Editor: "Ashim K. Mitra"

Treatise on Ocular Drug Delivery

Personal Book: US $99 Special Offer (PDF + Printed Copy): US $168
Printed Copy: US $119
Library Book: US $396
ISBN: 978-1-60805-347-6
eISBN: 978-1-60805-175-5 (Online)
DOI: 10.2174/97816080517551130101

Introduction

A multidisciplinary approach is increasingly being adapted by the Pharmaceutical industry to tackle several challenges in developing efficacious treatment solutions. The field of Ophthalmology is no less different. Treatise on Ocular Drug Delivery is a unique collection of information put together by various experts in the field. One of the major goals behind this volume is to link clinical information with the current strategies employed in ocular drug delivery. This monograph covers a range of topics on ocular pharmacology. Chapters in the e-book cover several aspects of drug delivery research such as the biochemical background of specific eye diseases, challenges for ocular drug delivery, the role of influx and efflux transporters, novel drug delivery systems, pharmacokinetics, regulatory aspects, and patenting opportunities for researchers. This E-Book would serve as a suitable reference for pharmacy graduates, medical students, professional scientists and ophthalmic clinicians in academic and industrial laboratories.

Preface

Over the last three decades, considerable attention has been paid to the field of ocular drug delivery due to challenges encountered in delivery of ocular drugs. The global market for ocular therapeutics in 2008 was approximately $ 12.5 billion, which has been rising at a constant rate of 9% every year. This result was achieved from significant research efforts provided by ocular drug delivery scientists and researchers across the globe. Despite the complex anatomy and physiology of the eye, drug delivery to this globe has been widely explored with many novel drug delivery systems, devices and newly developed technologies such as nanotechnology, iontophoresis and phonophoresis. The primary objective of this eBook is to provide a comprehensive understanding of ocular barriers and highlight current progress in the field of ocular drug delivery.

In this eBook, recent advances and developments in ocular drug delivery systems have been specifically addressed. Ocular anatomy and physiology along with a distinctive comparison between conventional and novel routes for drug delivery have been described. A detailed review on the development of liposomes, nanoparticles, implants and nanomicelles which has revolutionized drug delivery to both anterior and posterior segment of the eye has also been discussed. Novel strategies such as ocular iontophoresis, phonophoresis and transporter targeted prodrug delivery which are being currently investigated for improving ocular drug delivery have also been provided. This eBook will definitely serve as an excellent reference to all future ocular researchers and scientists striving to improve drug delivery to the eye.

Ashim K. Mitra
Division of Pharmaceutical Sciences,
University of Missouri-Kansas City,
USA

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