Frontiers in Drug Design and Discovery

Volume 4

eBook: US $44 Special Offer (PDF + Printed Copy): US $237
Printed Copy: US $215
Library License: US $176
ISSN: 1574-0889 (Print)
ISSN: 2212-1064 (Online)
ISBN: 978-1-60805-526-5 (Print)
ISBN: 978-1-60805-202-8 (Online)
Year of Publication: 2009
DOI: 10.2174/97816080520281090401

Introduction

Frontiers in Drug Design and Discovery is a book series devoted to publishing the latest and the most important advances in drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. The book series should prove to be of interest to all the pharmaceutical scientists involved in research in drug design and discovery. Each volume is devoted to the major advances in drug design and discovery.

The book series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

The book series is available in print, online and CD editions.

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EMBASE, Scopus, Genamics JournalSeek

Indexed in: Scopus, EMBASE, EBSCO, Ulrich's Periodicals Directory.

Editorial: Biopharmaceutical & Pharmacokinetic Considerations in Drug Design & Discovery

- Pp. i-iii (3)
Atta-ur-Rahman, Gary W. Caldwell, M. Iqbal Choudhary and Zhengyin Yan
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Present and Future Mass Spectrometry-Based Approaches for Exploratory Drug Metabolism and Pharmacokinetic Studies

- Pp. 1-22 (22)
Yunsheng Hsieh

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Glutathione Transferases in Drug Discovery and Development: Towards Safer and Efficacious Drugs

- Pp. 23-42 (20)
Katholiki Skopelitou, Dimitris Platis, Irene Axarli and Nikolaos E. Labrou

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New Sampling Techniques for Pharmacokinetic- Pharmacodynamic Modeling

- Pp. 43-80 (38)
Christian Höcht, Marcos Mayer, Javier A.W. Opezzo, Guillermo F. Bramuglia and Carlos A. Taira

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Role of Inflammatory Biomarkers in Establishing PK/PD Relationships and Target Organ Toxicity

- Pp. 81-96 (16)
Sivaram Pillarisetti and Ish Khanna

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Important Drug Interactions for Clinical Oncologists

- Pp. 97-121 (25)
Hiroshi Ishiguro, Ikuko Yano and Masakazu Toi

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Pharmacogenomic Considerations in Breast Cancer Management

- Pp. 122-134 (13)
Hiroshi Ishiguro, Ikuko Yano and Masakazu Toi
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More Than Skin Deep: The Human Skin Tissue Equivalent as an Advanced Drug Discovery Tool

- Pp. 135-161 (27)
Alexandra S. Bause, Sarah D. Lamore and Georg T. Wondrak

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Across Skin Barrier: Known Methods, New Performances

- Pp. 162-188 (27)
Krzysztof Cal

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The Tape Stripping Method as a Valuable Tool for Evaluating Topical Applied Compounds

- Pp. 189-227 (39)
J.J. Escobar-Chávez, L.M. Melgoza-Contreras, M. López-Cervantes, D. Quintanar-Guerrero and A. Ganem-Quintanar

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Methylphenidate Extended-Release Capsules: A New Formulation for Attention-Deficit Hyperactivity Disorder

- Pp. 228-246 (19)
Pilar García-García, Francisco López-Muñoz, Juan D. Molina, Roland Fischer and Cecilio Alamo

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Osmotic-Controlled Release Oral Delivery System (OROS® Technology) in Chronic Pain Management

- Pp. 247-272 (26)
Flaminia Coluzzi and Consalvo Mattia

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Drug Delivery Systems Prepared by Membrane Emulsification

- Pp. 273-290 (18)
C. Charcosset and H. Fessi

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In Silico ADME Approaches

- Pp. 291-332 (42)
Nuria E. Campillo and Juan A. Páez

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Advances in ADMET Predictions and Modeling: Rapid Drug Discovery Efforts in 21st Centuries

- Pp. 333-350 (18)
Mahmud Tareq Hassan Khan

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Computational Intelligence Methods for ADMET Prediction

- Pp. 351-377 (27)
David Hecht and Gary B. Fogel
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Data Modeling and Chemical Interpretation of ADME Properties Using Regression and Rule Mining Techniques

- Pp. 378-428 (51)
Kiyoshi Hasegawa and Kimito Funatsu

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A Review on Virtual Reality and Haptics Approaches in Drug Design and Discovery

- Pp. 429-453 (25)
Susana K. Lai-Yuen

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Contributors

- Pp. 454-457 (4)
Atta-ur-Rahman
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