Editor: Atta-ur-Rahman / Khurshid Zaman

Topics in Anti-Cancer Research

Volume 6

eBook: US $99 Special Offer (PDF + Printed Copy): US $168
Printed Copy: US $119
Library License: US $396
ISSN: 2468-5860 (Print)
ISSN: 2213-3585 (Online)
ISBN: 978-1-68108-456-5 (Print)
ISBN: 978-1-68108-455-8 (Online)
Year of Publication: 2017
DOI: 10.2174/97816810845581170601

Introduction

Topics in Anti-Cancer Research covers important advances on both experimental (preclinical) and clinical cancer research in drug development. The book series offers readers an insight into current and future therapeutic approaches for the prevention of different types of cancers, synthesizing new anti-cancer agents, new patented compounds, targets and agents for cancer therapy as well as recent molecular and gene therapy research.

The comprehensive range of themes covered in each volume will be beneficial to clinicians, immunologists, and R&D experts looking for new anti-cancer targets and patents for the treatment of neoplasms, as well as varied approaches for cancer therapy.

The topics covered in the sixth volume of this series include: - The role of microtubules for the cure of various untreated cancers - Novel chemoimmunotherapeutic drug combinations & methods in clinical studies/trials - Targeting polyunsaturated fatty acids (PUFAs) in the treatment of colorectal cancer - Anti-cancer activity of natural and synthetic chalcones and their derivatives - Recent advances in microRNA-based cancer therapeutics - Treatment of heart failure due to inflammation, mitochondria and energy metabolism in cancer cachexia - Regulation/inhibition of human lactate dehydrogenase A for discovering anti-cancer drugs

Indexed in: Chemical Abstracts, Ulrich's Periodicals Directory.

Foreword

The sixth volume of Topics in Anti-Cancer Research presents some exciting contributions in frontier areas of anti-cancer research. These include the role of microtubules for the treatment of various cancers, novel chemoimmunotherapy drug combinations & methods in clinical studies/trial and current studies in targeting polyunsaturated fatty acids (PUFAs) in the treatment of colorectal cancer. Natural and synthetic chalcones and their derivatives that have shown potent anticancer activity against a number of cancer cell lines and murine tumor models are discussed. The discovery of selective small-molecule hLDH-A inhibitors and LDH-based approaches in the progress of anticancer therapy are also presented. Recent advances in microRNA-based cancer therapeutics for the treatment of cancer are presented. The role of inflammation in chemotherapy-induced neuromuscular effects and the side effects and recent relevant patents for beneficial approaches to improve heart failure cases due to inflammation, mitochondria and energy metabolism in cancer cachexia are also covered. It is hoped that the present volume will be found useful by a large number of scientists working in this field.

The editors are thankful to the authors for their excellent contributions and to the reviewers for their in -depth comprehensive comments for the improvement of chapters. We are also grateful to Mr. Mahmood Alam, Mrs. Rafia Rehan and other colleagues for their support and assistance in the finalization of this volume.

Atta-ur-Rahman, FRS
International Center for Chemical and Biological Sciences
University of Karachi
Karachi 75270
Pakistan

Khurshid Zaman
Honorary Editor
Bentham Science Publishers


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