Authors: A.K.M. Shamsuddin, Guang-Yu Yang

Inositol & its Phosphates: Basic Science to Practical Applications

eBook: US $49 Special Offer (PDF + Printed Copy): US $143
Printed Copy: US $119
Library License: US $196
ISBN: 978-1-68108-008-6 (Print)
ISBN: 978-1-68108-007-9 (Online)
Year of Publication: 2015

Introduction

Inositol and its phosphates are ubiquitous across most life forms, wherein they play important roles in cellular integrity and functions such as signal transduction, DNA damage repair ion transport and mRNA transport. This reference details the biochemistry and industrial applications of inositol and its phosphate derivatives. Topics covered in this book include the use of inositol and its hexaphosphate (IP6) for numerous health benefits – as antioxidants, as an anti-cancer drug, for the management of atherosclerosis, diabetes, osteoporosis, Alzheimer’s disease, sickle cell anemia, and even in fighting tooth decay. Readers will also learn about Industrial applications of Inositol including preservation of food and wine, nanotechnology, lithium ion battery, fuel cell technology etc. Inositol & its Phosphates: Basic Science to Practical Applications is a valuable reference for any researcher or aspiring biomedical professional seeking to know more about this fascinating metabolite.

Foreword

- Pp. i
Leonard A Cohen
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Preface

- Pp. ii-iii (2)
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Inositol Compounds: Natural Sources and Chemistry

- Pp. 3-15 (13)
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Biosynthesis and Metabolism of Inositol and Inositol Phosphates

- Pp. 16-23 (8)
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Signaling Role of Inositol and its Phosphates

- Pp. 24-49 (26)
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Analysis & Assays of Inositol and Inositol Phosphates

- Pp. 50-56 (7)
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Pharmacokinetics of InsP<sub>6</sub>

- Pp. 57-66 (10)
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Experimental Cancer Prevention by InsP<sub>6</sub> & Inositol

- Pp. 67-82 (16)
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Experimental Cancer Regression by InsP<sub>6</sub> & Inositol

- Pp. 83-106 (24)
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Clinical Studies of Human Cancer Treatment

- Pp. 107-116 (10)
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Radiation Protection by Inositol & its Phosphates

- Pp. 117-127 (11)
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Disorders of Metabolism

- Pp. 128-138 (11)
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Atherosclerosis and Cardiovascular Diseases

- Pp. 139-148 (10)
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Mineralization Disorders

- Pp. 149-163 (15)
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The Roles of Inositol and its Phosphates in Neuropsychiatric Disorders

- Pp. 164-175 (12)
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Sickle Cell Disease and Inositol Phosphates

- Pp. 176-186 (11)
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Polycystic Ovary Syndrome and Therapeutic Potential of Inositol Compounds

- Pp. 187-196 (10)
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Antioxidant Properties & Function of Inositol and Inositol Phosphates

- Pp. 197-215 (19)
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Roles of Inositol & Inositol Phosphates in Immunity, Infection and Inflammation

- Pp. 216-226 (11)
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Mechanisms of Biological Actions of Inositol and InsP<sub>6</sub> I: Cell Survival, Proliferation and Differentiation

- Pp. 227-242 (16)
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Mechanisms of Biological Actions of Inositol and InsP<sub>6</sub> II: DNA Damage Repair

- Pp. 243-251 (9)
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Mechanisms of Biological Actions of Inositol and InsP<sub>6</sub> III: Epigenetics, Telomerase, Angiogenesis

- Pp. 252-260 (9)
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Industrial Applications, Technology & Environmental Sciences

- Pp. 261-274 (14)
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Safety of Inositol and Inositol Phosphates

- Pp. 275-282 (8)
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Glossary

- Pp. 283-291 (9)
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Index

- Pp. 292-294 (3)
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