Editors: Mohd Fauzi Mh Busra, Daniel Law Jia Xian, Yogeswaran Lokanathan, Ruszymah Haji Idrus

Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside (Part 2)

eBook: US $59 Special Offer (PDF + Printed Copy): US $101
Printed Copy: US $71
Library License: US $236
ISBN: 978-981-5179-34-7 (Print)
ISBN: 978-981-5179-33-0 (Online)
Year of Publication: 2024
DOI: 10.2174/97898151793301240101

Introduction

Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside explores the use of bio-based materials for the regeneration of tissues and organs. The book presents an edited collection of 28 topics in 2 parts focused on the translation of these materials from laboratory research (the bench) to practical applications in clinical settings (the bedside). Chapter authors highlight the significance of bio-based materials, such as hydrogels, scaffolds, and nanoparticles, in promoting tissue regeneration and wound healing.

Topics included in the book include:

  • - the properties of bio-based materials, including biocompatibility, biodegradability, and the ability to mimic the native extracellular matrix.
  • - fabrication techniques and approaches for functional bio-based material design with desired characteristics like mechanical strength and porosity to promote cellular attachment, proliferation, and differentiation.
  • - the incorporation of bioactive molecules, such as growth factors, into bio-based materials to enhance their regenerative potential.
  • - strategies for the controlled release of molecules to create a favorable microenvironment for tissue regeneration.
  • - the challenges and considerations involved in scaling up the production of bio-based materials, ensuring their safety and efficacy, and obtaining regulatory approval for clinical use.

Part 2 covers advanced materials and techniques used in tissue engineering. Topics focus on advanced composite materials for 3D scaffolds and the repair of tissues in different organs such as the heart, cornea, bone and ligaments. Materials highlighted in this part include polyamide composites, electrospun nanofibers, and different bio-based hydrogels.

Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside is a valuable reference for researchers in biomedical engineering, cell biology, and regenerative medicine who want to update their knowledge on current developments in the synthesis and application of functional biomaterials.

Readership:

Medical researchers, orthopedists, rheumatologists, clinicians, rheumatic disease patients

Preface

I would like to congratulate all the authors who took their valuable time to contribute to the book titled “FUNCTIONAL BIO-BASED MATERIALS FOR REGENERATIVE MEDICINE from Bench to Bedside”. This book is a dedication to the founder of the Centre for Tissue Engineering and Regenerative Medicine (CTERM), University Kebangsaan Malaysia, Prof. Dato’ Dr Ruszymah Hj. Idrus. It has been an honour to have been under her supervision and now expanding on our own across the continents through collaborating with talented, hardworking scientists in the tissue engineering and regenerative medicine field on various state-of-the-art technologies and biobased materials used for the tissue-engineered skin, bone, heart, respiratory tract and other vital organs.

In this marvellously insightful book, the authors offer some valuable strategies, technologies and artificial intelligence in the established technology covering tissue engineering as an essential field for various health applications to help not only scientists, researchers and healthcare providers but also the general public to remain updated with the current work happening worldwide.

Mohd Fauzi Mh Busra
Centre for Tissue Engineering and Regenerative Medicine (CTERM)
Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif
Bandar Tun Razak, 56000 Cheras
Kuala Lumpur,
Malaysia

Daniel Law Jia Xian
Centre for Tissue Engineering and Regenerative Medicine (CTERM)
Faculty of Medicine, Universiti Kebangsaan Malaysia, 56000 Cheras
Kuala Lumpur,
Malaysia

Yogeswaran Lokanathan
Centre for Tissue Engineering and Regenerative Medicine (CTERM)
Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif
Bandar Tun Razak, 56000 Cheras
Kuala Lumpur,
Malaysia

&

Ruszymah Haji Idrus
Centre for Tissue Engineering and Regenerative Medicine (CTERM)
Faculty of Medicine Universiti Kebangsaan Malaysia Jalan
Yaacob Latif, Bandar Tun Razak, 56000 Cheras
Kuala Lumpur,
Malaysia

PREFACE II

The regenerative medicine is currently an established technology, covering tissue engineering as a significant field in various health applications. Traditionally, tissue engineering is a combination of cells, biomaterials, and biomolecules to replace or repair damaged tissues. The current advanced technology in the tissue engineering field focuses on the functionalisation of invented bio-based materials. It includes the development of a hybrid or composite biomatrix together with cells-secreted products and related active compounds for better performance in enhancing the rapid therapeutic mechanism. The mode of action for the invented product depends on its formulation or a three-dimensional design of the biomatrix.

This book provides detailed information on the latest advancements in bio-based materials treatment strategy for various tissue applications, encompassing skin, bone, heart, respiratory tract and other vital organs. This is followed by future perspectives on the new emerging treatment in the field of tissue engineering and regenerative medicine.

Mohd Fauzi Mh Busra
Centre for Tissue Engineering and Regenerative Medicine (CTERM)
Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif
Bandar Tun Razak, 56000 Cheras
Kuala Lumpur,
Malaysia

Daniel Law Jia Xian
Centre for Tissue Engineering and Regenerative Medicine (CTERM)
Faculty of Medicine, Universiti Kebangsaan Malaysia, 56000 Cheras
Kuala Lumpur,
Malaysia

Yogeswaran Lokanathan
Centre for Tissue Engineering and Regenerative Medicine (CTERM)
Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif
Bandar Tun Razak, 56000 Cheras
Kuala Lumpur,
Malaysia

&

Ruszymah Haji Idrus
Centre for Tissue Engineering and Regenerative Medicine (CTERM)
Faculty of Medicine Universiti Kebangsaan Malaysia Jalan
Yaacob Latif, Bandar Tun Razak, 56000 Cheras
Kuala Lumpur,
Malaysia