Editors: Shruti Mishra, Rupesh Chaturvedi, Achyut Pandey

Host-Pathogen Interactions in Humans: Mechanisms, Implications, and Therapeutic Strategies

eBook: US $99 Special Offer (PDF + Printed Copy): US $179
Printed Copy: US $129
Library License: US $396
ISBN: 979-8-89881-811-1 (Print)
ISBN: 979-8-89881-810-4 (Online)
Year of Publication: 2026
DOI: 10.2174/97988988181041260101

Introduction

Host-pathogen interactions are central to understanding how infectious diseases develop and how the human immune system responds to invading microorganisms. Knowledge of these interactions provides a foundation for developing effective approaches to infection prevention, diagnosis and treatment.

Host-Pathogen Interactions in Humans: Mechanisms, Implications, and Therapeutic Strategies provides a structured overview of the cellular and molecular mechanisms underlying host defense and pathogen survival. The book examines bacterial, viral, fungal and parasitic infections along with chronic infections, co-infections, inflammatory responses and immune pathologies. Chapters also explore the role of the microbiome in shaping host-pathogen relationships and discusses therapeutic approaches including antimicrobial therapies, vaccines, immunotherapy and immune modulation. Emerging infectious diseases and the application of artificial intelligence in host-pathogen research are also addressed, providing perspectives on current developments and future research directions.


Key Features

  • - Explains cellular and molecular mechanisms of host defense.
  • - Covers bacterial, viral, fungal and parasitic infections.
  • - Examines microbiome interactions, co-infections and immune responses.
  • - Discusses antimicrobial therapies, vaccines and immunotherapy.
  • - Explores AI applications and emerging directions in host-pathogen research.
  • - Structured chapters for easy understanding and quick reference.

Target Readership :

Researchers, scholars and educators in the field of microbiology and life sciences.

Foreword

- Pp. i
Kumar Sarvottam*
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Preface

- Pp. ii
Shruti Mishra, Rupesh Chaturvedi, Achyut Pandey
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List of Contributors

- Pp. iii-v (3)

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Introduction to Host-Pathogen Interactions

- Pp. 1-19 (19)
Swastick Bisht, Roshni Mishra, Shruti Mishra*

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Cellular and Molecular Mechanism of Host Defense

- Pp. 20-38 (19)
Poonam P. Ghate*, Deepak Khobragade, D. Suja Rani, Anjitha Anil Pillai

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Pathogen Invasion and Human Host Evasion Strategies

- Pp. 39-53 (15)
Swastick Bisht, Shruti Mishra*

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Bacterial-Pathogen Interactions with the Human Host

- Pp. 54-80 (27)
Shyam Tripathi, Kusum Rani, Diksha Dahiya, Sheetal Kundu, Meher Rizvi, V. Samuel Raj*

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Viral Pathogen Interaction with the Human Host

- Pp. 81-99 (19)
Arun MT, Aneesh Nair*

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Fungal and Parasitic Infections in Humans

- Pp. 100-125 (26)
Rajesh Yadav*

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Chronic Infection and Host-Pathogen Coevolution

- Pp. 126-148 (23)
Rajesh Yadav*

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Inflammatory Responses and Immune Pathologies

- Pp. 149-174 (26)
Palnati Nandini Reddy, Kalaivani M Kuppusamy, Prasanna Raja*, Ramanaiah Illuri

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The Microbiome’s Role in Host-Pathogen Interactions

- Pp. 175-213 (39)
Priyanka Gautam, Rahul Yadav, Chandan Singh, Abhishek Pathak*

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Development of Antimicrobial Therapies

- Pp. 214-245 (32)
Vandana Kumari, Kalpana Singh, Ankita Sharma, Pratibha Singh*

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Advances in Vaccine Development

- Pp. 246-262 (17)
Bhumika Singh, Supriya Pal, Shruti Nirwal, Savitri Tiwari*

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Immunotherapy and Immune Modulation

- Pp. 263-300 (38)
Sacheen Kumar, Achyut Pandey*

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Host-Pathogen Interaction in Emerging Infectious Diseases

- Pp. 301-329 (29)
Tarun Kumar Upadhyay*, Adil Ali

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Artificial Intelligence in Host-Pathogen Interaction

- Pp. 330-365 (36)
Shreya Mishra, Sacheen Kumar, Achyut Pandey*

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Future Directions in Host Pathogen Research

- Pp. 366-388 (23)
Kajal, Amit K. Gupta*

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Subject Index

- Pp. 389-393 (5)
Shruti Mishra, Rupesh Chaturvedi, Achyut Pandey
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