Editor: " Atta-ur-Rahman"

Advances in Cancer Drug Targets

Volume 2

Personal Book: US $89 Special Offer (PDF + Printed Copy): US $163
Printed Copy: US $119
Library Book: US $356
ISSN: 2451-8891
eISSN: 2213-9915 (Online)
ISBN: 978-1-60805-939-3
eISBN: 978-1-60805-938-6 (Online)
DOI: 10.2174/97816080593861140201

Introduction

Advances in Cancer Drug Targets is an e-book series that brings together recent expert reviews published on the subject with a focus on strategies for synthesizing and isolating organic compounds and elucidating the structure and nature of DNA.

The reviews presented in this series are written by experts in pharmaceutical sciences and molecular biology. These reviews have been carefully selected to present development of new approaches to anti-cancer therapy and anti-cancer drug development.

The contents of this book include chapters on heat shock protein 90, spindle assembly checkpoint, ErbB receptors, anti-tumor effects of bisphosphonates, biomarkers for risk assessment and prevention of breast cancer, fibrates action in Daunorubicin chemical reaction and many more.

The reference work serves to give readers a brief yet comprehensive glance at current theory and practice behind employing chemical compounds for tackling tumor suppression, DNA site specific drug targeting and the inhibition of enzymes involved in growth control pathways. This e-book volume will be of special interest to molecular biologists and pharmaceutical scientists.

Preface

- Pp. i-iii (3)
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List of Contributors

- Pp. iv-vi (3)
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Heat Shock Protein 90 - A Potential Target in the Treatment of Human Acute Myelogenous Leukemia

- Pp. 3-53 (51)
H. Reikvam, R.B. Forthun, A. Brenner, E. Ersvær, K.J. Hatfield and Ø. Bruserud

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Spindle Assembly Checkpoint (SAC): More New Targets for Anti-Cancer Drug Therapies

- Pp. 54-79 (26)
Maria Kapanidou and Victor M. Bolanos-Garcia

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ErbB Receptors as a Therapeutic Target in Metastatic Cancer Disease

- Pp. 80-126 (47)
Adriano Angelucci

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Anti-Tumour Effects of Bisphosphonates - What have we Learned from In Vivo Models?

- Pp. 127-174 (48)
Hannah K. Brown and Ingunn Holen

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Bleomycin and its Role in Inducing Apoptosis and Senescence in Alveolar Epithelial Lung Cells - Modulating Effects of Caveolin-1: An Update

- Pp. 175-211 (37)
Michael Kasper and Kathrin Barth

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Biomarkers for Risk Assessment and Prevention of Breast Cancer

- Pp. 212-273 (62)
Massimiliano Cazzaniga, Andrea Decensi, Bernardo Bonanni, Alberto Luini and Oreste Gentilini

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Modulation of the Myostatin/Follistatin Axis by Deacetylase Inhibitors: Improvement of TNFα-Induced Myotube Atrophy But Not of Experimental Cancer Cachexia

- Pp. 274-295 (22)
Andrea Bonetto, Fabio Penna, Gabriella Bonelli, Francesco M. Baccino and Paola Costelli

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Indoleamine 2,3-Dioxygenase, An Emerging Target for Anti- Cancer Therapy

- Pp. 296-327 (32)
Xiangdong Liu, Robert C. Newton, Steven M. Friedman and Peggy A. Scherle

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p53 Plays a Key Role in Exporting Bid from the Nucleus to Induce Cell Death in Response to Etoposide Treatment

- Pp. 328-346 (19)
George G. Chen, Gang Song, Baoguang Hu, Liping Liu and Paul B.S. Lai

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Fibrates Action in Daunorubicin Chemical Reaction

- Pp. 347-357 (11)
Ganesaratnam K. Balendiran

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Index

- Pp. 358-377 (20)
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