Editors: Surendra Nimesh, Nidhi Gupta, Ramesh Chandra

Nanomaterials: Evolution and Advancement towards Therapeutic Drug Delivery (Part II)

eBook: US $79 Special Offer (PDF + Printed Copy): US $134
Printed Copy: US $95
Library License: US $316
ISBN: 978-1-68108-824-2 (Print)
ISBN: 978-1-68108-823-5 (Online)
Year of Publication: 2021
DOI: 10.2174/97816810882351210101

Introduction

The development of a vector for the delivery of therapeutic drugs in a controlled and targeted fashion is still a major challenge in the treatment of many diseases. The conventional application of drugs may lead to many limitations including poor distribution, limited effectiveness, lack of selectivity and dose dependent toxicity. An efficient drug delivery system can address these problems. Recent nanotechnology advancements in the biomedical field have the potential to meet these challenges in developing drug delivery systems. Nanomaterials are changing the biomedical platform in terms of disease diagnosis, treatment and prevention. Nanomaterials aided drug delivery provides an advantage by enhancing aqueous solubility that leads to improved bioavailability, increased resistance time in the body, decreased side effects by targeting drugs to the specific location, reduced dose dependent toxicity and protection of drugs from early release.

In this two-part book, the contributors have compiled reports of recent studies illustrating the promising nanomaterials that can work as drug carriers which can navigate conventional physiological barriers. A detailed account of several types of nanomaterials including polymeric nanoparticles, liposomes, dendrimers, micelles, carbon nanomaterials, magnetic nanoparticles, solid lipid-based nanoparticles, silica nanomaterials and hydrogels for drug delivery is provided in separate chapters. The contributors also present a discussion on clinical aspects of ongoing research with insights towards future prospects of specific nanotechnologies.

Part II covers the following topics: · Solid lipid nanoparticles and nanostructured lipid carriers · Silica based nanomaterials · Hydrogels · Metallic nanoparticles · Computational and experimental binding interactions of drug and β-cyclodextrin · Clinical milestones in nanotherapeutics · Drug delivery systems based on poly(lactide-co-glycolide) and its copolymers

The book set is an informative resource for scholars who seek updates in nanomedicine with reference to nanomaterials used in drug delivery systems.

Contributors

Editor(s):
Surendra Nimesh
Department of Biotechnology
Central University of Rajasthan
India


Nidhi Gupta
Department of Biotechnology
IIS (Deemed to be University)
India


Ramesh Chandra
Department of Chemistry
University of Delhi
India




Contributor(s):
Ashish Baldi
Department of Pharmaceutical Sciences and Technology
Maharaja Ranjit Singh Punjab Technical University
Bathinda, Punjab
India


Charu Bharti
School of Basic and Applied Sciences
K.R. Mangalam University
Sohna Road, Gurugram, Haryana-122103
India


Chandrabose Selvaraj
Department of Bioinformatics
Alagappa University
Karaikudi-630003
India


Délia Chaves Moreira dos Santos
Department of Pharmaceutics
Faculty of Pharmacy, Federal University of Minas Gerais
Belo Horizonte
Brazil


Faisal A. Almalki
Department of Pharmaceutical Chemistry
Faculty of Pharmacy, Umm Al-Qura University
Makkah Almukkarramah
Saudi Arabia


Gabriel Silva Borges
Department of Pharmaceutics
Faculty of Pharmacy, Federal University of Minas Gerais
BeloHorizonte, MG
Brazil


Guilherme Carneiro
Department of Pharmacy
Faculty of Biological and Health Sciences, Federal University of Jequitinhonha and Mucuri Valleys
Diamantina, MG
Brazil


Jitender Madan
Chandigarh College of Pharmacy
Mohali-140307, Punjab
India


Jyoti Dasharath Magare
C.S.M.S.S Dental College Kanchanwadi
Aurangabad, (M.S.)
India



Kiran Jyoti
Department of Pharmaceutics
Chandigarh College of Pharmacy
Mohali (Punjab)
India


Lucas Antônio Miranda Ferreira
Department of Pharmaceutics
Faculty of Pharmacy, Federal University of Minas Gerais
Belo Horizonte
Brazil


Mariana Silva Oliveira
Department of Pharmaceutics
Faculty of Pharmacy, Federal University of Minas Gerais
Belo Horizonte
Brazil


Muhammed Khalid Saifullah
Department of Pharmaceutical Chemistry
Faculty of Pharmacy, Umm Al-Qura University
Makkah Almukkarramah
Saudi Arabia


Monisha Singhal
Department of Biotechnology
IIS (Deemed to be University)
Jaipur, Rajasthan
India


Neha Bajwa
Department of Pharmaceutical Sciences and Technology
Maharaja Ranjit Singh Punjab Technical University
Bathinda, Punjab
India


Nidhi Gupta
Department of Biotechnology
IIS (Deemed to be University)
Jaipur, Rajasthan
India


Noushad Javed
School of Pharmaceutical Sciences
Apeejay Stya University
Palwal - Sohna Rd, Gurugram Haryana-122103
India


Pradeep Kumar
Nucleic Acids Research Laboratory
CSIR-Institute of Genomics and Integrative Biology
Mall Road -110007, Delhi
India


Preet Amol Singh
Department of Pharmaceutical Sciences and Technology
Maharaja Ranjit Singh Punjab Technical University
Bathinda, Punjab
India


Ramesh Chandra
Dr. B.R. Ambedkar Centre for Biomedical Research
University of Delhi
Delhi
India


Ravi Goyal
Parexel International
Chandigarh
India


Rahul Goel
Nucleic Acids Research Laboratory
CSIR-Institute of Genomics and Integrative Biology
Mall Road -110007, Delhi
India


Reena Singh
Nucleic Acids Research Laboratory
CSIR-Institute of Genomics and Integrative Biology
Mall Road -110007, Delhi
India


Romila Manchanda
School of Basic and Applied Sciences
K.R. Mangalam University
Sohna Road, Gurugram, Haryana-122103
India


Rupinder K. Sodhi
Chandigarh College of Pharmacy
Mohali-140307, Punjab
India


Sabir Alam
School of Basic and Applied Sciences
K.R. Mangalam University
Sohna Road, Gurugram, Haryana-122103
India


Sanjeev Kumar Singh
Department of Bioinformatics
Alagappa University
Karaikudi-630003
India


Seema Gupta
Department of Chemistry
Acharya Narendra Dev College, University of Delhi
New Delhi-110019
India




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