Editors: Anuradha Mishra, Preeti Bajpai, Tarique Mahmood Ansari

Advances in Diagnostics and Immunotherapeutics for Neurodegenerative Diseases

eBook: US $59 Special Offer (PDF + Printed Copy): US $101
Printed Copy: US $71
Library License: US $236
ISBN: 978-981-5238-76-1 (Print)
ISBN: 978-981-5238-75-4 (Online)
Year of Publication: 2024
DOI: 10.2174/97898152387541240101

Introduction

Advances in Diagnostics and Immunotherapeutics for Neurodegenerative Diseases delves into the intricate mechanisms underlying neurodegenerative disorders and highlights cutting-edge diagnostic methods and innovative immunotherapeutic strategies. This comprehensive book addresses several key themes crucial to understanding and combating these debilitating conditions with an updated understanding of neurodegenerative disorders and a review of the latest advancements in diagnostic and treatment strategies.

Key Themes

  • - Neuroinflammation: examines the complex molecular pathways involved in neuroinflammatory responses and their impact on disease dynamics.
  • - Gut-Brain Axis: A thorough discussion on the relationship between the gut microbiome and neurodegenerative processes is presented.
  • - Advanced Diagnostics: A state-of-the-art review of diagnostic techniques provides updates on advanced neuroimaging modalities, cerebrospinal fluid biomarker analysis, and genetic testing.
  • - Epigenetic Regulation of Microglia: Covers the emerging field of epigenetic modifications and their role in modulating microglial activation and function.
  • -Immunotherapeutics: Learn about the potential of monoclonal antibodies, immune modulators, and repurposed drug therapies in slowing disease progression and improving patient outcomes.

This book serves as a valuable resource for researchers, clinicians, and students in the fields of molecular biology, neuroimmunology, and clinical neurology.

Readership

Researchers, clinicians, and students in the fields of molecular biology, neuroimmunology, and clinical neurology.

Foreword

- Pp. i
Rakesh Kumar Dixit
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Preface

- Pp. ii-iii (2)
Anuradha Mishra, Preeti Bajpai, Tarique Mahmood Ansari
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Introduction

- Pp. iv

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List of Contributors

- Pp. v-vi (2)

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A Systematic Review of Neurodegenerative Diseases: Etiology, Clinical Symptoms, Pathogenesis, and Future Developments

- Pp. 1-16 (16)
Satya Prakash Singh*, Deepti Dwivedi, Rabiya Ahsan, Ankur Srivastava, Ajay Kumar Shukla

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Neuro-inflammatory Responses in Alzheimer’s v/s Parkinson’s Diseases

- Pp. 17-31 (15)
Amrutha K., Sarika Singh*

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Immunopathogenesis of Alzheimer’s disease, Parkinson’s Disease, and other Neurodegenerative Diseases

- Pp. 32-64 (33)
Sunil Kumar, Ajay Kumar Shukla, Vimal Kumar Yadav, Ankur Srivastava, Deepti Dwivedi, Satya Prakash Singh*

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Immunobiology and Immunotherapies in Huntington's Disease

- Pp. 65-87 (23)
Arttatrana Pal*, Golden Kumari, Sonu Kumar

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Introduction to Gut Microbiota and their Effects on Various Brain Disorders

- Pp. 88-103 (16)
Afreen Usmani*, Anuradha Mishra

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Interplay Between Gut-microbiota and Neurodegeneration

- Pp. 104-145 (42)
Sumel Ashique*, Radheshyam Pal, Shubneesh Kumar, Bharti Verma, Nitish Kumar, Ivan Kahwa, Arshad Farid, Neeraj Mishra*, Prashant Kumar, Farzad Taghizadeh-Hesary

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Epigenetic Regulation of Microglia: Plausible Mechanism and Interventional Approaches in Neurodegeneration

- Pp. 146-161 (16)
Sameen Shafi, Hafizur Rahman Khan, Preeti Bajpai*

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Epigenetics as Diagnostic and Therapeutic Tool in Neurodegenerative Disorders

- Pp. 162-176 (15)
Rufaida Wasim*, Tarique Mahmood, Farogh Ahsan, Aditya Singh, Asad Ahmad

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Current Therapeutic Options and Repurposed Drugs for Neurodegeneration

- Pp. 177-219 (43)
Suneela Dhaneshwar*, Mohammad Aadil Bhat, Anuradha Singh, Supriya Roy

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Subject Index

- Pp. 220-225 (6)
Anuradha Mishra, Preeti Bajpai, Tarique Mahmood Ansari
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