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Bioceramics: Status in Tissue Engineering and Regenerative Medicine (Part 1)

Editors: Saeid Kargozar, Francesco Baino

Bioceramics: Status in Tissue Engineering and Regenerative Medicine (Part 1)

ISBN: 978-981-5238-40-2
eISBN: 978-981-5238-39-6 (Online)

Introduction

Bioceramics: Status in Tissue Engineering and Regenerative Medicine (Part 1) provides an in-depth look into the recent advancements in biocompatible ceramics, glasses, and composites for tissue engineering and regenerative medicine. It explores topics ranging from the structure and processing of bioactive glasses to the applications of bioinert and bioresorbable ceramics in medical treatments. The book discusses key aspects of bioceramics, including their therapeutic potential in soft tissue healing and cancer therapy, along with challenges and opportunities for future research. Researchers, bioengineers, and professionals in biomedical sciences will find this volume an essential resource for understanding both the fundamentals and applications of bioceramics.

Key Features:

  1. - Comprehensive coverage of bioceramics, bioactive glasses, and composites, including their manufacturing techniques.
  2. - State-of-the-art insights into bioceramics and glass-ceramics in tissue engineering and regenerative medicine.
  3. - Focus on preclinical assessment, clinical applications, challenges, and future perspectives.

This monograph is intended as a resource for the broad research community involved in materials and device testing for batteries at academic and industrial levels. It also serves as a reference for engineering students required to learn advanced characterization techniques for developing rechargeable battery technology.

Readership

Academia, Ph.D. or Postgraduate Researchers, and Industry Professionals.

Foreword

The use of bioceramics for tissue engineering and regenerative medicine extends over two centuries. Dorozhkin provided a detailed review of the history of bioceramics [1]. He noted that Johan Gottlieb Gahn and Carl Wilhelm Scheele first described the presence of calcium and phosphorus in bone in the second half of the eighteenth century [1, 2]. The first use of bioceramics in medicine occurred in the late nineteenth century when Junius E. Cravens distributed a calcium orthophosphate powder called “Lacto-Phosphate of Lime” for capping the dental pulp during dental restorations [1, 3, 4]. Larry Hench's discovery in 1969 that a sodium-calcium-phosphorous-–silicate glass possesses bone bonding functionality gave rise to the clinical use of “bioactive glass” materials for bone repair [5, 6]. The term “bioceramics” was first used shortly thereafter in 1971 [7]. The bioceramics field is now truly global in nature and includes research, pre-clinical, and clinical activities involving various types of bioactive and bioinert inorganic materials.

This volume by Saeid Kargozar, a research fellow in the Department of Radiation Oncology, Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, and Francesco Baino, an associate professor in the Department of Applied Science and Technology at the Politecnico di Torino, provides a comprehensive overview of the use of bioceramics for tissue engineering and regenerative medicine. The first part of the book (Part 1) focuses on the fundamentals of biocompatible ceramics, bioactive glasses and composites, and collects 10 chapters. In Chapter 1, Kargozar and Baino provide a description of the status of bioceramics in tissue engineering and regenerative medicine. Chapter 2, by Moghanian et al., provides an introduction to biocompatible glasses, ceramics, and glass ceramics. Batool et al. consider recent advances in bioactive glasses and glass ceramics in Chapter 3. Chapter 4, by Bahati et al., describes the structure, properties, and processing of bioactive glasses. Kargozar et al. focus on the biocompatibility of bioactive glasses in Chapter 5. In Chapter 6, Moghanian and Nasiripour describe the use of bioinert ceramics for biomedical applications. Moghanian et al. review the processing and properties of bioresorbable ceramics in Chapter 7. Dorozhkin reviews the use of calcium orthophosphates in tissue engineering in Chapter 8. In Chapter 9, Hosseini et al. consider the use of carbon nanostructures for tissue engineering and cancer therapy. Benedini and Messina describe advances in polymer/ceramic composites for bone tissue engineering in Chapter 10. The second part of the book (Part 2) will be addressed to the applications of the bioceramic materials discussed in the present volume.

In this volume, Professors Kargozar and Baino as well as the chapter contributors have provided the bioceramics community with a comprehensive consideration of the bioceramics field. I anticipate that their volume will be beneficial to students as well as researchers in academia, government, and industry as they continue efforts to improve our understanding of the use of bioceramic materials for tissue engineering and regenerative medicine applications.

Prof. Roger Narayan
Joint Department of Biomedical Engineering
North Carolina and North Carolina State University
Raleigh, USA
REFERENCES 1  Dorozhkin S.V. A detailed history of calcium orthophosphates from 1770s till 1950. Mater. Sci. Eng. C 2013 33 6 3085 3110 10.1016/j.msec.2013.04.002 23706189 2  Dorozhkin S.V. A history of calcium orthophosphates (CaPO 4 ) and their biomedical applications. Morphologie 2017 101 334 143 153 10.1016/j.morpho.2017.05.001 28595833 3  Dorozhkin SV Calcium orthophosphates as a dental regenerative material. 2019 10.1016/B978-0-08-102476-8.00016-5 4  Cravens J.E. Lacto-phosphate of lime; Pathology and treatment of exposed dental pulps and sensitive dentine. Dent. Cosmos 1876 18 463 469 5  Hench L.L. The story of Bioglass®. J. Mater. Sci. Mater. Med. 2006 17 11 967 978 10.1007/s10856-006-0432-z 17122907 6  Hench L.L. Splinter R.J. Allen W.C. Greenlee T.K. Bonding mechanisms at the interface of ceramic prosthetic materials. J. Biomed. Mater. Res. 1971 5 6 117 141 10.1002/jbm.820050611 7  Blakeslee K.C. Condrate R.A. Sr Vibrational spectra of hydrothermally prepared hydroxyapatites. J. Am. Ceram. Soc. 1971 54 11 559 563 10.1111/j.1151-2916.1971.tb12207.x