Author: Marcus V.N. de Souza

Tuberculosis Treatment: The Search For New Drugs

eBook: US $79 Special Offer (PDF + Printed Copy): US $158
Printed Copy: US $119
Library License: US $316
ISBN: 978-1-60805-789-4 (Print)
ISBN: 978-1-60805-788-7 (Online)
Year of Publication: 2013
DOI: 10.2174/97816080578871130101

Introduction

Despite the high impact on human health caused by Tuberculosis (TB) infections worldwide, nearly 45 years have passed since a novel drug was introduced for its treatment. As MDR-TB and XDR-TB cases rise globally new strategies and drugs are desperately needed to address this problem. Tuberculosis Treatment: The Search For New Drugs covers a wide range of topics about TB drug discovery. The e-book begins with historical information about Tuberculosis discovery and treatment and explores modern treatment strategies, formulations (synthetic and natural) and class of compounds. The extraction of important drugs from various sources is also covered in separate chapters along with information about promising drugs undergoing clinical testing. The e-book is a useful reference for readers interested in learning about the array of pharmaceuticals discovered and used to combat Mycobacterium tuberculosis infections.

Indexed in: Book Citation Index, Science Edition, BIOSIS Previews, EBSCO.

Foreword

- Pp. i
J.L. Wardell
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Preface

- Pp. ii-iv (3)
Marcus V.N. de Souza
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Abbreviations

- Pp. v-ix (5)
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Important Historical Facts of Tuberculosis Treatment and Drug Development

- Pp. 3-37 (35)
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Promising Drug Candidates in Advanced Clinical Trials

- Pp. 38-74 (37)
Marcus V.N. de Souza

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Known Drugs Against Different Targets or Diseases Evaluated Against Tuberculosis

- Pp. 75-100 (26)
Marcus V.N. de Souza

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Synthetic Anti-TB Compounds

- Pp. 101-137 (37)
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Compounds in Clinical Studies Based on Natural Products

- Pp. 138-157 (20)
Marcus V.N. de Souza

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Anti-TB Evaluation of Natural Products From Plants

- Pp. 158-179 (22)
Marcus V.N. de Souza

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Anti-TB Evaluation of Natural Products From Fungus

- Pp. 180-195 (16)
Marcus V.N. de Souza

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Anti-TB Evaluation of Marine Natural Products

- Pp. 196-216 (21)
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Index

- Pp. 217-225 (9)
Marcus V.N. de Souza
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