Editors: Atta-ur-Rahman, Iqbal Choudhary

Frontiers in Anti-Cancer Drug Discovery

Volume 1

eBook: US $44 Special Offer (PDF + Printed Copy): US $363
Printed Copy: US $341
Library License: US $176
ISSN: 2451-8395 (Print)
ISSN: 1879-6656 (Online)
ISBN: 978-1-60805-626-2 (Print)
ISBN: 978-1-60805-161-8 (Online)
Year of Publication: 2010
DOI: 10.2174/97816080516181100101

Introduction

Frontiers in Anti-Cancer Drug Discovery” is an eBook series devoted to publishing the latest and the most important advances in Anti-Cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The eBook series should prove to be of interest to all pharmaceutical scientists involved in research in Anti-Cancer drug design and discovery. Each volume is devoted to the major advances in Anti-Cancer drug design and discovery. The eBook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

Indexed in: Book Citation Index, Science Edition, BIOSIS Previews, EMBASE, Chemical Abstracts, EBSCO, Ulrich's Periodicals Directory.

Contributors

Editor(s):
Prof. Dr. Atta-ur-Rahman FRS
University of Karachi
Pakistan


Prof. Dr. Iqbal Choudhary
University of Karachi
Pakistan




Contributor(s):
Nuno M.F.S.A. Cerqueira
REQUIMTE / Faculdade de Ciências do Porto
Rua Campo Alegre, 687
Porto, 4169-007
Portugal


Pedro A. Fernandes
REQUIMTE / Faculdade de Ciências do Porto
Rua Campo Alegre, 687
Porto, 4169-007
Portugal


Maria J. Ramos
REQUIMTE / Faculdade de Ciências do Porto
Rua Campo Alegre, 687
Porto, 4169-007
Portugal


Girolamo Ranieri
National Cancer Institute
Interventional Radiology Unit
Bari
Italy


Aldo Maria Roccaro
University of Bari Medical School
Bari
Italy


Angelo Vacca
Department of Biomedical Sciences and Human Oncology
University of Bari Medical School
Bari
Italy


Domenico Ribatti
Department of Human Anatomy and Histology
University of Bari Medical School
Bari
Italy


Joel D. A. Tyndall
National School of Pharmacy, University of Otago
Dunedin
New Zealand


Michael J. Kelso
School of Chemistry, University of Wollongong
NSW, 2522
Australia


Marie Ranson
School of Biological Sciences, University of Wollongong
NSW, 2522
Australia


Alfredo Budillon
Experimental Pharmacology Unit, Department of Research
National Cancer Institute "Fondazione G. Pascale"
Naples
Italy


Francesca Bruzzese
Experimental Pharmacology Unit, Department of Research
National Cancer Institute "Fondazione G. Pascale"
Naples
Italy


Elena Di Gennaro
Experimental Pharmacology Unit, Department of Research
National Cancer Institute "Fondazione G. Pascale"
Naples
Italy


Shinya Kimura
Division of Hematology, Respiratory Medicine and Oncology
Department of Internal Medicine, Faculty of Medicine
Saga University
Saga
Japan


Teresa Macarulla
Medical Oncology Department
Vall d'Hebron University Hospital
Spain


M. Elena Elez
Medical Oncology Department
Vall d'Hebron University Hospital
Spain


Francisco Javier Ramos
Medical Oncology Department
Vall d'Hebron University Hospital
Spain


Josep Tabernero
Medical Oncology Department
Vall d'Hebron University Hospital
Spain


Zeina A. Nahleh
Division of Hematology-Oncology, Karmanos Cancer Institute
Wayne State University, 4100 John R, 4HWCRC
Detroit
MI, 48201
USA


Caterina A.M. La Porta
Department of Biomolecular Science and Biotechnology
University of Milan
Milan , 20133
Italy


Mohanraj Dhanabal
EMD Serono Inc., One Technology Place
Rockland
MA, 02370
USA


Natarajan Sethuraman
GlycoFi, 21 Lafayette Street, Suite 200
Lebanon
NH, 03766-1445
USA


Luca Munaron
Department of Animal and Human Biology and Nanostructured Interfaces and Surfaces Centre of Excellence (NIS)
University of Torino, Via Accademia Albertina 13
Torino, 10123
Italy


Anna Korycka
Department of Hematology
Medical University of Lodz and Copernicus Memorial Hospital
Pabianicka 62
Lodz, 93-513
Poland


Ewa Lech-Marańda
Department of Hematology
Medical University of Lodz and Copernicus Memorial Hospital
Pabianicka 62
Lodz, 93-513
Poland


Tadeusz Robak
Department of Hematology
Medical University of Lodz and Copernicus Memorial Hospital
Pabianicka 62
Lodz, 93-513
Poland


Gabriela Melen-Mucha
Department of Immunoendocrinology
Medical University of Lodz
Kopcinskiego 22 Street
Lodz
Poland


Hanna Lawnicka
Department of Immunoendocrinology
Medical University of Lodz
Kopcinskiego 22 Street
Lodz
Poland


Dorota Kierszniewska-Stepien
Department of Pneumology and Allergology
Medical University of Lodz
Kopcinskiego 22 Street
Lodz
Poland


Jan Komorowski
Department of Clinical Endocrinology
Chair of Endocrinology, Medical University of Lodz
91-425 Lodz, Dr Sterling 3 Street
Lodz
Poland


Henryk Stepien
Department of Immunoendocrinology
Medical University of Lodz
Kopcinskiego 22 Street
Lodz
Poland


Aldo M. Roccaro
Department of Internal Medicine and Clinical Oncology
University of Bari Medical School
Bari
Italy


Angelo Vacca
Department of Internal Medicine and Clinical Oncology
University of Bari Medical School
Bari
Italy


Domenico Ribatti
Department of Human Anatomy and Histology
University of Bari Medical School
Bari
Italy


Timothy D. Wagner
Department of Radiology
Radiation Oncology Service, Brooke Army Medical Center
Fort Sam Houston
Texas
USA


Gary Y. Yang
Department of Radiation Medicine
Roswell Park Cancer Center, Buffalo
New York
USA


Irena Kostova
Department of Chemistry, Faculty of Pharmacy
Medical University, 2 Dunav St.
Sofia, 1000
Bulgaria


Sam Robson
Biological Sciences
Biomedical Research Institute
University of Warwick, CV4 7AL
Coventry
UK


Inga Pukonen
Biological Sciences
Biomedical Research Institute
University of Warwick, CV4 7AL
Coventry
UK


Sylvie Abouna
Biological Sciences
Biomedical Research Institute
University of Warwick, CV4 7AL
Coventry
UK


Stella Pelengaris
Biological Sciences
Biomedical Research Institute
University of Warwick, CV4 7AL
Coventry
UK


Michael Khan
Biological Sciences
Biomedical Research Institute
University of Warwick, CV4 7AL
Coventry
UK


Sui Xiong Cai
IMPACT Therapeutics, Inc.
10 Xinghuo Road, Floor 9, High
New Technology Zone, Nanjing
Jiangsu, 210061
China


Piotr Rutkowski
Department of Soft Tissue/Bone Sarcoma and Melanoma
M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology
Warsaw
Poland


Małgorzata Symonides
Department of Anesthesiology
M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology
Warsaw
Poland


Marcin Zdzienicki
Department of Soft Tissue/Bone Sarcoma and Melanoma
M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology
Warsaw
Poland


Janusz A. Siedlecki
Department of Anesthesiology
M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology
Warsaw
Poland


Helmut Deissler
Department of Obstetrics and Gynecology
University of Ulm Medical School
Ulm
Germany


Bertram Opalka
Department of Obstetrics and Gynecology
University of Ulm Medical School
Ulm
Germany


Shahar Lev-Ari
Department of Cancer Prevention
Tel Aviv Medical Center; The Sackler Faculty of Medicine
Tel Aviv University
Israel


Dov Lichtenberg
The Sackler Faculty of Medicine
Tel Aviv University
Israel


Nadir Arber
Department of Cancer Prevention
Tel Aviv Medical Center;
The Sackler Faculty of Medicine
Tel Aviv University
Israel


Yukio Kageyama
Department of Urology
Saitama Cancer Center
Saitama, 362-0806
Japan
/
Department of Urology
Graduate School Tokyo Medical and Dental University
Tokyo, 113-8519
Japan


Nobuhiko Hyochi
Department of Urology
Graduate School Tokyo Medical and Dental University
Tokyo, 113-8519
Japan


Kazunori Kihara
Department of Urology
Graduate School Tokyo Medical and Dental University
Tokyo, 113-8519
Japan


Hiroshi Sugiyama
Department of Chemistry
Graduate School of Science, Kyoto University
Kyoto, 606-8502
Japan


Tadeusz Robak
Department of Hematology
Medical University of Lodz and Copernicus Memorial Hospital
93-513 Lodz, Pabianicka 62, 606-8502
Poland


Anna Korycka
Department of Hematology
Medical University of Lodz and Copernicus Memorial Hospital
93-513 Lodz, Pabianicka 62, 606-8502
Poland


Ewa Robak
Department of Dermatology
Medical Uniwersity of Lodz
94-017 Lodz, Krzemieniecka 5
Poland


Lars P. Jordheim
Laboratoire de Cytologie Analytique – INSERM U590
Université Claude Bernard Lyon 1, Lyon
France


Charles Dumontet
Laboratoire de Cytologie Analytique – INSERM U590
Université Claude Bernard Lyon 1, Lyon
France


Rakesh Kumar
Department of Nuclear Medicine
All India Institute of Medical Sciences
Ansari nagar
India


Dhanpathi Halanaik
Department of Nuclear Medicine
All India Institute of Medical Sciences
Ansari nagar
India


Saurabh Dahiya
Department of Nuclear Medicine
All India Institute of Medical Sciences
Ansari nagar
India


Amr Amin
Biology Department
College of Science, UAE University
UAE


Michael Buratovich
Department of Biochemistry
Spring Arbor University
MI, 49283
USA


Joanne M. Bowen
Department of Medical Oncology
Royal Adelaide Hospital, and School of Medicine
University of Adelaide, South Australia
Adelaide, 5000
Australia


Arsenio M. Fialho
Instituto for Biotechnology and BioEngineering (IBB)
Center for Biological and Chemical Engineering
Institute Superior Tecnico
Lisbon, 1049-001
Portugal


Ananda M. Chakrabarty
Department of Microbiology and Immunology
University of Illinois College of Medicine
835 South Wolcott Avenue
Chicago
IL, 60612
USA


Xun Li
Department of Medicinal Chemistry
School of Pharmaceutical Sciences, Shandong University, Ji’nan
Shandong Province, 250012
P.R. China


Yalin Li
State Intellectual Property Office of China
Beijing, 100088
P.R. China


Wenfang Xu
Department of Medicinal Chemistry
School of Pharmaceutical Sciences, Shandong University, Ji’nan
Shandong Province, 250012
P.R. China


Mark N. Kirstein
Department of Experimental and Clinical Pharmacology
College of Pharmacy and Masonic Comprehensive Cancer Center
University of Minnesota
USA


Arkadiusz Z. Dudek
Department of Medicine and Masonic Comprehensive Cancer Center
University of Minnesota
USA


Paul K. Wright
Department of Histopathology
Clinical Sciences Building
1 Floor, Manchester Royal Infirmary, Oxford Road
Manchester, M13 9WL
UK




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