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Heterocyclic Anti-Inflammatory Agents: A Guide for Medicinal Chemists

Editors: Anjaneyulu Bendi, M.P. Kaushik, Neera Raghav

Heterocyclic Anti-Inflammatory Agents: A Guide for Medicinal Chemists

ISBN: 978-981-5223-47-7
eISBN: 978-981-5223-46-0 (Online)

Introduction

This book summarizes the cutting-edge experimental research on heterocyclic compounds used as anti-inflammatory agents in ten chapters. Each chapter is authored by experts in medicinal chemistry and is supplemented with scientific references for advanced reading.

The book covers several types of heterocyclic compounds and their derivatives including

  • - pyrimidine and pyrimidinone derivatives
  • - 1,2,3, and 1,2,4 triazoles
  • - imidazole and benzimidazole derivatives
  • - oxazole, oxadiazole, isoxazoline, and oxazoline derivatives
  • - thiazole and thiazolidinone derivatives
  • - pyrazole and pyrazoline
  • - Carbazoles and their derivatives
  • - azipines, quinolines, and coumarins

This is a timely reference for medicinal chemists interested in developing new heterocycles for anti-inflammatory drugs. Contributors have discussed the effects of these compounds on different types of inflammation and their evolution in drug development as therapeutic agents to give a wider perspective to readers.

Readership:

Students, professionals, and researchers in medicinal chemistry, pharmaceutical chemistry, and drug development.

Foreword

It is my pleasure to write the foreword for the book entitled "Heterocyclic Anti-Inflammatory Agents: A Guide for Medicinal Chemists" edited by Anjaneyulu Bendi, M. P. Kaushik, and Neera Raghav . All the editors are well-known researchers working in different areas of organic and medicinal chemistry.

A large number of anti-inflammatory drugs are currently being used. However, many of these compounds are found to be highly unsafe for long-term use due to the associated toxicity. It has been established that the incorporation of heterocyclic moiety provides a useful tool for the modification of polarity, solubility, lipophilicity and hydrogen bonding capacity of such compounds. Going deeper into the book, the significance of heterocyclic compounds in the development of anti-inflammatory agents becomes apparent.

This book will be helpful for both, beginners and experimental researchers, working in the interdisciplinary areas involving chemistry, medicinal chemistry and pharmaceutical chemistry. It will also benefit the students who are pursuing a course involving the role of heterocyclic compounds in the development of medicinal agents in general, and of anti-inflammatory drugs in particular.

I hope that the book will be received well by the scientific community.

S. P. Singh
Kurukshetra University
Kurukshetra-136119
Haryana, India