Editor: Norma Rivera

Antiprotozoal Drug Discovery: A Challenge That Remains

eBook: US $49 Special Offer (PDF + Printed Copy): US $126
Printed Copy: US $102
Library License: US $196
ISBN: 978-1-68108-330-8 (Print)
ISBN: 978-1-68108-329-2 (Online)
Year of Publication: 2016
DOI: 10.2174/97816810832921160101

Introduction

Protozoan infections that are endemic in countries with limited economic resources pose a significant public health challenge to affected communities and some of these diseases are categorized as neglected tropical diseases by the World Health Organization. At the moment, there is an urgent need to identify and develop new antiprotozoal drugs. Antiprotozoal Drug Discovery: A Challenge That Remains brings together research from all scientists (including parasitologists, chemists, biologists among others) involved in the field of antiprotozoal experimental pharmacology, drug design and natural product research. The monograph is a compilation of review chapters written by experts on medical parasitology and pharmacology that covers a wide range of topics such as general characteristics of protozoan diseases (malaria, toxoplasmosis, Chagas’ disease, leishmaniasis, trichomoniasis) prophylaxis, treatments, natural products and rational drug design. The contents of this book are useful to medical microbiologists and pharmaceutical scientists seeking to update their knowledge about antiprotozoal drug design.

Foreword

- Pp. i
Filiberto Malagón
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Preface

- Pp. ii
Norma Rivera
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List of Contributors

- Pp. iii-iv (2)
Norma Rivera
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Protozoal Diseases: Importance and Prophylaxis

- Pp. 3-40 (38)
Filiberto Malagón and Elba Carrasco

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Drugs for Parasitic Diseases - Strategies to Solve a Global Problem

- Pp. 41-65 (25)
A. Valeria Pozzoli and Miriam A. Martins Alho

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Crude Extracts and Isolated Compounds with Trypanocidal Activity

- Pp. 66-91 (26)
Paz M. Salazar Schettino, Gloria Rojas, Margarita Cabrera and Martha Bucio

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Malaria, Generalities and New Treatments

- Pp. 92-105 (14)
Luz Eugenia Alcántara-Quintana, Mónica Salas-Rojas and Emmanuelle Alvarado-Alvarez

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Update on Advances in Plant-based Antimalarial Drug Discovery

- Pp. 106-155 (50)
Pius S. Fasinu, Ilias Muhammad and Larry A. Walker

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Metals as an Option for Protozoa Treatment

- Pp. 156-179 (24)
Norma Rivera, Marcela Rojas-Lemus, Gumaro Cano-Gutierrez, Luis F. Montaño and Teresa I. Fortoul

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Subject Index

- Pp. 180-189 (10)
Norma Rivera
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