Nanocarrier-based Drug Delivery for the Management of Fatty Liver Disease

Editors: Anjali Sharma, Devkant Sharma, Ajmer Singh Grewal, Geeta Deswal, Ganga Reddy Velma

Nanocarrier-based Drug Delivery for the Management of Fatty Liver Disease

ISBN: 979-8-89881-568-4
eISBN: 979-8-89881-567-7 (Online)

Introduction

Nanocarrier-based Drug Delivery for the Management of Fatty Liver Disease is an advanced exploration of nanotechnology-driven therapeutic strategies for the diagnosis and treatment of fatty liver disease that is positioned at the intersection of nanomedicine, pharmacology, hepatology, and drug delivery.

The book begins with foundational concepts of fatty liver disease and its metabolic implications before introducing various nanocarrier-based drug delivery systems and liver-targeting strategies. Dedicated chapters discuss lipid-based nanocarriers, polymeric nanoparticles, dendrimers, and hybrid nanocarrier systems for therapeutic applications. It further explores novel therapeutics, nanocarrier-based imaging agents for diagnosis, pharmacokinetics and pharmacodynamics, and the safety and toxicity aspects of nanomedicine. Clinical translation, real-world case studies, and emerging trends in nanocarrier-assisted liver disease management are also comprehensively examined.


Key Features

  • - Comprehensive coverage of nanocarrier systems for fatty liver disease treatment.
  • - Discussions of lipid-based, polymeric, dendrimer, and hybrid nanocarriers.
  • - Insights into liver-targeted drug delivery and imaging technologies.
  • - Coverage of pharmacokinetics, toxicity, and clinical translation challenges.
  • - Focuses on emerging therapeutic strategies and future developments in nanomedicine.

Target Readership :

Researchers, clinicians, pharmacologists, scientists, postgraduate students, and academics in hepatology, pharmaceutical sciences, nanomedicine, drug delivery, and biomedical research.

Preface

Fatty liver disease has become a serious public health problem due to the rise in instances of obesity, diabetes, and associated metabolic diseases worldwide. Effective therapy remains difficult to achieve, even as advances in medical science have improved diagnosis and management. Numerous current treatments have drawbacks, including low medication absorption, insufficient liver tissue targeting, and unfavorable side effects. These difficulties highlight the need for creative therapeutic approaches.

With benefits, such as improved drug absorption, site-specific distribution, and reduced systemic toxicity, nanocarrier-based drug delivery systems have become a viable alternative. These technologies offer the opportunity to improve treatment outcomes for individuals with fatty liver disease by addressing the drawbacks of traditional approaches.

This book offers a thorough analysis of nanocarrier technologies and their potential for treating fatty liver disease. It provides readers with a comprehensive understanding of the potential impact of nanotechnology in this field by examining key concepts, therapeutic applications, and current research. The material bridges the gap between theoretical understanding and real-world application, covering everything from fundamental scientific concepts to the latest developments.

The book is intended as a useful resource for medical researchers, healthcare practitioners, and those in the pharmaceutical sector. It supports upcoming research projects in the field of drug delivery systems, fosters multidisciplinary collaboration, and stimulates new ideas.

We express our heartfelt gratitude to all of the writers and specialists who gave their time and expertise to this collection. In addition to offering clarification and direction, we hope that our work encourages further research and development in the management of fatty liver disease.

Anjali Sharma
Department of Pharmaceutics
Guru Gobind Singh College of Pharmacy
Yamunanagar, Haryana
India

Devkant Sharma
Department of Pharmaceutics
Ch. DeviLal College of Pharmacy
Jagadhri, Haryana
India

Ajmer Singh Grewal
Department of Pharmaceutical Chemistry
Guru Gobind Singh College of Pharmacy
Yamunanagar, Haryana
India

Geeta Deswal
Department of Pharmacognosy
Guru Gobind Singh College of Pharmacy
Yamunanagar, Haryana
India

&

Ganga Reddy Velma
Department of Pharmacology & Toxicology
R. Ken Coit College of Pharmacy
University of Arizona, Tucson
Arizona, United States