Editors: Atta-ur-Rahman, Muhammad Iqbal Choudhary, George Perry

Recent Advances in Medicinal Chemistry

Volume 1

eBook: US $199 Special Offer (PDF + Printed Copy): US $304
Printed Copy: US $205
Library License: US $796
ISSN: 2215-0722 (Print)
ISBN: 978-1-60805-797-9 (Print)
ISBN: 978-1-60805-796-2 (Online)
Year of Publication: 2014
DOI: 10.2174/97816080579621140101

Introduction

Recent advances in Medicinal Chemistry is a book series focused on leading-edge research on developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. The series presents highly cited contributions first published in the impact factor journal Mini-Reviews in Medicinal Chemistry. Contributors to this volume have updated their work with new experimental data and references following their initial research. Each volume highlights a number of important topics in current research in medicinal chemistry.

Selected chapters in this volume include:

  • - Characterization of Inorganic Nanomaterials as Therapeutic Vehicles
  • - HPLC and its Essential Role in the Analysis of Tricyclic Antidepressants in Biological Samples
  • - Tannins and Their Influence on Health

… And much more.

Foreword

- Pp. i-ii (2)
Daniel C. Hoessli
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Preface

- Pp. iii
George Perry
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List of Contributors

- Pp. iv-xi (8)
Atta-ur-Rahman, Muhammad Iqbal Choudhary and George Perry
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New Functions of Old Drugs: Aureolic Acid Group of Anti- Cancer Antibiotics and Non-Steroidal Anti-Inflammatory Drugs

- Pp. 3-55 (53)
Hirak Chakraborty, Pukhrambam Grihanjali Devi, Munna Sarkar and Dipak Dasgupta

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Updated Report on a Novel Mercaptopyruvate Sulfurtransferase Thioredoxin-Dependent Redox-Sensing Molecular Switch: A Mechanism for the Maintenance of Cellular Redox Equilibrium

- Pp. 56-72 (17)
Noriyuki Nagahara

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Characterization of Inorganic Nanomaterials as Therapeutic Vehicles

- Pp. 73-98 (26)
Tatsuya Murakami, Masako Yudasaka, Sumio Iijima and Kunihiro Tsuchida

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Aromatase Inhibitors: A New Reality for the Adjuvant Endocrine Treatment of Early-Stage Breast Cancer in Postmenopausal Women

- Pp. 99-130 (32)
Colozza Mariantonietta, Minenza Elisa, Nunzi Martina, Sabatini Silvia, Dinh Phuong, Califano Raffaele and De Azambuja Evandro

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Bacterial FabH: Towards the Discovery of New Broad-Spectrum Antibiotics

- Pp. 131-158 (28)
Yunierkis Pérez-Castillo, Matheus Froeyen, Ann Nowé and Miguel Ángel Cabrera-Pérez

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Tannins and their Influence on Health

- Pp. 159-208 (50)
Kateřina Macáková, Vít Kolečkář, Lucie Cahlíková, Jakub Chlebek, Anna Hošťálková, Kamil Kuča, Daniel Jun and Lubomír Opletal

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Rho-GTPases and Statins: A Potential Target and a Potential Therapeutic Tool Against Tumors?

- Pp. 209-245 (37)
Ivana Campia, Sophie Doublier, Elisabetta Aldieri, Amalia Bosia, Dario Ghigo and Chiara Riganti

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Carotenoids that are Involved in Prostate Cancer Risk

- Pp. 246-271 (26)
Charles Y.F. Young, K.V. Donkena, H.-Q. Yuan, M.-L. He and J.-Y. Zhang

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Preclinical Studies of Saponins for Tumor Therapy

- Pp. 272-302 (31)
Christopher Bachran, Silke Bachran, Mark Sutherland, Diana Bachran and Hendrik Fuchs

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Pharmacological Neuroprotection for Acute Spinal Cord Injury

- Pp. 303-331 (29)
Humberto Mestre, Ricardo Balanza and Antonio Ibarra

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HPLC and its Essential Role in the Analysis of Tricyclic Antidepressants in Biological Samples

- Pp. 332-380 (49)
V.F. Samanidou, M.K. Nika and I.N. Papadoyannis

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Gene Expression Profiles in Breast Cancer to Identify Estrogen Receptor Target Genes

- Pp. 381-403 (23)
Maria Aparecida Nagai and Brentani M.M.

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Trans-Plasma Membrane Electron Transport in Human Blood Platelets: An Update

- Pp. 404-432 (29)
Luciana Avigliano, I. Savini, M. V. Catani and D. Del Principe

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Role of Intermediate States in Protein Folding and Misfolding

- Pp. 433-455 (23)
Roberto Santucci, Fabio Polticelli, Federica Sinibaldi and Laura Fiorucci

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Index

- Pp. 456-469 (14)
Atta-ur-Rahman, Muhammad Iqbal Choudhary and George Perry
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