Editors: Tapan Kumar Mukherjee, Parth Malik, Ruma Rani

Glycosylation and Glycation in Health and Diseases

eBook: US $79 Special Offer (PDF + Printed Copy): US $146
Printed Copy: US $106
Library License: US $316
ISBN: 978-981-5322-53-8 (Print)
ISBN: 978-981-5322-52-1 (Online)
Year of Publication: 2025
DOI: 10.2174/97898153225211250101

Introduction

Glycosylation and Glycation in Health and Diseases provides a comprehensive exploration of the essential biochemical processes, their implications in physiology, and their role in disease progression.

This book is divided into two key sections: the first focuses on glycosylation, an enzymatic process essential for cellular function, while the second covers glycation, a nonenzymatic reaction linked to aging and chronic diseases. It covers congenital glycosylation disorders, the biology of advanced glycation end products (AGEs), and the critical role of the receptor for AGEs (RAGE) in inflammatory, neurological, cardiovascular, and cancer-related conditions.

A valuable resource for students, researchers, and industry professionals, this book highlights the significance of glycobiology in drug discovery, diagnostics, and therapeutic innovations.

Key Features:

  • - Covers fundamental and advanced concepts of glycosylation and glycation.
  • - Discusses the role of glycans in cellular function and disease pathology.
  • - Explores AGE-RAGE interactions in cardiovascular, pulmonary, and neurological disorders.
  • - Highlights applications in biopharmaceuticals, diagnostics, and vaccine development.

Readership

Essential reading for students, researchers, and professionals in life sciences, biotechnology, and pharmaceutical fields.

Preface

- Pp. i-ii (2)
Tapan Kumar Mukherjee*, Parth Malik, Ruma Rani
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List of Contributors

- Pp. ii-iii (1)

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The Basic Concept of Glycosylation

- Pp. 1-39 (39)
Parth Malik, Ruma Rani, Tapan Kumar Mukherjee*

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Vital Functions of Glycans in the Biological Systems

- Pp. 40-83 (44)
Ruma Rani, Parth Malik, Raj Singh, Raman Kumar, Vishal Haribhai Patel, Tapan Kumar Mukherjee*

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Understanding Congenital Glycosylation Disorders

- Pp. 84-119 (36)
Himel Mondal, Shaikat Mondal, Rajeev K. Singla*

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The Biology of Advanced Glycation End Products

- Pp. 120-189 (70)
Parth Malik, Ruma Rani, Tapan Kumar Mukherjee*

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Receptor for Advanced Glycation End Products in Health and Physiology

- Pp. 190-239 (50)
Ruma Rani, Parth Malik, Tapan Kumar Mukherjee*

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Receptor for Advanced Glycation End Products as a Mediator of Inflammation and Oxidative Stress

- Pp. 240-285 (46)
Ruma Rani, Parth Malik, Tapan Kumar Mukherjee*

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Receptor for Advanced Glycation End Products in Pulmonary Diseases

- Pp. 286-325 (40)
Parth Malik, Ruma Rani, Tapan Kumar Mukherjee*

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Receptor for Advanced Glycation End Products in Cardiovascular and Diabetic Complication(s)

- Pp. 326-368 (43)
Ruma Rani, Parth Malik, Tapan Kumar Mukherjee*

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Receptor for Advanced Glycation End Products in Various Types of Cancers

- Pp. 369-407 (39)
Ruma Rani, Parth Malik, Tapan Kumar Mukherjee*

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Receptor for Advanced Glycation End Products in Neuronal Pathophysiology

- Pp. 408-459 (52)
Parth Malik, Ruma Rani, Tapan Kumar , Mukherjee*

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Subject Index

- Pp. 460-466 (7)
Tapan Kumar Mukherjee, Parth Malik, Ruma Rani
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