Editors: Prof. Dr. Atta-ur-Rahman, Prof. Dr. M. Iqbal Choudhary

Anti-Obesity Drug Discovery and Development

Volume 3

eBook: US $79 Special Offer (PDF + Printed Copy): US $158
Printed Copy: US $119
Library License: US $316
ISSN: 2467-9615 (Print)
ISSN: 2210-2698 (Online)
ISBN: 978-1-68108-188-5 (Print)
ISBN: 978-1-68108-187-8 (Online)
Year of Publication: 2017
DOI: 10.2174/97816810818781170301

Introduction

Obesity is a complex health problem, caused by a number of factors such as excessive food intake, lack of physical activity, genetic predisposition, endocrine disorders, medications and psychiatric illnesses. Onset of obesity in both the developing and the developed world has reached epidemic proportions. In response to this, efforts to control and treat obesity have also been vigorously pursued, ranging from raising awareness about lifestyle changes to the discovery and development of safe and effective anti-obesity drugs.

Anti-obesity Drug Discovery and Development is focused on this very important area of healthcare research. The third volume of this series is dedicated to anti-obesity treatments including updates on new therapeutics for obesity, Nesfatin-1 and its therapeutic uses, the role of proteomics in pediatric anti-obesity treatment, the role of oxidative stress in childhood obesity and a review of data on gut microbiota as a treatment option for obesity.

Indexed in: Scopus, Ulrich's Periodicals Directory.

Preface

- Pp. i-ii (2)
Atta-ur Rahman and M. Iqbal Choudhary
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List of Contributors

- Pp. iii
Atta-ur Rahman and M. Iqbal Choudhary
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Current Status of Medical Therapy and New Targets for Anti-Obesity Drug Development

- Pp. 3-64 (62)
Chihiro Okuma, Yukihito Ishii and Takeshi Ohta

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Unravelling Potential Anorexigen Effects of Nesfatin-1: How Homeostatic Mechanisms Help Balance Excess Calories

- Pp. 65-79 (15)
Carmine Finelli

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Proteomics in the Characterization of New Target Therapies in Pediatric Obesity Treatment

- Pp. 80-148 (69)
Gillian E. Walker, Marilisa De Feudis, Marta Roccio, Gianni Bona and Flavia Prodam

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Relationship Between Hormonal Milieu and Oxidative Stress in Childhood Obesity: A Physiopathological Basis for Antioxidant Treatment and Prevention of Cardiovascular Risk

- Pp. 149-203 (55)
Antonio Mancini, Francesco Leo, Chantal Di Segni, Sebastiano Raimondo and Aurora Natalia Rossodivita

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The Role of Gut Microflora in Obesity - Does the Data Provide an Option for Intervention?

- Pp. 204-227 (24)
Parth J. Parekh, Edward C. Oldfield, Amrit Lamba and David A. Johnson

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Subject Index

- Pp. 228-235 (8)
Atta-ur Rahman and M. Iqbal Choudhary
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