Editors: Hafize Uzun, Seyma Dumur

Metabolic Syndrome: A Comprehensive Update with New Insights

eBook: US $59 Special Offer (PDF + Printed Copy): US $128
Printed Copy: US $98
Library License: US $236
ISBN: 978-981-5322-14-9 (Print)
ISBN: 978-981-5322-13-2 (Online)
Year of Publication: 2025
DOI: 10.2174/97898153221321250101

Introduction

The book focuses on a new interdisciplinary understanding of the metabolic syndrome (MetS) for better health maintenance. It provides an updated understanding of the underlying principles, possible targets, implementation approaches and the effectiveness of various avoidance strategies in MetS. The chapters cover a wide range of topics, including major advances in general aspects of metabolic syndrome, functional changes, new diagnostic methods, genotype-phenotype associations, the effect of exercise and multitarget pharmacotherapeutic strategies for MetS and perspectives on personalized medicine. It also discusses epigenetic mechanisms underlying MetS-related processes and epigenetic strategies to prevent related diseases. The book also presents summarized information about the associated factors and mechanisms linking cancer and MetS and to identify potential targets for the treatment of these patients. A better understanding of the various linkages will provide greater insight into the management of cancer patients by preventing MetS and related alterations.

Key Features:

  • - Comprehensive information focused on the biological factors and physiological changes associated with metabolic syndrome
  • - Updates on metabolic syndrome diagnosis and management
  • - Summarized information on clinical implications for cancer therapy
  • - Thoroughly referenced chapters with summaries and discussions for quick understanding

The book is an informative resource for interdisciplinary scientists and researchers in life sciences and medicine. Furthermore, it, including the insulin-like growth factor (IGF-1) pathway, estrogen signaling, visceral adiposity, hyperinsulinemia, hyperglycemia, aromatase activity, adipokinase production, angiogenesis, oxidative stress, DNA damage and pro-inflammatory cytokines, and their clinical implications in cancer therapy.

Readership

General readers, microbiology and biotechnology enthusiasts, science students and industrial trainees.

Foreword

Metabolic syndrome is an intricate condition characterized by a set of risk factors, including hyperglycemia, insulin resistance, hypertension, and obesity, which significantly elevate the risk of cardiovascular disease, stroke, and type 2 diabetes. Its growing prevalence worldwide poses a significant challenge to public health, necessitating a thorough understanding and innovative strategies for management. This book offers an in-depth exploration of metabolic syndrome, shielding a range of issues from functional changes and novel diagnostic methods to the interplay between metabolic syndrome and other health conditions like cancer, gastrointestinal disorders, and COVID-19. This complete text, featuring chapters on cutting-edge research and practical diagnosing and management strategies, is a valuable resource for healthcare professionals, researchers, and policymakers dedicated to addressing the multifaceted challenges of this syndrome.

Era Gorica
Department of Cardiology
Center for Translational and Experimental Cardiology (CTEC)
University Hospital Zürich, Wagistrasse 12, 8952 Schlieren
Switzerland