Editor: Kenneth Wayne Berendzen

The Analysis of Regulatory DNA: Current Developments, Knowledge and Applications Uncovering Gene Regulation

eBook: US $69 Special Offer (PDF + Printed Copy): US $147
Printed Copy: US $113
Library License: US $276
ISBN: 978-1-60805-711-5 (Print)
ISBN: 978-1-60805-492-3 (Online)
Year of Publication: 2013
DOI: 10.2174/97816080549231130101

Introduction

A major goal of integrative research is understanding regulatory networks to such an extent as to allow researchers to model developmental and stress responses. Regulatory networks of living systems include complex and vast interactions between proteins, metabolites, RNA, various signaling molecules and DNA. One aspect of systems biology is understanding the dynamics of protein-DNA interactions affecting gene expression that are caused by transcription factors (TFs) and chromatin remodeling factors. This e-book provides a resource for summarizing current knowledge eukaryotic transcription and explores cis-elements and methods for their analysis, prediction and discovery. The book also presents an overview of exploring gene regulatory networks, chromatin, and miRNAs. Information about state-of-the-art techniques for the determination of TF - cis -element interactions in vivo and in silico give cutting edge insights on how genomic-scale research is being approached. The Analysis of Regulatory DNA provides readers with both the necessary background knowledge and provocative, up-to-date insights aimed at sparking new and vibrant experimental designs for understanding and predicting cis-elements in the eukaryotic genome.

Contributors

Editor(s):
Kenneth Wayne Berendzen
Center for Plant Molecular Biology (ZMBP)
University of Tübingen
Tübingen
Germany




Co-Editor(s):
Joachim Kilian
Center for Plant Molecular Biology (ZMBP)
University of Tübingen
Tübingen
Germany


Dierk Wanke
Center for Plant Molecular Biology (ZMBP)
University of Tübingen
Tübingen
Germany




Contributor(s):
Lúcia E. Alvares
Department of Histology and Embryology
State University of Campinas –UNICAMP
Campinas (São Paulo)
Brazil


Kenneth W. Berendzen
Central Facility Core Manager of Plant Transformation and Flow Cytometry
Center for Plant Molecular Biology (ZMBP)
University of Tübingen
Tübingen
Germany


Anthony Bolger
Research Doctoral Candidate, RWTH Aachen University, Aachen
Germany Luise H. Brand Center for Plant Molecular Biology (ZMBP)
University of Tübingen
Tübingen
Germany


Hozana A. Castillo
Brazilian National Laboratory for Biosciences
Brazilian Association for Synchrotron Light Technology
Campinas (São Paulo)
Brazil


Susanne Dietrich
Institute of Biomedical and Biomolecular Sciences
School of Biological Sciences
University of Portsmouth
Portsmouth
U. K.


Nina M. Fischer
Applied Bioinformatics
Centre for Bioinformatics (ZBIT)
University of Tübingen
Tübingen
Germany


Carla V. C. Grade
Department of Histology and Embryology
State University of Campinas –UNICAMP
Campinas (São Paulo)
Brazil


Nicolas Jonckheere
Team 5 "Mucins, epithelial differentiation and carcinogenesis" laboratory
Inserm UMR837, Jean-Pierre Aubert Research Center
Lille
France


Joachim Kilian
Center for Plant Molecular Biology (ZMBP)
University of Tübingen
Tübingen
Germany


Oliver Kohlbacher
Applied Bioinformatics
Centre for Bioinformatics (ZBIT)
University of Tübingen
Tübingen
Germany


Üner Kolukisaoglu
Center for Plant Molecular Biology (ZMBP)
University of Tübingen
Tübingen
Germany


Mônica S. Salerno
Growth and Lactation
Ruakura Research Centre
AgResearch
Hamilton
New Zealand


Santosh B. Satbhai
Gregor Mendel Institute of Molecular Plant Biology
Vienna
Austria


Isabelle Van Seuningen
Team 5 "Mucins, epithelial differentiation and carcinogenesis" laboratory
Inserm UMR837, Jean-Pierre Aubert Research Center
Lille
France


Frank R. Shubert
Institute of Biomedical and Biomolecular Sciences
School of Biological Sciences
University of Portsmouth
Portsmouth
U. K.


Dóra Szakonyi
Department of Plant Systems Biology
Ghent University
Ghent
Belgium


Björn Usadel
Professor RWTH Aachen University
Co-Director at the Forschungszentrum Jülich
RWTH Aachen University, Forschungszentrum Jülich
Aachen, Germany
Jülich
Germany


Audrey Vincent
Team 5 "Mucins, epithelial differentiation and carcinogenesis" laboratory
Jean-Pierre Aubert Research Center
Inserm UMR837
Lille
France


Dirk Walther
Central Infrastructure Group Bioinformatics
Max Planck Institute for Molecular Plant Physiology
Golm
Germany


Dierk Wanke
Center for Plant Molecular Biology (ZMBP)
University of Tübingen
Tübingen
Germany


José Xavier-Neto
Brazilian National Laboratory for Biosciences
Brazilian Association for Synchrotron Light Technology
Campinas(São Paulo)
Brazil


Jianzhen Xu
College of Bioengineering
Henan University of Technology
Zhengzhou
P.R.China


Shijun Xu
College of Bioengineering
Henan University of Technology
Zhengzhou
P.R.China




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