Authors: Nura Brimo, Emir Baki Denkbas, Beyzanur Cakar

Nanomaterials in Glioblastoma Research, Diagnosis and Therapy

eBook: US $39 Special Offer (PDF + Printed Copy): US $63
Printed Copy: US $43
Library License: US $156
ISBN: 978-981-5324-19-8 (Print)
ISBN: 978-981-5324-18-1 (Online)
Year of Publication: 2025
DOI: 10.2174/97898153241811250101

Introduction

Nanomaterials in Glioblastoma Research, Diagnosis, and Therapy offers a comprehensive exploration of how nanotechnology is revolutionizing the fight against glioblastoma (GBM), one of the deadliest and most treatment-resistant brain cancers. The book covers the molecular and epigenetic mechanisms underlying GBM, laying the foundation for innovative strategies in diagnosis and therapy. It highlights cutting-edge advances, including nanomaterial-based biosensors for early diagnosis, biomaterials to enhance immunotherapy, and novel therapeutic approaches like gold nanoparticles, cold plasma, and combinational nanomedicine. The book also addresses critical challenges such as overcoming the blood-brain barrier through oral delivery nanostructures and provides future perspectives on clinical applications.


Key Features:

  • - Insights into GBM genetics, epigenetics, and molecular pathways.
  • - Applications of nanomaterials in drug delivery, imaging, and immunotherapy.
  • - Detailed coverage of advanced diagnostics and therapeutic strategies.
  • - Future directions and challenges in nanotechnology-based GBM treatment.


Readership

This essential resource is ideal for researchers, oncologists, nanotechnology specialists, and graduate students seeking innovative solutions to advance GBM diagnosis and therapy.

Preface

Welcome to "Nanomaterials in Glioblastoma Research, Diagnosis and Therapy"! In this groundbreaking book, we explore the unprecedented potential of nanotechnology in revolutionizing the field of glioblastoma research, diagnosis, and therapy. Glioblastoma, the most aggressive form of brain cancer, has posed significant challenges to clinicians, researchers, and patients alike for decades. Current treatment options often fall short of providing effective and long-lasting solutions. However, with the advent of nanotechnology, a new era of possibilities has dawned upon us.

The integration of nanomaterials into glioblastoma research has allowed for remarkable advancements in detection, imaging, drug delivery, and therapy. Nanotechnology offers precise control over the targeted delivery of therapeutics, enabling the enhancement of treatment efficacy while minimizing side effects. Moreover, nanomaterials possess unique physicochemical properties that can be harnessed for improved diagnostics and monitoring of glioblastoma progression. This book brings together leading experts in the field, who have made significant contributions to the development and application of nanomaterials in glioblastoma research and therapy. Each chapter explores the latest discoveries, methodologies, and breakthroughs, providing a comprehensive overview of the current state of the art in nanotechnology for glioblastoma.

We begin by delving into the fundamental principles of nanomaterials, their synthesis, and characterization techniques. Subsequently, we delve into the utilization of nanomaterials for imaging glioblastoma, from traditional imaging modalities to cutting-edge molecular imaging and theranostics approaches. The subsequent sections delve into the innovative applications of nanomaterials in targeted drug delivery, gene therapy, immunotherapy, and hyperthermia. Each chapter uncovers the immense potential of nanotechnology in enhancing the efficacy of therapeutic interventions while minimizing the adverse effects on healthy brain tissue.

Finally, we explore emerging trends and future directions in nanomaterials research, highlighting the ongoing efforts to translate these advancements from the laboratory bench to the clinical setting. We also address the challenges and ethical considerations surrounding the use of nanomaterials in glioblastoma research and therapy. "Nanomaterials in Glioblastoma Research, Diagnosis and Therapy" aims to serve as a comprehensive resource for scientists, clinicians, and students interested in the intersection of nanotechnology and glioblastoma. We hope that the knowledge shared within these pages will spark curiosity, drive innovation, and ultimately contribute to the development of effective treatments for this devastating disease. We would like to express our gratitude to the contributing authors for their invaluable insights and expertise, as well as the diligent efforts of the editorial team in bringing this book to fruition. May this collective endeavor pave the way toward a brighter future for glioblastoma patients through the power of nanomaterials.

Nura Brimo

Emir Baki Denkbas

Beyzanur Cakar
Department of Biomedical Engineering
Başkent University, Ankara
Turkey