Metabolic Syndrome: A Comprehensive Update with New Insights

The book focuses on a new interdisciplinary understanding of the metabolic syndrome (MetS) for better health maintenance. It provides an updated understanding of the underlying principles, possible targets, implementation approaches and the effectiveness of various avoidance strategies in MetS. The chapters cover a wide range of topics, including major advances in general aspects of metabolic syndrome, functional changes, new diagnostic methods, genotype-phenotype associations, the effect of exercise and multitarget pharmacotherapeutic strategies for MetS and perspectives on personalized medicine. It also discusses epigenetic mechanisms underlying MetS-related processes and epigenetic strategies to prevent related diseases. The book also presents summarized information about the associated factors and mechanisms linking cancer and MetS and to identify potential targets for the treatment of these patients. A better understanding of the various linkages will provide greater insight into the management of cancer patients by preventing MetS and related alterations.

Key Features:

- Comprehensive information focused on the biological factors and physiological changes associated with metabolic syndrome
- Updates on metabolic syndrome diagnosis and management
- Summarized information on clinical implications for cancer therapy
- Thoroughly referenced chapters with summaries and discussions for quick understanding

The book is an informative resource for interdisciplinary scientists and researchers in life sciences and medicine. Furthermore, it, including the insulin-like growth factor (IGF-1) pathway, estrogen signaling, visceral adiposity, hyperinsulinemia, hyperglycemia, aromatase activity, adipokinase production, angiogenesis, oxidative stress, DNA damage and pro-inflammatory cytokines, and their clinical implications in cancer therapy.

Readership

General readers, microbiology and biotechnology enthusiasts, science students and industrial trainees.

Editor(s):

Hafize Uzun
Department of Medical Biochemistry
Istanbul Atlas University
Faculty of Medicine
Istanbul
Turkey

Seyma Dumur
Department of Medical Biochemistry
Istanbul Atlas University
Faculty of Medicine
Istanbul
Turkey

Contributor(s):

Abdulhalim Senyigit
Department of Internal Medicine
Faculty of Medicine, Istanbul Atlas University
Istanbul
Turkey

Ahmed Saber Shams
Human Anatomy and Embryology Department
Faculty of Medicine
Suez Canal University
Ismailia
Egypt

Asli Kutlu
Department of Molecular Biology and Genetics
Faculty of Engineering and Natural Sciences, Istinye University
Istanbul
Turkiye

Asmaa Seddek
Department of Medical Physiology
Faculty of Medicine, Suez Canal University
Ismailia
Egypt

Berrin Papila
Istanbul University-Cerrahpasa
Cerrahpasa Medical Faculty
Istanbul
Turkey

Dahlia Badran
Medical Biochemistry & Molecular Biology department
Medicine faculty, Suez Canal University
Egypt
/
Medical Biochemistry & Molecular Biology department
Medicine faculty, Badr University in Cairo
Egypt

Dina A Ali
Clinical pharmacology Department
Faculty of Medicine, Suez Canal University
Ismailia, 41522
Egypt

Demet Aygun
Department of Neurology
Medicine Faculty, Istanbul Atlas University
Istanbul
Turkey

Derya Aydın Sivri
Department of Obstetrics and Gynecology
Faculty of Medicine, Istanbul Atlas University
İstanbul
Turkey

Esra Bihter Gürler
Department of Physiology
Faculty of Dentistry, İstanbul Galata University
İstanbul
Turkey

Eman Mamdouh Kolieb
Physiology Department
Faculty of Medicine, Suez Canal University
Ismailia, 41522
Egypt

Esma Altinoglu
Department of Internal Medicine
School of Medicine, Bahcesehir University
Istanbul
Turkey

Fatma S. Samman
Department of Clinical Pharmacology
Faculty of Medicine, Suez Canal University
41522 Ismailia
Egypt

Fatma Köksal Çakırlar
stanbul University-Cerrahpasa
Cerrahpasa medicine Faculty
Istanbul
Turkey

Hülya Çevik ARAS
Department of Oral Medicine and Pathology
University of Gothenburg
Göteborg
Sweden

Hurriyet Cetinok
Istanbul Atlas University
Istanbul
Turkey

Halit Eren Taşkın
Department of General Surgery
Istanbul University-Cerrahpasa Cerrahpasa Medical Faculty
34098, Istanbul, Fatih
Turkey

Hafize Uzun
Department of Medical Biochemistry
Faculty of Medicine, Istanbul Atlas University
Istanbul
Turkey

Iskender Ekinci
Department of Internal Medicine
Faculty of Medicine, Bezmialem Vakıf University
Istanbul
Turkey

Marwa Mohamed Hosny
Medical Biochemistry and Molecular Biology Department
Faculty of Medicine
Suez Canal University
Ismailia
Egypt
/
Oncology Diagnostic Unit
Faculty of Medicine
Suez Canal University
Ismailia
Egypt

Mohamed Salah Rashwan
Department of Otolaryngology
Faculty of Medicine, Suez Canal University
Ismailia
Egypt
/
Department of Otolaryngology
Queen’s Hospital, Barking, Havering and Redbridge University Hospitals NHS Trust
Romford
UK

Nagihan Bostanci
Department of Dental Medicine
Karolinska Institutet
Stockholm
Sweden

Nora Hosny
Medical Biochemistry and Molecular Biology Department
Faculty of Medicine
Suez Canal University
Ismailia
Egypt

Noura Ramadan Abdel-hamid
Department of Histology and Cell Biology
Faculty of Medicine, Suez Canal University
Ismailia, 41522
Egypt

Naile Misirlioglu
Department of Biochemistry
Gaziosmanpaşa Training and Research Hospital, University of Health Sciences
Istanbul
Turkey

Neval Elgörmüş
Department of Microbiology
Faculty of Medicine, Istanbul Atlas University
Istanbul
Turkey

Omer Okuyan
Istanbul Atlas University
Istanbul
Turkey

Pelin Uysal
Department of Pulmonary Medicine
Faculty of Medicine, Istanbul Atlas University
Istanbul
Turkey

Ravindri Jayasinghe
Department of Surgery
Faculty of Medicine, University of Colombo
Colombo
Sri Lanka

Sinem Firtina
Department of Medical Genetics
Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa
Istanbul
Turkiye

Shimaa Mohammad Yousof
Department of Medical Physiology
Faculty of Medicine in Rabigh, King Abdulaziz University
Rabigh
Saudi Arabia

Samah M. Elaidy
Department of Clinical Pharmacology
Faculty of Medicine, Suez Canal University
41522 Ismailia
Egypt

Samar Imbaby
Department of Clinical Pharmacology
Faculty of Medicine, Suez Canal University
41522 Ismailia
Egypt

Seyma Dumur
Department of Medical Biochemistry
Faculty of Medicine, Istanbul Atlas University
Istanbul
Turkey

Sanjeewa Seneviratne
Department of Surgery
Faculty of Medicine, University of Colombo
Colombo
Sri Lanka

Umesh Jayarajah
Department of Surgery
Faculty of Medicine, University of Colombo
Colombo
Sri Lanka

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