Editors: Divya Bajpai Tripathy, Anjali Gupta, Arvind Kumar Jain, Pooja Agarwal

Applications of Nanoparticles in Drug Delivery and Therapeutics

eBook: US $59 Special Offer (PDF + Printed Copy): US $107
Printed Copy: US $77
Library License: US $236
ISBN: 978-981-5256-51-2 (Print)
ISBN: 978-981-5256-50-5 (Online)
Year of Publication: 2024
DOI: 10.2174/97898152565051240101

Introduction

Applications of Nanoparticles in Drug Delivery and Therapeutics is an authoritative review on nanoparticle-based drug delivery systems. This comprehensive volume focuses on the transformative role of nanoparticles in enhancing drug delivery systems and advancing therapeutic applications. By bridging the gap between laboratory research and clinical practice, this book offers a thorough exploration of how nanotechnology is revolutionizing the pharmaceutical industry.

The book is structured into well-organized chapters, each dedicated to a specific aspect of nanoparticle-based drug delivery and therapy. Initial chapters provide a foundational understanding of nanoparticle synthesis, characterization, and functionalization. Subsequent sections cover various types of nanoparticles, including liposomes, dendrimers, and polymeric nanoparticles, highlighting their unique properties and applications. The latter chapters delve into case studies and clinical trials, showcasing real-world applications and the therapeutic potential of nanoparticle technologies in treating diseases like cancer, cardiovascular disorders, and neurodegenerative diseases.

Key features of this book include detailed discussions on the design and optimization of nanoparticles for targeted drug delivery, insights into the regulatory and safety aspects of nanomedicine, and comprehensive reviews of current and emerging therapeutic applications. The book also offers practical guidance on the challenges and future directions in the field, making it an invaluable reference for researchers and practitioners alike.

Chapters 1 and 2 are based on the introduction of nanomaterials used as drug delivery systems, their manufacturing approaches and applications. Chapters 3 and 4 emphasize on the use of nanoparticles in medical diagnostics and in intervention devices. Chapters 5 and 6 illustrate the use of lipids-based nanoparticles in medical imaging and drug delivery. Chapter 7 specifically discusses amino acid functionalized inorganic nanoparticles in diagnostics. Chapter 8 is focused on the special class of nanoparticles “hybrid nanocomposites”. Chapters 9 and 10 covers the applications of silica and fullerene nanomaterials in anticancer drug delivery.

The book is intended as a resource for pharmaceutical scientists, biomedical researchers, and healthcare professionals keen on the latest advancements in drug delivery systems. It also serves as essential reading for graduate students and academics in pharmacology and medical courses that require learning about modern drug delivery systems.

Readership

Students, pharmaceutical scientists and healthcare professionals.

Preface

In the rapidly evolving landscape of modern medicine, the convergence of nanotechnology and pharmaceutical sciences has given rise to a revolutionary paradigm in drug delivery and therapeutic interventions. The utilization of nanoparticles, with their unique physicochemical properties and versatile applications, has opened up new avenues for addressing complex healthcare challenges. This book, "Applications of Nanoparticles in Drug Delivery and Therapeutics", endeavors to provide a comprehensive exploration of the diverse and dynamic field of nanotherapeutics.

The chapters presented within this volume offer an in-depth analysis of how nanoparticles are being harnessed to revolutionize various aspects of healthcare, ranging from antibacterial and antiviral interventions to targeted cancer treatments. Each chapter delves into a specific application of nanotechnology, highlighting the innovative strategies, methodologies, and breakthroughs that are propelling the field forward.

In Chapter 1, "Nanotherapeutics as Antibacterial and Antiviral Agents: Approach Beyond Antibiotics", we venture beyond conventional antibiotics, showcasing how nanoparticles are redefining the fight against microbial threats.

Chapter 2, "Novel Approaches for the Synthesis of Nanomaterials for Nanodevices in Medical Diagnostics", explores the cutting-edge techniques employed in the creation of nanomaterials tailored for diagnostic purposes, underscoring their potential to revolutionize medical diagnostics.

Chapter 3, "Application of Nanotechnology in Nutraceuticals and Functional Foods", uncovers the intersection of nanotechnology and nutrition, revealing how nanoparticles are enhancing the bioavailability and therapeutic potential of nutraceuticals. The concept of enzyme-responsive nanoparticles is the focus of Chapter 4, elucidating their pivotal role in intelligent drug delivery systems that respond to specific biochemical cues.

In Chapter 5, "Application of Nanotherapeutics in Cancer Treatment", the spotlight shifts to oncology, where nanoparticles are emerging as potent tools for precise cancer targeting and therapy.

Chapter 6, "Anti-HIV Nanotherapeutics and their Challenges in the Future", takes on the formidable challenge of combatting HIV, exploring the promises and hurdles associated with nanotechnology-based HIV interventions.

The ongoing battle against Alzheimer's Disease takes center stage in Chapter 7, "Current Perspectives of Nanotherapeutics for the Treatment of Alzheimer’s Disease", revealing how nanoparticles may offer novel avenues for therapeutic intervention.

Chapter 8, "Nanotherapeutics in Skin Therapy", turns attention to dermatology, showcasing the transformative potential of nanoparticles in skincare and dermatological treatments.

The socioeconomic dimensions of nanomaterials find their place in Chapter 9, "Economical and Environmental Aspects of Nanomaterials: Journey of Sustainable and Cost-Effective Nanoparticles from Lab to Industry", where we explore the transition of nanotherapeutics from research laboratories to industrial applications, considering both economic viability and environmental sustainability.

Finally, Chapter 10, "Patent Landscape of Nanotechnology in Healthcare", offers a comprehensive overview of the patent landscape surrounding nanotechnology applications in healthcare, shedding light on the innovations and intellectual property shaping the field.

Collectively, these chapters endeavor to provide a panoramic view of the multifaceted landscape of nanoparticle applications in drug delivery and therapeutics. They celebrate the strides made thus far while also acknowledging the challenges that lie ahead. As we embark on this journey through the realm of nanotherapeutics, we invite readers to explore the potential of these minuscule agents to effect monumental changes in the way we approach and conquer complex medical challenges.

Divya Bajpai Tripathy
Anjali Gupta
Arvind Kumar Jain

&

Pooja Agarwal

Department of Chemistry
School of Basic and Applied Sciences
Galgotias University, Greater Noida-201312
India