Editors: Lutfi A. Jaber, Gabrielle J. Halpern

Consanguinity – Its Impact, Consequences and Management

eBook: US $0 Special Offer (PDF + Printed Copy): US $0
Printed Copy: US $96
Library License: US $0
ISBN: 978-1-60805-889-1 (Print)
ISBN: 978-1-60805-888-4 (Online)
Year of Publication: 2014
DOI: 10.2174/97816080588841140101

Introduction

Consanguineous marriages have been practiced for hundreds of years, predominantly by Moslems. Although it is generally accepted among communities that the social advantages outweigh other, the rate of congenital malformations and genetic diseases among the offspring borne of consanguineous marriages is higher and an increase in sterility, rates of abortions, stillbirths and neonatal deaths has been suggested by some researchers. These problems result in a substantial economic burden within the communities involved in the practice. Strategies for reducing the frequency of consanguineous marriages include expansion of educational programs, promotion of genetic testing services, and research to identify the genes responsible for genetic defects. Nowadays, with the migration of large numbers of Moslems towards Western countries, consanguinity is becoming a practical issue in places where it was barely known, previously. This eBook serves as a guide for health care workers and counselors of the phenomenon and its associated problems. This eBook begins with an introduction of the topic from a social, legal and biological perspective. It then progresses to research about associated genetic disorders, reproductive and social awareness issues through the proceeding chapters. The eBook concludes with 2 chapters exploring strategies to counter the effects of consanguinity within the general population.

Editor’s Biography

- Pp. i
Lutfi A. Jaber and Gabrielle J. Halpern
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Foreword

- Pp. ii
Joel Zlotogora
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Preface

- Pp. iii-vi (4)
Lutfi A. Jaber and Gabrielle J. Halpern
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List of Contributors

- Pp. vii
Lutfi A. Jaber and Gabrielle J. Halpern
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Definition, Background, History, and Legal, Religious and Biological Aspects

- Pp. 3-30 (28)
Lutfi Jaber and Gabrielle J. Halpern
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Prevalence and Epidemiology

- Pp. 31-49 (19)
Lutfi Jaber and Gabrielle J. Halpern
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General Health Topics Associated with Consanguinity; Genetic Disorders and Congenital Malformations; Benefits

- Pp. 50-74 (25)
Lina Basel-Vanagaite, Gabrielle J. Halpern and Lutfi Jaber
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Consanguinity and Susceptibility to Common Diseases

- Pp. 75-93 (19)
Hagit N. Baris, Wen-Hann Tan and Gabrielle J. Halpern
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Consanguinity and Fertility and Reproductive Issues

- Pp. 94-116 (23)
Lutfi Jaber and Gabrielle J. Halpern
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Awareness and Knowledge about Consanguinity-Related Problems among Members of Communities Where the Custom is Prevalent

- Pp. 117-135 (19)
Gabrielle J. Halpern and Lutfi Jaber
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Future Strategies 1 – Educational and Counseling Programs

- Pp. 136-157 (22)
Gabrielle J. Halpern and Lutfi Jaber
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Future Strategies 2 – Genetic Perspectives – Counseling, Screening, Testing, Research, and Intervention

- Pp. 158-176 (19)
Gabrielle J. Halpern, Lina Basel-Vanagaite and Lutfi Jaber
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Index

- Pp. 177-179 (3)
Lutfi A. Jaber and Gabrielle J. Halpern
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