Université
Paris
France
/
Department of Nuclear Medicine
Semmelweis University
Budapest
Hungary

Manoj Gupta
Nuclear Medicine
Rajiv Gandhi Cancer Center & Research Institute
Delhi
India

Marina Hodolic
Nuclear Medicine Research Department
IASON
Graz
Austria
/
Department of Nuclear Medicine, Faculty of Medicine and Dentistry
Palacký University Olomouc
Olomouc
Czech Republic

Markku Kangaspuro
Professor, Director, Aleksanteri Institute, Finnish Centre for Russian and East European Studies
University of Helsinki
Helsinki
Finland

Mike M. Sathekge
Department of Nuclear Medicine
University of Pretoria & Steve Biko Academic Hospital
Pretoria
South Africa
/
Nuclear Medicine Research Infrastructure (NuMeRI)
Steve Biko Academic Hospital
Pretoria
South Africa

Mikko Tenhunen
Head of Radiotherapy Department
Helsinki University
Helsinki
Finland

N.G. Seleva
A. Tsyb Medical Radiological Research Centre - branch of the National Medical Research
Radiological Centre of the Ministry of Health of the Russian Federation
Obninsk
Russia

Nigora Rasulova
Department of Nuclear Medicine
Republic Specialized Center of Surgery
Tashkent
Uzbekistan
/
Department of Nuclear Medicine
Farwaniya Hospital
Kuwait

Oula Penate Medina
Department of Radiology and Neuroradiology
University Medical Center Schleswig-Holstein, Kiel University
Kiel
Germany
/
MOIN CC - Institut für Experimentelle Tumorforschung
Kiel
Germany

Partha S. Choudhury
Director-Nuclear Medicine
Rajiv Gandhi Cancer Center & Research Institute
Delhi
India

Pavel Krzhivitskiy
Head of Nuclear Med. Department, Department of Radiotherapy and Nuclear Medicine
N.N. Petrov Institute of Oncology
St Petersburg
Russia

Petr Krivorotko
Surgery Department
N.N. Petrov Institute Oncology
St Petersburg
Russia

Philip H. Elsinga
Department of Nuclear Medicine and Molecular Imaging, Medical Imaging Center
University of Groningen, University Medical Center Groningen
Groningen
The Netherlands

Raluca Mititelu
Dept of Nuclear Medicine, Bucharest
Central Universitary Emergency Military Hospital "Dr Carol Davila"
Romanian Society of Nuclear Medicine
Romania

Rudi A. J. O Dierckx
Department of Nuclear Medicine and Molecular Imaging, Medical Imaging Center
University of Groningen, University Medical Center Groningen
The Netherlands

Sagun Parakh
Tumour Targeting Laboratory
Olivia Newton-John Cancer Research Institute
Melbourne
Australia
/
Department of Medical Oncology
Austin Health
Melbourne
Australia
/
School of Cancer Medicine
La Trobe University
Melbourne
Australia

Sang-Gyu Lee
Larson Lab, Molecular Pharmacology Program, Sloan Kettering Institutes
Memorial Sloan Kettering Cancer Center
New York, NY
USA

Seigo Kinuya
Professor, Department of Nuclear Medicine
Kanazawa University
Takaramachi, Kanazawa
Japan

Sergey Kanaev
Department of Radiotherapy and Nuclear Medicine
N.N. Petrov Institute of Oncology
St Petersburg
Russia

Seppo Meri
Department of Bacteriology & Immunology
Haartman Institute, University of Helsinki
Helsinki
Finland

Sergey Novikov
Department of Radiotherapy and Nuclear Medicine
N.N. Petrov Institute of Oncology
St Petersburg
Russia

Steven M. Larson
Donna and Benjamin M. Rosen Chair, Molecular Imaging and Therapy Service, Department of Radiology
Memorial Sloan Kettering Cancer Center
New York, NY
USA
/
Laboratory Head, Molecular Pharmacology Program
Sloan Kettering Institute
New York, NY
USA

Sona Balogova
Médecine Nucléaire, Hôpital Tenon
AP-HP Sorbonne Université
Paris
France
/
Department of Nuclear Medicine
Comenius University, Faculty of Medicine; St.Elisabeth Cancer Institute
Bratislava
Slovak Republic

Sonya Sergieva
Department of Nuclear Medicine
Sofia Cancer Center
Sofia
Bulgaria

Sze-Ting Lee
Tumour Targeting Laboratory
Olivia Newton-John Cancer Research Institute
Melbourne
Australia
/
Department of Molecular Imaging and Therapy
Austin Health
Melbourne
Australia
/
School of Cancer Medicine
La Trobe University
Melbourne
Australia
/
Department of Medicine
University of Melbourne
Melbourne
Australia

T.Yu. Kochetova
A. Tsyb Medical Radiological Research Centre - branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation
Obninsk
Russia

Taner Erselcan
Mugla Sitki Kocman University Faculty of Medicine
Mugla
Turkiye
/
Department of Nuclear Medicine
Mugla
Turkiye

Thabo Lengana
Department of Nuclear Medicine
University of Pretoria & Steve Biko Academic Hospital
Pretoria
South Africa

Tuula Penate Medina
Department of Radiology and Neuroradiology
University Medical Center Schleswig-Holstein, Kiel University
Kiel
Germany
/
MOIN CC - Institut für Experimentelle Tumorforschung
Kiel
Germany

Umbreen Hafeez
Tumour Targeting Laboratory
Olivia Newton-John Cancer Research Institute
Melbourne
Australia
/
Department of Medical Oncology
Austin Health
Melbourne
Australia
/
School of Cancer Medicine
La Trobe University
Melbourne
Australia

V.V. Krylov
A. Tsyb Medical Radiological Research Centre - branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation
Obninsk
Russia

Wiktor Szymanski
Stratingh Institute for Chemistry
University of Groningen
Groningen
The Netherlands
/
Department of Radiology, Medical Imaging Center, University of Groningen
University Medical Center Groningen
Groningen
The Netherlands

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