Editor: Liang Qiao

Molecular Aspects of Hepatocellular Carcinoma

eBook: US $99 Special Offer (PDF + Printed Copy): US $168
Printed Copy: US $119
Library License: US $396
ISBN: 978-1-60805-378-0 (Print)
ISBN: 978-1-60805-072-7 (Online)
Year of Publication: 2012
DOI: 10.2174/97816080507271120101

Introduction

Therapeutic options for late-stage liver cancer are very limited and the prognosis is often poor. A better understanding of the molecular mechanisms involved in the initiation, progression, and metastasis of hepatocellular carcinoma is critical for developing more rational diagnostic and therapeutic approaches. This e-book covers current developments on clinically relevant research on the molecular biology of hepatocellular carcinoma. It should be a valuable reference for professional gastroenterologists, hepatologists and oncologists as well as medical students and researchers.

Foreword

- Pp. i
Morris Sherman
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Preface

- Pp. ii-iii (2)
Liang Qiao, Yumin Li, Xiang Yan and Jacob George
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List of Contributors

- Pp. iv-vi (3)
Liang Qiao, Yumin Li, Xiang Yan and Jacob George
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Acknowledgements

- Pp. vii
Liang Qiao, Yumin Li, Xiang Yan and Jacob George
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The Relationship between Liver Fibrosis and Hepatocellular Carcinoma

- Pp. 3-7 (5)
Hai Li and Ji-D. Jia

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A Possible Link between Non-Alcoholic Steatohepatitis and Hepatocellular Cancer

- Pp. 8-20 (13)
Elisabetta Bugianesi and Federico Salamone

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Viral Associated Hepatocellular Carcinoma

- Pp. 21-31 (11)
Alfred S.-L. Cheng and Henry L.-Y. Chan

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Non-Viral Cause of Liver Cirrhosis: Do they Lead to Hepatocellular Carcinoma?

- Pp. 32-38 (7)
Yuan-W. Chen and Jian-G. Fan

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Signaling Pathways Involved in Molecular Carcinogenesis of Hepatocellular Carcinoma

- Pp. 39-55 (17)
Tatsuo Kanda, Fumio Imazeki, Fumihiko Kanai, Motohisa Tada, Osamu Yokosuka and Masao Omata

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MicroRNAs in Human Hepatocellular Carcinoma

- Pp. 56-66 (11)
Wilson K.C. Leung and Nathalie Wong

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Characteristics of Liver Stem/Progenitor Cells and their Relation to Cancer: Response to Inflammatory and Cell Death Signals

- Pp. 67-79 (13)
Cornelia S. Viebahn, Bernard Callus and George C.T. Yeoh

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Aging and Hepatocellular Carcinoma: Possible Molecular Mechanisms

- Pp. 80-85 (6)
Aiping Tian, Liang Qiao and Xiang Yan

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Molecular Mechanisms of Liver Cancer Metastasis

- Pp. 86-105 (20)
Maria L. Balmer and Jean-F. Dufour

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Biomarkers for Diagnosis and Surveillance in Hepatocellular Carcinoma

- Pp. 106-115 (10)
Thomas Wex, Kerstin Schutte, Jan Bornschein and Peter Malfertheiner

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Animal Models of Hepatocellular Carcinoma

- Pp. 116-128 (13)
Sarah L. Walker, Jacob George and Lionel W. Hebbard

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Chemoprevention of Hepatocellular Carcinoma

- Pp. 129-137 (9)
Massimo Colombo

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An Overview on Molecular Therapy for Hepatocellular Carcinoma

- Pp. 138-148 (11)
Quanda Liu, Yongning Zhou, Zenan Hu and Liang Qiao

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Role of Angiogenesis in HCC Development and Therapy

- Pp. 149-161 (13)
Lionel W. Hebbard

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Non-Surgical Management of Hepatocellular Carcinoma: Possible Mechanisms

- Pp. 162-166 (5)
Yumin Li, Wenting He, Tao Liu and Yingtai Chen

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Treatment of Hepatocellular Carcinoma with Traditional Chinese Medicine: Possible Molecular Mechanisms

- Pp. 167-173 (7)
Cai-Y. Zhao, Xiaoyu Liu, Chuan Shen, Yadong Wang and Liang Qiao

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Randomised Controlled Trials in the Primary Treatment of Hepatocellular Carcinoma

- Pp. 174-195 (22)
Monica Robotin

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Subject Index

- Pp. 196-199 (4)
Liang Qiao, Yumin Li, Xiang Yan and Jacob George
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