Editor: Atta-ur-Rahman

Advances in Cancer Drug Targets

Volume 2

eBook: US $89 Special Offer (PDF + Printed Copy): US $163
Printed Copy: US $119
Library License: US $356
ISSN: 2451-8891 (Print)
ISSN: 2213-9915 (Online)
ISBN: 978-1-60805-939-3 (Print)
ISBN: 978-1-60805-938-6 (Online)
Year of Publication: 2014
DOI: 10.2174/97816080593861140201


Advances in Cancer Drug Targets is an e-book series that brings together recent expert reviews published on the subject with a focus on strategies for synthesizing and isolating organic compounds and elucidating the structure and nature of DNA.

The reviews presented in this series are written by experts in pharmaceutical sciences and molecular biology. These reviews have been carefully selected to present development of new approaches to anti-cancer therapy and anti-cancer drug development.

The contents of this book include chapters on heat shock protein 90, spindle assembly checkpoint, ErbB receptors, anti-tumor effects of bisphosphonates, biomarkers for risk assessment and prevention of breast cancer, fibrates action in Daunorubicin chemical reaction and many more.

The reference work serves to give readers a brief yet comprehensive glance at current theory and practice behind employing chemical compounds for tackling tumor suppression, DNA site specific drug targeting and the inhibition of enzymes involved in growth control pathways. This e-book volume will be of special interest to molecular biologists and pharmaceutical scientists.


- Pp. i-iii (3)
Download Free

List of Contributors

- Pp. iv-vi (3)
Download Free

Heat Shock Protein 90 - A Potential Target in the Treatment of Human Acute Myelogenous Leukemia

- Pp. 3-53 (51)
H. Reikvam, R.B. Forthun, A. Brenner, E. Ersvær, K.J. Hatfield, Ø. Bruserud
View Abstract

Spindle Assembly Checkpoint (SAC): More New Targets for Anti-Cancer Drug Therapies

- Pp. 54-79 (26)
Maria Kapanidou, Victor M. Bolanos-Garcia
View Abstract

ErbB Receptors as a Therapeutic Target in Metastatic Cancer Disease

- Pp. 80-126 (47)
Adriano Angelucci
View Abstract

Anti-Tumour Effects of Bisphosphonates - What have we Learned from In Vivo Models?

- Pp. 127-174 (48)
Hannah K. Brown, Ingunn Holen
View Abstract

Bleomycin and its Role in Inducing Apoptosis and Senescence in Alveolar Epithelial Lung Cells - Modulating Effects of Caveolin-1: An Update

- Pp. 175-211 (37)
Michael Kasper, Kathrin Barth
View Abstract

Biomarkers for Risk Assessment and Prevention of Breast Cancer

- Pp. 212-273 (62)
Massimiliano Cazzaniga, Andrea Decensi, Bernardo Bonanni, Alberto Luini, Oreste Gentilini
View Abstract

Modulation of the Myostatin/Follistatin Axis by Deacetylase Inhibitors: Improvement of TNFα-Induced Myotube Atrophy But Not of Experimental Cancer Cachexia

- Pp. 274-295 (22)
Andrea Bonetto, Fabio Penna, Gabriella Bonelli, Francesco M. Baccino, Paola Costelli
View Abstract

Indoleamine 2,3-Dioxygenase, An Emerging Target for Anti- Cancer Therapy

- Pp. 296-327 (32)
Xiangdong Liu, Robert C. Newton, Steven M. Friedman, Peggy A. Scherle
View Abstract

p53 Plays a Key Role in Exporting Bid from the Nucleus to Induce Cell Death in Response to Etoposide Treatment

- Pp. 328-346 (19)
George G. Chen, Gang Song, Baoguang Hu, Liping Liu, Paul B.S. Lai
View Abstract

Fibrates Action in Daunorubicin Chemical Reaction

- Pp. 347-357 (11)
Ganesaratnam K. Balendiran
View Abstract


- Pp. 358-377 (20)
Download Free