Editors: Akhlaq Farooqui , Tahira Farooqui

Molecular Aspects of Neurodegeneration and Neuroprotection

eBook: US $61 Special Offer (PDF + Printed Copy): US $140
Printed Copy: US $110
Library License: US $244
ISBN: 978-1-60805-376-6 (Print)
ISBN: 978-1-60805-092-5 (Online)
Year of Publication: 2011
DOI: 10.2174/97816080509251110101

Introduction

Neurodegenerative diseases are a complex heterogeneous group of diseases associated with site-specific premature and slow death of certain neuronal populations in brain and spinal cord tissues. For example, in Alzheimer disease, neuronal degeneration occurs in the nucleus basalis, whereas in Parkinson disease, neurons in the substantia nigra die. The most severely affected neurons in Huntington disease are striatal medium spiny neurons. The neuronal populations that are lost in neurodegenerative diseases modulate functions such as controlling movements, processing sensory information, memory, and making decisions. Although, the molecular mechanism of neurodegeneration remains unknown, but excitotoxicity, inflammation, and oxidative stress may contribute to neural cell demise independently or synergistically. The purpose of this E-book is to present readers with cutting edge and comprehensive information on molecular aspects of neurodegenerative diseases and neuroprotection in a manner that is useful not only to students and teachers, but also to researchers and physicians.

Foreword

- Pp. i
Lane J. Wallace
Download Free

Preface

- Pp. ii
Akhlaq A. Farooqui and Tahira Farooqui
Download Free

Contributors

- Pp. iii-v (3)
Akhlaq A. Farooqui and Tahira Farooqui
View Abstract Download Free

Acknowledgements

- Pp. vi
Akhlaq A. Farooqui and Tahira Farooqui
Download Free

Arachidonic Acid and Docosahexaenoic Acid-derived Lipid Mediators in Brain

- Pp. 1-9 (9)
Akhlaq A. Farooqui

PDF Price: $15

View Abstract Purchase Chapter

Neurochemical Aspects of Inflammation in Brain

- Pp. 10-22 (13)
Akhlaq A. Farooqui

PDF Price: $15

View Abstract Purchase Chapter

Suitable Biomarkers of Oxidative Stress in Neurodegenerative Diseases

- Pp. 23-38 (16)
Fabio Coppedea and Lucia Miglioreb

PDF Price: $15

View Abstract Purchase Chapter

Kainic Acid-Mediated Neural Cell Death in Brain: Interplay Among Glycerophospholipid-, Sphingolipid-, and Cholesterol-Derived Lipid Mediators

- Pp. 39-49 (11)
Wei-Yi Ong and Akhlaq A. Farooqui

PDF Price: $15

View Abstract Purchase Chapter

Association of Mitochondrial Signaling in Alzheimer’s Disease and Hypoxia

- Pp. 50-61 (12)
Cristina Carvalho, Sonia C. Correia, Renato X. Santos, Susana Cardoso, Paula I. Moreira, Xiongwei Zhu, Mark A. Smith and George Perry

PDF Price: $15

View Abstract Purchase Chapter

Dopamine-Mediated Oxidative Stress Associated with Neurodegeneration in Parkinson Disease

- Pp. 62-71 (10)
Tahira Farooqui

PDF Price: $15

View Abstract Purchase Chapter

Contribution of Complement in Neurodegenerative and Neuroinflammatory Diseases

- Pp. 72-89 (18)
Annapurna Nayak, Uday Kishore and DM Bonifati

PDF Price: $15

View Abstract Purchase Chapter

The Roles of Platelet-Activating Factor (PAF) and its Related Signaling and Metabolism in Neurological Diseases

- Pp. 90-101 (12)
Yutaka Hirashima

PDF Price: $15

View Abstract Purchase Chapter

Novel Mechanism for Oxidative Stress in Neurodevelopmental Pathophysiology and Course of Schizophrenia

- Pp. 102-120 (19)
Anvita Kale, Sadhana R. Joshi and Sahebarao P. Mahadik

PDF Price: $15

View Abstract Purchase Chapter

Neuroprotective Actions of Polyunsaturated Fatty Acids with Particular Reference to Alzheimer’s Disease

- Pp. 121-131 (11)
Undurti N Das

PDF Price: $15

View Abstract Purchase Chapter

Future Perspective: Directions for Future Development on Various Aspects of Neurodegeneration and Neuroprotection in Neurological Disorders

- Pp. 132-139 (8)
Akhlaq A. Farooqui and Tahira Farooqui

PDF Price: $15

View Abstract Purchase Chapter

Index

- Pp. 140-146 (7)
Akhlaq A. Farooqui and Tahira Farooqui
View Abstract Download Free

RELATED BOOKS

.Frontiers in Clinical Drug Research-Dementia.
.Alzheimer
.Advances in Alzheimer Research.
.Cellular and Molecular Biology of Autism Spectrum Disorders.
.Alzheimer
.Advances in Alzheimer Research.
.Cellular and Molecular Biology of Autism Spectrum Disorders.
.Cellular Mechanisms in Alzheimer’s Disease.