Editors: Atta-ur-Rahman, Mohammad Iqbal Choudhary

Drug Design and Discovery in Alzheimer’s Disease

Republished Version of Frontiers in Drug Design and Discovery Volume 6

Personal Book: US $165 Special Offer (PDF + Printed Copy): US $317
Printed Copy: US $235
Library Book: US $660
ISSN: 1574-0889
eISSN: 2212-1064 (Online)
ISBN: 978-0-12-803959-5
eISBN: 978-012-803960-1 (Online)
Year of Publication: 2014
DOI: 10.1016/c2014-0-04317-1

Introduction

“Frontiers in Drug Design and Discovery” is an Ebook series devoted to publishing the latest and the most important advances in drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. The Ebook series should prove to be of interest to all the pharmaceutical scientists involved in research in drug design and discovery. Each volume is devoted to the major advances in drug design and discovery. The Ebook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

The sixth volume of this Ebook series focuses on drug discovery and design strategies for the treatment of Aheimer’s Diseases and related neurodegenerative disorders.

Indexed in: Book Citation Index, Science Edition, BIOSIS Previews, Scopus, EMBASE, EBSCO, Ulrich's Periodicals Directory.

Contributors

Editor(s):
Atta-ur-Rahman
University of Cambridge
Cambridge
UK


Mohammad Iqbal Choudhary
H.E.J. Research Institute of Chemistry
International Center for Chemical and Biological Sciences
University of Karachi
Karachi
Pakistan




Contributor(s):
A. Michael Crider
Faculty of Medicine and Health Sciences
United Arab Emirates University
Department Pharmacology and Therapeutics
Al Ain
UAE


Abdu Adem
Faculty of Medicine and Health Sciences
United Arab Emirates University
Department Pharmacology and Therapeutics
Al Ain
UAE


Adel M. Abuzenadah
King Fahd Medical Research Center
King Abdulaziz University
P. O. Box 80216
Jeddah, 21589
Saudi Arabia


Ali Jawad
Department of Applied Physics
Zakir Husain College of Engineering and Technology
Aligarh Muslim University
Aligarh UP
India


Benjamin P. Repsold
Pharmaceutical Chemistry
North-West University
Private Bag X6001
Potchefstroom, 2520
South Africa


Boris Decourt
Banner Sun Health Research Institute
Sun City
AZ
USA


Carmen Martínez-Rincón
Nursing Department
Complutense University of Madrid
Spain


Daniel Jun
University Hospital Hradec Kralove
Sokolska 581
500 05 Hradec Kralove
Czech Republic


Darrick Pope
Department of Chemistry and Biochemistry
Duquesne University
Pittsburgh
PA, 15282
USA


David F. Fischer
BioFocus
Leiden
The Netherlands


David William Klaver
Department of Neuroscience
Alzheimer’s Disease Research Laboratory
Tufts University School of Medicine
Boston
MA
USA


Dolores Rodríguez-Martínez
Nursing Department
Complutense University of Madrid
Spain


Eric A. Owens
Department of Chemistry
Center for Diagnostics and Therapeutics
Georgia State University
Georgia
Atlanta, 30303
USA


Eugenie Nepovimova
Department of Toxicology
Faculty of Military Health Sciences
Trebesska 1575, 500 01
Hradec Kralove
Czech Republic


Faizul H. Nasim
Department of Chemistry, BJ Campus
The Islamia University of Bahawalpur
Bahawalpur
Pakistan


Fares Zeidán-Chuliá
Center of Oxidative Stress Research
Department of Biochemistry
Postgraduate Program in Biological Sciences
Biochemistry
Institute of Basic Health Sciences
Federal University of Rio Grande do Sul
Porto Alegre
RS
Brazil


Farhan Jalees Ahmad
Nanomedicine Research Lab
Department of Pharmaceutics
Faculty of Pharmacy
Jamia Hamdard
New Delhi 110062
India


Farzana L. Ansari
Department of Chemistry
Quaid-i-Azam University
Islamabad 45320
Pakistan


Filip Zemek
Department of Toxicology
Faculty of Military Health Sciences
Trebesska 1575
500 01 Hradec Kralove
Islamabad 45320
Czech Republic


Giuseppina Tesco
Alzheimer’s Disease Research Laboratory
Department of Neuroscience
Tufts University School of Medicine
500 01 Hradec Kralove
Boston
MA
USA


Gjumrakch Aliev
Department of Health Science and Healthcare Administration
University of Atlanta
Atlanta
GA
USA
/
GALLY International Biomedical Research Consulting LLC
University of Atlanta
San Antonio
TX
USA


Iqbal Ahmad
Nanomedicine Research Lab, Department of Pharmaceutics
Faculty of Pharmacy
Jamia Hamdard
New Delhi, 110062
India


Ismael Ortuño- Soriano
Institute for Health Research at the San Carlos Clinical Hospital (IdISSC)
Madrid
Spain
/
Nursing Department
Complutense University of Madrid
Madrid
Spain


Jacobus P. Petzer
Pharmaceutical Chemistry
North-West University
Private Bag X6001
Potchefstroom
South Africa


Jacques Joubert
School of Pharmacy
University of the Western Cape
Private Bag X17
Bellville, 7535
South Africa


Jan Korabecny
Department of Toxicology
Faculty of Military Health Sciences
Trebesska 1575
500 01 Hradec Kralove
Czech Republic


Javed Ahmad
Nanomedicine Research Lab
Department of Pharmaceutics, Faculty of Pharmacy
Jamia Hamdard
New Delhi, 110062
India


José Cláudio Fonseca Moreira
Center of Oxidative Stress Research
Department of Biochemistry
Postgraduate Program in Biological Sciences: Biochemistry
Institute of Basic Health Sciences
Federal University of Rio Grande do Sul
Porto Alegre
RS
Brazil


José L. Pacheco-del-Cerro
Nursing Department
Complutense University of Madrid
Madrid
Spain


Julie Frearson
BioFocus; Chesterford Research Park
Saffron Walden
Essex, CB10 1XL
UK


Kamil Kuca
University Hospital Hradec Kralove
Sokolska 581
500 05 Hradec Kralove
Czech Republic


Kamil Musilek
University Hospital Hradec Kralove
Sokolska 581
500 05 Hradec Kralove
Czech Republic


Karin E. Sandoval
Department of Pharmaceutical Sciences
Southern Illinois University Edwardsville
Edwardsville
Illinois, 62026
USA


Katarina Spilovska
Department of Toxicology
Faculty of Military Health Sciences
Trebesska 1575
500 01 Hradec Kralove
Czech Republic


Kenneth Witt
Department of Pharmaceutical Sciences
Southern Illinois University Edwardsville
Edwardsville
Illinois, 62026
USA


Lara Pacheco-Cuevas
Nursing Department
Complutense University of Madrid
Spain


Louis H.A. Prins
Department of Pharmacy
University of Namibia
Windhoek
Namibia


Maged M. Henary
Department of Chemistry, Center for Diagnostics and Therapeutics
Center for Biotechnology and Drug Design, Georgia State University
Georgia
Atlanta, 30303
USA


Maria Kontoyianni
Department of Pharmaceutical Sciences
Southern Illinois University Edwardsville
Edwardsville
Illinois, 62026
USA


Marwan Sabbagh
Banner Sun Health Research Institute
Sun City
AZ
USA


Mauricio Alcolea-Palafox
Chemical-Physics Department
Chemistry Faculty
Complutense University of Madrid
Madrid
Spain


Michael Cascio
Department of Chemistry and Biochemistry
Duquesne University
Pittsburgh
PA, 15282
USA


Michael D. Wall
BioFocus; Chesterford Research Park
Saffron Walden
Essex, CB10 1XL
UK


MiMi Macias
Banner Sun Health Research Institute
Sun City
AZ
USA


Mohamed A. Embaby
Department of Chemistry
Faculty of Sciences & Arts Khulais
King Abdulaziz University
Jeddah
KSA


Mohammad A. Kamal
King Fahd Medical Research Center
King Abdulaziz University
P. O. Box 80216
Jeddah, 21589
Saudi Arabia


Mohamed Zaki Ahmad
Department of Pharmaceutics
College of Pharmacy
Najran University
Saudi Arabia


Nasimudeen R. Jabir
King Fahd Medical Research Center
King Abdulaziz University
P. O. Box 80216
Jeddah, 21589
Saudi Arabia


Nigel H. Grieg
Drug Design & Development Section
Laboratory of Neurosciences
Intramural Research Program
National Institute on Aging
National Institutes of Health
Baltimore
MD 21224
USA


Mohamed Nighat Sultana
Pharmaceutical Research Center
PCSIR Laboratories Complex
Shahrah-e-Dr. Salimuzzaman Siddiqui
Karachi, 75280
Pakistan


Omar Aziz
Pharmaceutical Research Center
BioFocus; Chesterford Research Park
Saffron Walden
Essex, CB10 1XL
UK


Ondrej Soukup
University Hospital Hradec Kralove
Sokolska 581
500 05 Hradec Kralove
Czech Republic


Othman Sulaiman
School of Industrial Technology
Universiti Sains Malaysia
Pulau Pinang
Minden–11800
Malaysia


Paloma Posada-Moreno
Institute for Health Research at the San Carlos Clinical Hospital (IdISSC)
Madrid
Spain
/
Nursing Department
Complutense University of Madrid
Madrid
Spain


Pierfausto Seneci
Department of Chemistry
University of Milan
Via Golgi 19
I-20133 Milan
Italy


Raza Murad Ghalib
Department of Chemistry
Faculty of Sciences & Arts Khulais
King Abdulaziz University
Jeddah
KSA


Rokiah Hashim
School of Industrial Technology
Universiti Sains Malaysia
Pulau Pinang
Minden–11800
Malaysia


Sarel F. Malan
School of Pharmacy
University of the Western Cape
Private Bag X17
Bellville, 7535
South Africa


Sayed Hasan Mehdi
Department of Chemistry
SPG College
Lucknow
UP
India


Shams Tabrez
King Fahd Medical Research Center
King Abdulaziz University
P. O. Box 80216
Jeddah, 21589
Saudi Arabia


Sohail Akhter
Nanomedicine Research Lab
Department of Pharmaceutics, Faculty of Pharmacy
Jamia Hamdard
New Delhi, 110062
India


Surendra Reddy Punganuru
Department of Chemistry
Georgia State University
Georgia
Atlanta, 30303
USA


Tyler L. Dost
Department of Chemistry
Georgia State University
Georgia
Atlanta, 30303
USA


Umer Rashid
Department of Chemistry
Hazara University
Mansehra, 21120
Pakistan


Vageesh Revadigar
Discipline of Pharmacology
School of Pharmaceutical Sciences
Universiti Sains Malaysia
Pulau Pinang
Minden–11800
Malaysia


Vikneswaran Murugaiyah
Discipline of Pharmacology, School of Pharmaceutical Sciences
Universiti Sains Malaysia
Minden–11800
Pulau Pinang
Malaysia


Zafar Saied Saify
International Center for Chemical Sciences
H. E. J. Research Institute of Chemistry
University of Karachi
Karachi, 75270
Pakistan


Ziyaur Rahman
Irma Lerma Rangel College of Pharmacy
Texas A&M Health Science Center
Kingsville
Texas
USA




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