Editor: Sandra Hodge

Lung Macrophages in Health and Disease

eBook: US $49 Special Offer (PDF + Printed Copy): US $113
Printed Copy: US $89
Library License: US $196
ISBN: 978-1-60805-314-8 (Print)
ISBN: 978-1-60805-020-8 (Online)
Year of Publication: 2009
DOI: 10.2174/97816080502081090101


This Ebook is edited by Sandra Hodge, a recognized expert in the field of macrophage dysfunction in chronic lung disease. The book consists of 8 chapters which provide a full coverage of macrophage function in both healthy and chronically diseased lungs, starting with the regulation of macrophage homoestasis to altered macrophage recognition and clearance of pathogens and apoptotic cells in the lung before moving on to macrophage targeted treatment options for chronic lung diseases. The important problem of oxidative and carbonyl stress in the lung and its impact on macrophage function is discussed. Additional chapters deal with the role of disordered macrophage function in cancer progression and the role of chronic alcohol ingestion of macrophage function. Importantly, the book integrates both respiratory cell biology and clinical medicine. The concept of failed macrophage function with regard to chronic lung disease has recently been the topic of intensive research. Key advances in our knowledge of the cellular and molecular mechanisms involved in defective macrophage function have paved the way for the development of novel diagnostic and therapeutic strategies for diseases such as chronic obstructive pulmonary disease and asthma. For this reason the book can be recommended without reservation to a wide spectrum of readers including students, respiratory cell biologists and respiratory clinicians.


- Pp. i
William Vandivier
Download Free


- Pp. ii
Sandra Hodge
Download Free


- Pp. iii-iv (2)
Sandra Hodge
Download Free

Pulmonary Surfactant Homeostasis and Altered Macrophage Function

- Pp. 1-13 (13)
S. W. Glasser, A. P. Senft
View Abstract

Regulation of Macrophage Homeostasis

- Pp. 14-36 (23)
Tracey L Bonfield
View Abstract

Macrophage Functional Plasticity: Implications for Cancer Progression and Therapy

- Pp. 37-51 (15)
Robert D. Stout, Jill Suttles
View Abstract

Critical Clearance: Alveolar Macrophage Recognition of Apoptotic Cells

- Pp. 52-61 (10)
Carol Anne Ogden
View Abstract

Defective Clearance of Apoptotic Cells (Efferocytosis) in Chronic Lung Diseases

- Pp. 62-75 (14)
Sandra Hodge
View Abstract

Role of Macrophage Phagocytosis of Bacterial Pathogens in Chronic Lung Disease

- Pp. 76-87 (12)
Abigail E Taylor, Louise E Donnelly
View Abstract

The Impact of Oxidative and Carbonyl Stress on Cell Function: Functional Consequences for Macrophages

- Pp. 88-98 (11)
Paul Kirkham
View Abstract

The Effects of Chronic Alcohol Ingestion on Alveolar Macrophage Function

- Pp. 99-106 (8)
Pratibha C. Joshi
View Abstract

Novel Therapeutic Approaches to Improve Efferocytosis for Pulmonary Disease

- Pp. 107-117 (11)
Paul N. Reynolds
View Abstract


- Pp. 118-119 (2)
Sandra Hodge
Download Free


- Pp. 120
Sandra Hodge
Download Free


.A Case-Based Approach to Interventional Pulmonology: A Focus on Asian Perspectives.
.Advances in Interventional Pulmonology.
.Lung Function in Health and Disease Basic Concepts of Respiratory Physiology and Pathophysiology