Editor: Sandra Hodge

Lung Macrophages in Health and Disease

eBook: US $49 Special Offer (PDF + Printed Copy): US $113
Printed Copy: US $89
Library License: US $196
ISBN: 978-1-60805-314-8 (Print)
ISBN: 978-1-60805-020-8 (Online)
Year of Publication: 2009
DOI: 10.2174/97816080502081090101

Introduction

This Ebook is edited by Sandra Hodge, a recognized expert in the field of macrophage dysfunction in chronic lung disease. The book consists of 8 chapters which provide a full coverage of macrophage function in both healthy and chronically diseased lungs, starting with the regulation of macrophage homoestasis to altered macrophage recognition and clearance of pathogens and apoptotic cells in the lung before moving on to macrophage targeted treatment options for chronic lung diseases. The important problem of oxidative and carbonyl stress in the lung and its impact on macrophage function is discussed. Additional chapters deal with the role of disordered macrophage function in cancer progression and the role of chronic alcohol ingestion of macrophage function. Importantly, the book integrates both respiratory cell biology and clinical medicine. The concept of failed macrophage function with regard to chronic lung disease has recently been the topic of intensive research. Key advances in our knowledge of the cellular and molecular mechanisms involved in defective macrophage function have paved the way for the development of novel diagnostic and therapeutic strategies for diseases such as chronic obstructive pulmonary disease and asthma. For this reason the book can be recommended without reservation to a wide spectrum of readers including students, respiratory cell biologists and respiratory clinicians.

Contributors

Editor(s):
Sandra Hodge
University of Adelaide
Australia




Contributor(s):
S.W. Glasser
Associate Professor of Pediatrics, Cincinnati Children’s Hospital Medical Center
University of Cincinnati, College of Medicine
Cincinnati
Ohio
USA


A.P. Senft
Lovelace Respiratory Research Institute
Infectious Diseases Program, Albuquerque
New Mexico
USA


Tracey L. Bonfield
Assistant Professor and Director of The Inflammatory Mediator CORE, Department of Pediatrics
Case Western Reserve University, Cleveland
Ohio
USA


Robert D. Stout
Professor, Department of Microbiology and Immunology
University of Louisville School, of Medicine and James Graham Brown Cancer Cente
Louisville
KY
USA


Jill Suttles
Professor, Department of Microbiology and Immunology
University of Louisville School, of Medicine and James Graham Brown Cancer Center
Louisville
KY
USA


Carol Anne Ogden
Immuno-Inflammation Center for Excellence in Drug Discovery
GlaxoSmithKline, Pharmaceuticals
Philadelphia
Pennsylvania
USA


Abigail E. Taylor
Senior Lecurer, Airway Disease, National Heart and Lung Institute
London
UK


Louise E. Donnelly
Senior Lecurer, Airway Disease, National Heart and Lung Institute
London
UK


Paul Kirkham
Royal Society Fellow & Honorary Senior Lecturer
National Heart and Lung Institute, Imperial College
London
UK


Pratibha C. Joshi
Assistant Professor of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine
Emory University and Atlanta VAMC
Decatur
GA
USA


Paul N. Reynolds
Consultant Physician in Respiratory and Sleep Medicine, Department of Thoracic Medicine
Royal Adelaide Hospital
South Australia




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.
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