Editors: Emilio Jirillo, Thea Magrone, Giuseppe Miragliotta

Immune Response to Parasitic Infections: Immunity to Helminths and Novel Therapeutic Approaches

Volume 2

eBook: US $69 Special Offer (PDF + Printed Copy): US $153
Printed Copy: US $119
Library License: US $276
ISSN: 2543-215X (Print)
ISSN: 1879-744X (Online)
ISBN: 978-1-60805-989-8 (Print)
ISBN: 978-1-60805-985-0 (Online)
Year of Publication: 2014
DOI: 10.2174/97816080598501140201


This volume covers research on the interaction of major helminth parasites with the immune system. The main focus of the e-book is the ability of helminths to subvert host immune responses, on the one hand. On the other hand, the immunological armamentarium of the host against invading parasites is described also in the light of new findings on innate and adaptive immunity. These include the discovery of a new category of lymphocytes, innate lymphoid cells, and the role of T helper cels such as Th1, Th2 and Th3 cells, T regulatory (Treg) and Th17 cells in helminth diseases and inflammation. The balance between these two T cell subsets during the various stages of helminth diseases is also discussed. The book concludes with a review of new therapeutic approaches to combat helminth parasites (biotherapy, vaccines and natural products).

Immunity to Helminths and Novel Therapeutic Approaches provides updated information for medical students, clinicians and researchers in the fields of parasitology, applied immunology and novel drug delivery.

Indexed in: EBSCO, Ulrich's Periodicals Directory.


- Pp. i-iii (3)
Claudio M. Mastroianni
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- Pp. iv-vi (3)
Emilio Jirillo, Thea Magrone, Giuseppe Miragliotta
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List of Contributors

- Pp. vii-x (4)
Emilio Jirillo, Thea Magrone, Giuseppe Miragliotta
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Neuroendocrine Control of the Immune Response During Helminth Infections

- Pp. 3-26 (24)
Karen Nava-Castro, Julieta Ivone Castro, Elizabeth Langley, Jorge Morales-Montor
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The Immune Response During Toxocariosis by Toxocara Canis

- Pp. 27-50 (24)
Fernando Alba-Hurtado, Lorena Chávez-Guitrón, Victor Hugo del Río- Araiza, Karen Nava-Castro, Jorge Morales-Montor
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Mechanisms of Immune Modulation by Fasciola Hepatica: The Impact of Innate Immune Cells on the Developing Adaptive Immune Response

- Pp. 51-67 (17)
Sandra M. O’Neill, Sheila Donnelly
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Parasite-Mediated Immune Modulation During the Development of Human Cystic Echinococcosis

- Pp. 69-91 (23)
Elisabetta Profumo, Alessandra Ludovisi, Brigitta Buttari, Maria Angeles Gomez Morales, Rachele Riganò
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The Immunobiology of Urogenital Schistosomiasis

- Pp. 93-124 (32)
Luke F. Pennington, Michael H. Hsieh
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The Translational Immunology of Trichinellosis: From Rodents to Humans

- Pp. 125-161 (37)
Fabrizio Bruschi, Maria Angeles Gómez-Morales
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Anisakis Simplex Infestation and Immune-Mediated Responses

- Pp. 163-173 (11)
Ventura M. Teresa, Buquicchio Rosalba, F. Gatti, F.L. Traetta, G. Iadarola
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Immunomodulation by Parasitic Helminths and its Therapeutic Exploitation

- Pp. 175-212 (38)
Miguel Angel Pineda, William Harnett
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Parasites-Based Immunotherapy to Treat Allergies and Autoimmune Diseases

- Pp. 213-234 (22)
Camila Alexandrina Figueiredo, Valdirene Leão Carneiro, Ryan Santos Costa, Leonardo Nascimento Santos, Raimon Rios, Neuza M Alcantara Neves
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The Impact of Helminths on the Human Microbiota: Therapeutic Correction of Disturbed Gut Microbial Immunity

- Pp. 235-254 (20)
Thea Magrone, Emilio Jirillo, Giuseppe Miragliotta
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Subject Index

- Pp. 255-256 (2)
Emilio Jirillo, Thea Magrone, Giuseppe Miragliotta
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