Editor: Michel Goldberg

Series Title: Frontiers between Science and Clinic in Odontology

Amelogenins: Multifaceted Proteins for Dental and Bone Formation and Repair

Volume 1

eBook: US $99 Special Offer (PDF + Printed Copy): US $168
Printed Copy: US $119
Library License: US $396
ISSN: 2589-3076 (Print)
ISSN: 2210-2841 (Online)
ISBN: 978-1-60805-606-4 (Print)
ISBN: 978-1-60805-171-7 (Online)
Year of Publication: 2010
DOI: 10.2174/97816080517171100101

Introduction

This volume is the 1st in a series of Ebooks that bridges the gap between advances in science and clinical practice in odontology. Recent advances in biology, materials science and tissue engineering are increasingly viewed as being of enormous clinical potential. Stem cell research has opened up the possibility of reconstructing teeth from the association of epithelial and mesanchymal embryonic or adult cells, as an exciting alternative to metal implants. This Ebook will examine the multifunctional nature of a group of proteins known as the amelogenins. Latest studies indicate that this protein regulates the initiation and growth of hydroxyapatite crystals during the mineralization of enamel. In addition, amelogenins organize enamel rods during tooth development, and also aid in the development of cementum by directing cells that form the cementum to the root surface of the teeth. The aim of this book is to serve as a bridge between basic biology and biomaterial sciences, and to inform clinicians about the implications of recent advances within these fields for clinical practice.

Indexed in: Chemical Abstracts, EBSCO, Ulrich's Periodicals Directory.

Contributors

Editor(s):
Michel Goldberg
Professor Emeritus, University of Paris Vth (University René Descartes)
France




Contributor(s):
Tabitha A. Abrazinski
Laboratory Assistant
BS Forsyth Institute



Jerry Antone
Laboratory Assistant
BS Forsyth Institute



John D. Bartlett
Senior Member of Staff, PhD Forsyth Institute



Elia Beniash
Associate Professor, University of Pittsburgh School of Dental Medicine
589 Salk Hall, 3501 Terrace Street Pittsburgh
Pennsylvania, 15261
USA


Anat Blumenfeld Ph.D.
Hebrew University
Jerusalem
Israel


Dieter Bosshardt
Department of Periodontology
University of Bern
Bern
Switzerland


Michel Brecx
Department of Conservative Dentistry and Periodontology
University of Tübingen
Tübingen
Germany


Steven J. Brookes
Senior Lecturer, University of Leeds



Dan Deutsch
Professor, Hebrew University
Jerusalem
Israel


Yong-Hee P. Chun
Assistant Professor, Department of Periodontics
University of Texas Health Science Center at San Antonio
San Antonio
Texas, 78229-3900
USA


Pamela DenBesten
Professor, University of California
San Francisco
CA, 94110
USA


Sasha Dimitrova-Nakov
Assistant Professor, Oral Biology, PhD student
Paris Descartes, U747
France


Carolyn W. Gibson
Professor, Department of Anatomy and Cell Biology
University of Pennsylvania School of Dental Medicine
240 S. 40th Street
Philadelphia
PA, 19104
USA


Michel Goldberg
Professor emeritus, University Paris Descartes
Biomedicale St Pères
France


Yael Gruenbaum-Cohen D.M.D.
Hebrew University
Jerusalem
Israel


Yassine Harichane
Assistant Professor, Oral Biology, PhD student
Paris Descartes, U747
France


Naoto Haruyama
Professor, Global Center of Excellence Program
International Research Center for Molecular Science in Tooth and Bone Diseases
Maxillofacial Orthodontics, Department of Maxillofacial Reconstruction and Function
Division of Maxillofacial/Neck Reconstruction, Graduate School
Tokyo Medical and Dental University
Tokyo
Japan


Junko Hatakeyama
Global Center of Excellence Program
International Research Center for Molecular Science in Tooth and Bone Diseases
Tokyo Medical and Dental University
Tokyo, U747
Japan


Yuji Hatakeyama
Global Center of Excellence Program
International Research Center for Molecular Science in Tooth and Bone Diseases
Tokyo Medical and Dental University
Tokyo
Japan


Amir Haze M.D.
Hebrew University
Jerusalem
Israel


Jan C.-C. Hu
Professor, Dept. of Biologic and Materials Sciences
University of Michigan School of Dentistry
Ann Arbor
MI, 48108
USA


Z Huang
Research Associate, Center for Craniofacial Molecular Biology
The University of Southern California
2250 Alcazar Street Clinical Science Annex 107
Los Angeles
CA, 90033
USA


Stanca Iacob
Instructor, Department of Biochemistry
Rush University Medical Center 1735 W. Harrison
Street, 5th Fl-CRB
Chicago
IL, 60612
USA


Odile Kellermann
Professor, University Paris Descartes
France


Ashok B. Kulkarni
Functional Genomics Section, Laboratory of Cell and Developmental Biology
Department of Health and Human Services, National Institute of Dental and Craniofacial Research
National Institutes of Health
Bethesda
MD
USA


Rodrigo S. Lacruz
Research Associate, Center for Craniofacial Molecular Biology
The University of Southern California
2250 Alcazar Street, Clinical Science Annex 107
Los Angeles
CA, 90033
USA


Rajamani Lakshminarayanan
Senior Research Scientist
Singapore Eye Research Institute
Singapore


Grace F. Lopez
Laboratory Assistant, BA Forsyth Institute



Wu Li
Associate Professor, University of California
San Francisco
CA
USA


S. Peter Lyngstadaas
Professor, University of Oslo



Mary Mac Dougall
Associate Dean for Research and Director
Institute of Oral Health Research, Birmingham
Alabama
CA
USA


Henry C. Margolis
Senior Member of the Staff, The Forsyth Institute
140 The Fenway, Boston
Massachusetts , 02115
USA


Antonio Nanci
Professor, Laboratory for the Study of Calcified Tissues and Biomaterials
Faculty of Dentistry, Université de Montréal, Montréal
Québec
Canada


Christina J. Newcomb
Graduate Student, Department of Materials Science and Engineering
Institute for BioNanotechnology in Medicine
Northwestern University
Chicago


Michael L. Paine
Associate Professor, University of Southern California



Anne Poliard
Professor, University Paris Descartes
France


Megan K. Pugach
Department of Anatomy and Cell Biology
University of Pennsylvania School of Dental Medicine
240 S. 40th Street
Philadelphia
PA, 19104
USA


Anton Sculean
Professor Dr Med Dent. Chairman, Department of Periodontology
University of Bern, Freiburgstrasse 7
Bern
Switzerland


Jason L. Shapiro
Graduate Student, University of Southern California
USA


Ramaswamy Sharma Ph.D.
Postdoctoral Fellow, Forsyth Institute



Shay Sharon
Ph.D. and D.M.D. student, Hebrew University
Jerusalem
Israel


Dekel Shilo
Ph.D. and D.M.D. student, Hebrew University
Jerusalem
Israel


Nechama C. Silverstein
Ph.D. student, Hebrew University
Jerusalem
Israel


James P. Simmer
Professor, Dept. of Biologic and Materials Sciences
University of Michigan School of Dentistry
Ann Arbor
MI, 48108
USA


Jean-Yves Sire
Directeur de Recherche CNRS, Equipe “Evolution et développement du squelette”
Université Pierre et Marie Curie
UMR 7138, 7 quai Saint Bernard
Paris, 75005
France


Malcolm Snead
Professor, The University of Southern California
Center for Craniofacial Molecular Biology
2250 Alcazar Street, Clinical Science Annex 107
Los Angeles
CA, 90033
USA


Samuel I. Stupp
Professor, Department of Materials Science and Engineering
Department of Chemistry, and the Department of MedicineInstitute for BioNanotechnology in Medicine
Northwestern University, 2250 Alcazar Street
Clinical Science Annex 107
Chicago
IL
USA


Yoshiro Takano
Professor, Tokyo Medical and Dental University Graduate School
Tokyo
Japan


Kevin A. Thompkins
Assistant Prof., Departments of Oral Biology and Implantology
Faculty of Dentistry, Chulalongkorn University
Bangkok
Thailand


Coralee E. Tye
Postdoctoral Fellow, PhD Forsyth Institute



Arthur Veis
Professor emeritus, Feinberg school of Medicine
Department of Cell and Molecular Biology
Northwestern University
Chicago
IL, 60611
USA


Rima Waren
Research Assistant, Laboratory for the Study of Calcified Tissues and Biomaterials
Faculty of Dentistry, Université de Montréal, Montréal
Québec
Canada


Rungnapa Warotayanont
Resident, Department of Orofacial Sciences
University of California, San Francisco, School of Dentistry
513 Parnassus Ave S-704
San Francisco
CA, 94143-0422
USA


Shane N. White
Professor, University of California
School of Dentistry
Los Angeles
CA
USA


J. Timothy Wright
Bawden Distinguished Professor and Chair, Department of Pediatric Dentistry
School of Dentistry, The University of North Carolina
Chapel Hill
NC
USA


Yucheng Xu
Investigations performed at USC, CCMB Present Address
Senior Scientist, Investigations performed at USC, CCMB, Molecular Biology and Genomics
GlaxoSmithKline, R&D China 2F,Building 3
998 Halei Road, Zhangjiang Hi-Tech Park, Pudong
Shanghai , 201203
China


Sylvia Francis Zalzal
Laboratory Coordinator, Laboratory for the Study of Calcified Tissues and Biomaterials
Faculty of Dentistry, Université de Montréal, Montréal
Québec
Canada


Yan Zhou
Research Assistant Professor, Center for Craniofacial Molecular Biology
The University of Southern California
2250 Alcazar Street, Clinical Science Annex 107
Los Angeles
CA, 90033
USA




RELATED BOOKS

.Frontiers in Protein and Peptide Sciences.
.Gel-Forming and Soluble Mucins.
.Polarity index in Proteins-A Bioinformatics Tool.