Editor: "John W. Cherwonogrodzky"

Ricin Toxin

Personal Book: US $0 Special Offer (PDF + Printed Copy): US $118
Printed Copy: US $119
Library Book: US $0
ISBN: 978-1-60805-879-2
eISBN: 978-1-60805-878-5 (Online)
DOI: 10.2174/97816080587851140101

Introduction

`Ricin Toxin’ brings together a collection of in depth and cutting edge reviews that focus on the current understanding of ricin toxins. This e-book provides a historical background, innovations in detection, identification and medical countermeasures against this biothreat, and the toxin’s previous use as an anti-cancer agent.

This e-book answers various important questions such as detection of ricin in food or soil, making of humanized antibody against the toxin, novel approaches for the creation of a safe vaccine to protect first responders, exploitation of toxin`s ability to bind and penetrate cells for medical benefits, aftereffects of administering antibody against ricin to a first responder and their exposure to the toxin, neutralization of different ricin from different castor plant cultivars. Aside from learning key concepts that may be overlooked while scanning literature, the reader will benefit from gems of information scattered throughout the book.

The book comprises of five different parts. The first part covers the background of ricin from pharaohs to bioterrorists and beyond.

The second part covers the discovery of recent technologies which are very helpful for the detection of ricin in different matrices, followed by the detection of ricin in the sorption of soils, minerals,textiles, and food; soil inflatration and dust transport. The third part covers the ricin and castor plant cultivars. It also discusses the antibody therapies such as Polyclonal and monoclonal antibodies and the extraction of ricin toxin from several cultivars of the Castor Plant (Ricinus communis).

The fourth part of this e-book discusses different medical countermeasures which are very effective in enhancing the progress in the development of vaccines against ricin intoxication. This part also describes different methods employed for the improvement of anti-ricin antibodies.

The last part of this book describes the replacement and different applications of the toxin. All chapters are written by paramount experts in ricin research.

`Ricin Toxin’ is an essential reading to all medical students, biochemists and professionals involved in the field of toxicology.

Indexed in: Book Citation Index, Science Edition, BIOSIS Previews, EBSCO.

Contributors

Editor(s):
John W. Cherwonogrodzky
(DRDC), Suffield Research Centre
Ralston, Alberta
California
Canada




Contributor(s):
Bernard Degryse
School of Health and Human Performance
Faculty of Science and Health, Dublin City University
Dublin 9
Ireland


Calvin L. Trostle
AgriLife Extension, Department of Soil and Crop Sciences
Texas A&M University, College Station
Texas
USA


Charles Chen Hu
Bio Threat Defence Section, Defence Research and Development Canada (DRDC)
Suffield Research Centre, Canadian Forces Base Suffield
Ralston
Alberta
Canada


Johnson Clorinda
Research Institute for Children
Children’s Hospital and LSU Health Sciences Center
New Orleans
Louisiana
USA


Braun Curtis
Systems management Consulting
Surrey
British Columbia
Canada


Chong Damien
Defence Science and Technology Organisation (DSTO)
Fishermans Bend (City of Melbourne)
Victoria
Australia


Chau Damon
Bio Threat Defence Section, Defence Research and Development Canada (DRDC)
Suffield Research Centre, Canadian Forces Base Suffield
Ralston
Alberta
Canada


Dick L. Auld
Texas AgriLife Research, Plant and Soil Science
Texas Tech University
Lubbock
Texas
USA


Dominik Stoll
BC Cancer Agency’s Genome Sciences Centre
Vancouver
British Columbia
Canada


Stewart Donald IH
Professor, Department of Neurosciences and the Center on Aging
PlantForm Corporation
Toronto
Ontario
Canada


Erik J. Wiersma
Ministry of Health and Long-term Care
Ontario Government Pharmaceutical and Medical Supply
Charleston, Concord
Ontario
Canada


Grace Maresh
Research Institute for Children
Children’s Hospital and LSU Health Sciences Center
New Orleans
Louisiana
USA


John W. Cherwonogrodzky
Bio Threat Defence Section, Defence Research and Development Canada (DRDC)
Suffield Research Centre, Canadian Forces Base Suffield
Ralston
Alberta
Canada


Junfei Yin
Bio Threat Defence Section, Defence Research and Development Canada (DRDC)
Suffield Research Centre, Canadian Forces Base Suffield
Ralston
Alberta
Canada


Kejing Song
Research Institute for Children
Children’s Hospital and LSU Health Sciences Center
New Orleans
Louisiana
USA


Laurel M. Negrych
Bio Threat Defence Section, Defence Research and Development Canada (DRDC)
Suffield Research Centre, Canadian Forces Base Suffield
Ralston
Alberta
Canada


Leonard A. Smith
Medical Countermeasures Technology, Office of Chief Scientist
United States Army Medical Research Institute of Infectious Diseases (USAMRIID)
Fort Detrick
Maryland
USA


Maddalena De Virgilio
National Council of Research
Institute of Biosciences and Bioresources (IBBR)
Bari
Italy


Martha L. Hale
Integrated Toxicology Division
United States Army Medical Research Institute of Infectious Diseases (USAMRIID)
Fort Detrick
Maryland
USA


Michael Fung
Suffield Research Centre
Canadian Forces Base Suffield
Ralston
Alberta
Canada


Rayanne Hilsen
Risk and Hazards Assessment Group, Defence Research and Development Canada (DRDC)
Suffield Research Centre, Canadian Forces Base Suffield
Ralston
Alberta
Canada


Richard E. Zartman
Department of Plant and Soil Science, College of Agricultural Sciences and Natural Resources
Texas Tech University
Lubbock
Texas
USA


Robert W. Duncan
Department of Plant Science
University of Manitoba
Winnipeg
Manitoba
Canada


Scott J. Jager
Bio Threat Defence Section, Defence Research and Development Canada (DRDC)
Suffield Research Centre, Canadian Forces Base Suffield
Ralston
Alberta
Canada


Seth H. Pincus
Research Institute for Children
Children’s Hospital and LSU Health Sciences Center
New Orleans
Louisiana
USA


Thor Borgford
Faculty of Science and Technology
Douglas College
British Columbia
New Westminster
Canada


Travis D. Miller
AgriLife Extension, Department of Soil and Crop Sciences
Texas A&M University
College Station
Texas
USA


Vadim Tsvetnitsky
PATH
Washington
D.C.
USA


Veronica Restelli
CMPT, Department of Pathology and Laboratory Medicine
University of British Columbia
British Columbia
Canada


Virginia I. Roxas-Duncan
Biosurety Division
United States Army Medical Research Institute of Infectious Diseases (USAMRIID)
Fort Detrick
Maryland
USA


Wei-Gang Hu
Bio Threat Defence Section, Defence Research and Development Canada (DRDC)
Suffield Research Centre, Canadian Forces Base Suffield
Ralston
Alberta
Canada


William F. Jaynes
Department of Plant and Soil Science
College of Agricultural Sciences and Natural Resources, Texas Tech University
Lubbock
Texas
USA


Xiaohua He
Foodborne Contaminants Research Unit, Western Regional Research Center
Agricultural Research Services, U.S. Department of Agriculture (USDA)
Albany
California
USA




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